An informatics research agenda to support precision medicine: seven key areas. - PubMed - NCBI
An informatics research agenda to support precision medicine: seven key areas.
Tenenbaum JD1,
Avillach P2,
Benham-Hutchins M3,
Breitenstein MK4,
Crowgey EL5,
Hoffman MA6,
Jiang X7,
Madhavan S8,
Mattison JE9,
Nagarajan R10,
Ray B11,
Shin D12,
Visweswaran S13,
Zhao Z14,
Freimuth RR4.
Abstract
The recent announcement of the Precision Medicine Initiative by President Obama has brought precision medicine (PM) to the forefront for healthcare providers, researchers, regulators, innovators, and funders alike. As technologies continue to evolve and datasets grow in magnitude, a strong computational infrastructure will be essential to realize PM's vision of improved healthcare derived from personal data. In addition, informatics research and innovation affords a tremendous opportunity to drive the science underlying PM. The informatics community must lead the development of technologies and methodologies that will increase the discovery and application of biomedical knowledge through close collaboration between researchers, clinicians, and patients. This perspective highlights seven key areas that are in need of further informatics research and innovation to support the realization of PM. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
KEYWORDS:
biomarkers; data sharing; informatics; precision medicine
- PMID:
- 27107452
- [PubMed - as supplied by publisher]
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