- In 2016, 48.5 million Americans used illicit drugs or misused prescription drugs [PDF-6.2MB].
- Around 66% of the more than 63,000 drug overdose deaths in 2016 involved a prescription or illicit opioid.
- States can use data on nonfatal overdoses and overdose deaths to inform their prevention activities, and healthcare providers can take CDC’s online training on safer prescribing practices.
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