Genomics|Update|Infectious Diseases ▲ Advanced Molecular Detection in Action

Genomics|Update|Infectious Diseases

Volume 34  Number 12  March 26 - April 2, 2015

Advanced Molecular Detection in Action

• Antimicrobials, Vaccines, Interventions
• Detection & Diagnosis
• Epidemiology, Outbreaks, Transmission
• Evolution, Ecology, Pathogenicity, Populations

• Host-Pathogen Interactions
• Methods
• Policy
• Reviews, News & Commentaries

Antimicrobials, Vaccines, Interventions

Detection of vancomycin-resistant Enterococcus faecalis ST6-vanB2 and E. faecium ST915-vanA in faecal samples of wild Rattus rattus in Spain.
Lozano C et al. Vet. Microbiol. 2015 Mar 4.

A continuous peptide epitope reacting with pandemic influenza AH1N1 predicted by bioinformatic approaches.
Carrillo-Vazquez JP et al. J. Mol. Recognit. 2015 Mar 18.

Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells.
Liao HK et al. Nat Commun 2015 6413

Detection of drug-resistant tuberculosis by Xpert MTB/RIF in Swaziland.
Sanchez-Padilla E et al. N. Engl. J. Med. 2015 Mar 19. (12) 1181-2

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Detection and Diagnosis

A novel host-proteome signature for distinguishing between acute bacterial and viral infections.
Oved K et al. PLoS ONE 2015 (3) e0120012

Evaluation of a U.S. public health laboratory service for the molecular detection of drug resistant tuberculosis.
Yakrus MA et al. Tuberc Res Treat 2015 701786 (CDC Author)

Borrelia burgdorferi not confirmed in human-biting Amblyomma americanum ticks from the southeastern United States.
Stromdahl EY et al. J. Clin. Microbiol. 2015 Mar 18. (CDC Author)

Epidemic 2014 enterovirus d68 cross-reacts with human rhinovirus on a respiratory molecular diagnostic platform.
McAllister SC et al. PLoS ONE 2015 (3) e0118529

Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis
Detjen AK, et al. Lancet Respir Med, Mar 23, 2015.

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Epidemiology, Outbreaks, Transmission

Transmission and microevolution of USA300 MRSA in U.S. households: Evidence from whole-genome sequencing.
Alam Md T et al. MBio 2015 (2)

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Evolution, Ecology, Pathogenicity, Populations

Signatures of adaptation in human invasive Salmonella typhimurium ST313 populations from sub-Saharan Africa.
Okoro CK et al. PLoS Negl Trop Dis 2015 Mar (3) e0003611

Genome diversity of Epstein-Barr virus from multiple tumour types and normal infection.
Palser AL et al. J. Virol. 2015 Mar 18.

Complete genome sequence of Corynebacterium minutissimum, an opportunistic pathogen and the causative agent of erythrasma.
Penton PK et al. Genome Announc 2015 (2) (CDC Author)

Molecular characterization of methicillin-resistant Staphylococcus aureus: Characterization of major clones and emergence of epidemic clones of sequence type (ST) 36 and ST 121 in Tehran, Iran.
Moghadam SO et al. FEMS Microbiol. Lett. 2015 Mar 20.

Bacillus cereus from the environment is genetically related to the highly pathogenic B. cereus in Zambia.
Ogawa H et al. J. Vet. Med. Sci. 2015 Mar 23.

Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea viruses associated with outbreaks of severe diarrhea in piglets in Jiangxi, China 2013.
Song D et al. PLoS ONE 2015 (3) e0120310

Banana infecting fungus, Fusarium musae, is also an opportunistic human pathogen: are bananas potential carriers and source of fusariosis?
Triest D et al. Mycologia 2015 Jan-Feb (1) 46-53

Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis
Singh P, et al. Proc Nat Acad Sci, Feb 20, 2015.

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Host-Pathogen Interactions

Hyperdiverse gene cluster in snail host conveys resistance to human schistosome parasites.
Tennessen JA et al. PLoS Genet. 2015 Mar (3) e1005067

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Methods

Accurate read-based metagenome characterization using a hierarchical suite of unique signatures.
Freitas TAK et al. Nucleic Acids Res. 2015 Mar 12.

Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne viruses.
O'Brien CA et al. PLoS Negl Trop Dis 2015 Mar (3) e0003629

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Policy

JAMA Forum: Using health care data to track and improve public health 
Sharfstein JM. news@JAMA, Mar 25, 2015.

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Reviews, News and Commentaries

Extreme cryptography paves way to personalized medicine
Hayden EC. Nature, Mar 23, 2015.

Have research ethics committees got it wrong? A new study looks at what participants in medical research actually want
Kelly SE, Prainsack B. Huff Post Science, Mar 25, 2015.

Open labware: 3-D printing your own lab equipment.
Baden T et al. PLoS Biol. 2015 Mar (3) e1002086

Emergency treatment for exposure to Ebola virus: The need to fast-track promising vaccines.
Geisbert TW et al. JAMA 2015 Mar 24. (12) 1221-1222

Antimicrobial stewardship: the role of scientists?
Bowater L et al. J. Antimicrob. Chemother. 2015 Mar 19.

MERS surges again, but pandemic jitters ease
Kupferschmidt K. Science 20 March 2015; 347: 1296-1297

Study IDs TB strains in Swaziland with drug resistance mutations not detected by Cepheid Xpert test
Johnson M. GenomeWeb, Mar 19, 2015.

CDC scores poorly on biosafety 
Akst J. The Scientist, Mar 25, 2015.

Cepheid Ebola assay granted FDA emergency use authorization
GenomeWeb, Mar 24, 2015.

Population genetics technologies to open US space, aims for 2016 launch of FDA-cleared HIV Dx
Heger M. GenomeWeb, Mar 23, 2015.

Scripps study shows clinical utility of nanosphere gram-positive blood culture test
GenomeWeb, Mar 25, 2015.

MDx firm immunetics developing PCR and array-based fungal Dx
Ashford M. GenomeWeb, Mar 24, 2015.