domingo, 31 de diciembre de 2023
sábado, 30 de diciembre de 2023
Thanks to readers from all over the world
Thank you to everyone who reads me, silently...
thanks to everyone who follows me every day...
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Otros
A Nationwide Network of Health AI Assurance Laboratories. Nigam H Shah et al. JAMA 2023 12
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics
From the abstract: "Given the importance of rigorous development and evaluation standards needed of artificial intelligence (AI) models used in health care, nationwide accepted procedures to provide assurance that the use of AI is fair, appropriate, valid, effective, and safe are urgently needed. While there are several efforts to develop standards and best practices to evaluate AI, there is a gap between having such guidance and the application of such guidance to both existing and new AI models being developed. As of now, there is no publicly available, nationwide mechanism that enables objective evaluation and ongoing assessment of the consequences of using health AI models in clinical care settings. "
Next Generation Public Health Genomics: A Call to Assess the Equitable Implementation, Population Health Impact, and Sustainability of Precision Public Health Applications MC Roberts et al, Public Health Genomics, December 22, 2023
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics
From the article: "The field of Public Health Genomics recently celebrated its twenty-fifth anniversary. Defined by the CDC as responsible and effective translation of genome-based knowledge and technologies for the benefit of population health, public health genomics applications have expanded beyond newborn screening to other applications poised to improve public health. Yet despite the promise and potential for public health genomics, the population health impact and sustainability of public health genomics applications has yet to be fully measured and achieved. Further access to public health genomics applications has been lower among underrepresented racial and ethnic communities, rural communities, and groups with lower education and income, deepening concerns that the field could exacerbate rather than redress health inequities. "
A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial. Rainer Tan et al. Nat Med 2023 12
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics
From the abstract: "Excessive antibiotic use and antimicrobial resistance are major global public health threats. We developed ePOCT+, a digital clinical decision support algorithm in combination with C-reactive protein test, hemoglobin test, pulse oximeter and mentorship, to guide health-care providers in managing acutely sick children under 15?years old. To evaluate the impact of ePOCT+ compared to usual care, we conducted a cluster randomized controlled trial in primary care facilities. The use of ePOCT+ in intervention facilities resulted in a reduction in the coprimary outcome of antibiotic prescription compared to usual care (23.2% versus 70.1%, adjusted difference -46.4%, 95% confidence interval (CI) -57.6 to -35.2). "
2023 Top Ten Roundup: A USU Year-in-Review
As we celebrate the achievements of 2023, we are proud to present our top ten articles that have not only garnered the most views but have also sparked meaningful conversations across the military medical community.
https://news.usuhs.edu/2023/12/2023-top-ten-roundup-usu-year-in-review.html?utm_medium=govdelivery&utm_source=email
viernes, 29 de diciembre de 2023
HOSPITAL TO HOME: NURSES HELP NAVIGATE THEIR PATIENTS’ RECOVERY
Hospital to Home: Nurses Help Navigate Their Patients’ Recovery
By Ivanhoe Broadcast News on January 1, 2024
https://www.ivanhoe.com/?p=32088&preview=1&_ppp=84a1f596bc
jueves, 28 de diciembre de 2023
miércoles, 27 de diciembre de 2023
“Global Brain” enters third decade
https://www.fic.nih.gov/?utm_source=funding-news&utm_medium=email&utm_campaign=funding-news
Neurological disorders are the leading cause of disability and the second leading cause of death worldwide. Fogarty's Global Brain program, now in its 20th year, funds projects that aim to improve brain health outcomes in low- and middle-income countries.
martes, 26 de diciembre de 2023
lunes, 25 de diciembre de 2023
domingo, 24 de diciembre de 2023
Attitudes toward pre-symptomatic screening for Alzheimer’s dementia in five European countries: a comparison of family members of people with Alzheimer’s dementia versus non-family members IA Angelidou et al, Frontiers Genetics, December 2023
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/15/2023
From the abstract: " Pre-symptomatic screening is getting more attention in healthcare as it detects the risk for developing neurodegenerative diseases like Alzheimer’s disease (AD), which is very useful for treatment or prevention. AD screening could play an important role in individuals with at least one affected first-degree relative, but also without family history. As the demand for screening is rising worldwide, it is important to consider possible cross-cultural differences in attitudes toward pre-symptomatic screening."
How Holiday Conversations About Cancer Can Save Lives G Burst, Cure, December 13, 2023
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/17/2023
From the article: "Silently plaguing our family is Lynch syndrome, a hereditary cancer syndrome that increases the risk of developing various cancers. This genetic predisposition often goes undetected, affecting approximately 1 in 279 Americans. Lynch syndrome arises from mutations in genes responsible for DNA error repair, potentially leading to tumor formation and triggering cancer. Knowing your family history of Lynch syndrome can be a life-saving intervention. Sadly, it took two of my brothers to develop cancer before I became aware of it. Early detection and screening have reduced my risk of developing cancer and since my diagnosis of having Lynch syndrome, treatment options for those who develop Lynch syndrome cancers have advanced considerably. "
Newborn Screening for Severe Combined Immunodeficiency: Lessons Learned from Screening and Follow-Up of the Preterm Newborn Population A Gaviglio et al, IJNS, December 2023
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/18/2023
From the abstract: " Newborn screening (NBS) for Severe Combined Immunodeficiency (SCID) by measurement of T-cell receptor excision circles (TRECs) successfully identifies newborns with SCID and severe T-cell lymphopenia, as intended. At the same time, NBS programs face the challenge of false positive results, with a disproportionately high number in the premature newborn population. This study evaluates TREC values and SCID screening outcomes in premature newborns and elucidates evidence-based SCID screening practices that reduce unnecessary follow-up activities in this population."
Organizational Factors in Clinical Data Sharing for Artificial Intelligence in Health Care. Alaa Youssef et al. JAMA Netw Open 2023 12 (12) e2348422
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=archive&date=12/20/2023
From the abstract: "Are organizational factors associated with the motivation of health organizations to share clinical data for artificial intelligence (AI) development? In this qualitative study, 27 leaders from 18 health organizations were interviewed, and a predominant concern among them was data privacy risks. Most stakeholders viewed these as a substantial barrier for public health data sharing due to potential liability and reputational consequences; however, they identified external incentives as key factors for enhancing organizational motivation and fostering both within and across-sector data-sharing collaborations for AI development. The findings of this study suggest that data-sharing policies should be rooted in feasibility and incentivization strategies to promote responsible and equitable AI development in the health care sector. "
Next Generation Public Health Genomics: A Call to Assess the Equitable Implementation, Population Health Impact, and Sustainability of Precision Public Health Applications MC Roberts et al, Public Health Genomics, December 22, 2023
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=all%20hot%20topics
From the article: "The field of Public Health Genomics recently celebrated its twenty-fifth anniversary. Defined by the CDC as responsible and effective translation of genome-based knowledge and technologies for the benefit of population health, public health genomics applications have expanded beyond newborn screening to other applications poised to improve public health. Yet despite the promise and potential for public health genomics, the population health impact and sustainability of public health genomics applications has yet to be fully measured and achieved. Further access to public health genomics applications has been lower among underrepresented racial and ethnic communities, rural communities, and groups with lower education and income, deepening concerns that the field could exacerbate rather than redress health inequities. "
sábado, 23 de diciembre de 2023
2023 in Nine Charts: A Growing Inequality
https://www.worldbank.org/en/news/feature/2023/12/18/2023-in-nine-charts-a-growing-inequality
If 2022 was a year of uncertainty, 2023 is the year of inequality. For countries hoping to bounce back from the devastating losses of the COVID-19 pandemic, the battle has been made tougher by the compounding threats of climate change, fragility, conflict and violence, or food insecurity, to name a few—that make it difficult for economies across the board to fully recover.
2023 en neuf graphiques : les inégalités se creusent dans le monde
https://www.banquemondiale.org/fr/news/feature/2023/12/18/2023-in-nine-charts-a-growing-inequality
Alors que 2022 avait été une année de fortes incertitudes, 2023 sera placée sous le signe des inégalités. Après la pandémie de COVID-19 et des pertes dévastatrices, les économies peinent globalement à reprendre de la vigueur, plombées par les effets conjugués de multiples crises : changement climatique, conflits, insécurité alimentaire, pour n’en citer que quelques-unes.
2023 en nueve gráficos: El aumento de la desigualdad
https://www.bancomundial.org/es/news/feature/2023/12/18/2023-in-nine-charts-a-growing-inequality?cid=ECR_E_NewsletterWeekly_ES_EXT&deliveryName=DM204980#
Si 2022 fue un año de incertidumbres, 2023 es el año de la desigualdad. Para los países que esperan recuperarse de las devastadoras pérdidas provocadas por la pandemia de COVID-19, la batalla se ha vuelto más difícil debido a las amenazas combinadas del cambio climático; la fragilidad, los conflictos y la violencia, o la inseguridad alimentaria, por nombrar solo algunas, que dificultan la plena recuperación de todas las economías.
viernes, 22 de diciembre de 2023
National Survey on Clinical Trials
https://www.researchamerica.org/wp-content/uploads/2023/12/2023-National-Survey-on-Clinical-Trials.pdf?utm_campaign=morning_rounds&utm_medium=email&_hsmi=287377255&_hsenc=p2ANqtz-_atWabIrAUMLaQ9mU_2Z53IOwPyqLZls1fT4LLVTZLowqB1D9iWHnIcDkkZOeXw5JDtRI8Ab8ImDmdsEBsyNqdSVU8yw&utm_content=287377255&utm_source=hs_email
Drugs are still mostly tested in white men. Will the FDA change that next year?
John Wilkerson
By John Wilkerson Dec. 21, 2023
https://www.statnews.com/2023/12/21/clinical-trial-diversity-fda/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=287377255&_hsenc=p2ANqtz-_4M-0BFf3xJEdUIhs-0z8qG0jn8tMfp1dJh5ugakjrauBafT5BFdNWqOhCfQz2G94f2KdNnj-kCvUlLBgYQk7-7WFHBA&utm_content=287377255&utm_source=hs_email
Drug-Device Combination Products: Updates and Challenges with Demonstrating Generic Substitutability Date and Time: March 14, 2024 , 8:30 am – 6:00 pm , March 15, 2024 , 8:30 am – 4:40 pm
https://www.complexgenerics.org/education-training/drug-device-combination-products-updates-and-challenges-with-demonstrating-generic-substitutability/?utm_medium=email&utm_source=govdelivery
This 2-day hybrid (virtual and in-person) workshop is focused on addressing current challenges associated with developing complex generic drug-device combination products (DDCPs). This workshop is primarily for the generic drug industry and other collaborators involved with generic DDCP development and assessment, including human factors consultants and contract research organizations.
This workshop will be held virtually and in-person at The Universities at Shady Grove, Rockville, MD.
Virtual Attendance is optimal for an audience interested in conveniently receiving helpful advice and practical information on the current thinking and best practices related to developing complex generic DDCPs. Virtual attendees will enjoy free access to all symposia, except Symposium III, including opportunities to:
Attend all presentations and panel discussions, including a dedicated “Ask the FDA” session
Submit live questions online for discussion panel Q&As
Enjoy free access to workshop recordings of presentations and panel discussions (not including the in-person working sessions in Symposium III: Setting the Course for the DDCP Future)
In-Person Attendance is optimal for an audience interested in actively engaging with FDA and industry colleagues to discuss complex issues, resolve current problems, provide insights, detail industry experience about implementation challenges and discuss alternative approaches to comparative user interface assessment. In-person attendees will also play an active role in conversations related to the future direction of this field during Symposium III by:
Participating in working sessions on four challenging aspects of comparative user interface assessment
Collaborating with FDA and industry thought leaders to define knowledge gaps, resource needs, and next steps
Informing a “roadmap” for a CRCG working committee that will collaborate with FDA to plan and prioritize next steps and formulate research questions to address and bridge the gaps in comparative user interface assessment
Conversing with panelists during discussion panel Q&As, including a dedicated “Ask the FDA” session
Networking with colleagues during breaks with light snacks and beverages, and catered lunches
For more information, please visit https://www.complexgenerics.org/education-training/drug-device-combination-products-updates-and-challenges-with-demonstrating-generic-substitutability/.
jueves, 21 de diciembre de 2023
Global launch of The Lancet Child & Adolescent Health Series on racism and child health in the USA Jan 26, 2024 15:00 GMT / 10:00 EST
https://www.thelancet.com/webinars?dgcid=hubspot_email_conferencealerts_amslancetinternationalhealthlecture23&utm_campaign=lancet-conf-alerts22&utm_medium=email&_hsmi=287276795&_hsenc=p2ANqtz--RuSvt179lpmJ6slr9OqqeCF6PNR-Hr16njf_g_4E839I9ZRodpJKv85ZUJzDCBc-G-VnPsx98cgilIUsRJspduqNPHg&utm_content=287276795&utm_source=hs_email
Societal structures and systems—including healthcare, education, and housing—act individually and in combination to create and perpetuate structural racism in the USA, which influences a child’s opportunity for healthy development. Join the authors and an expert panel for the global launch of The Lancet Child & Adolescent Health’s new Series on racism and child health in the USA. The panel will explore how racial and ethnic inequities affect the quality of paediatric care in the USA, before proposing policy solutions to help eliminate child health disparities.
https://www.thelancet.com/webinars?dgcid=hubspot_email_conferencealerts_amslancetinternationalhealthlecture23&utm_campaign=lancet-conf-alerts22&utm_medium=email&_hsmi=287276795&_hsenc=p2ANqtz--RuSvt179lpmJ6slr9OqqeCF6PNR-Hr16njf_g_4E839I9ZRodpJKv85ZUJzDCBc-G-VnPsx98cgilIUsRJspduqNPHg&utm_content=287276795&utm_source=hs_email
Webinar - Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions Final Guidance - January 11, 2024
https://www.fda.gov/medical-devices/workshops-conferences-medical-devices/cdrh-webinars?utm_medium=email&utm_source=govdelivery
Webinar - Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions Final Guidance
JANUARY 11, 2024
https://www.fda.gov/medical-devices/workshops-conferences-medical-devices/webinar-assessing-credibility-computational-modeling-and-simulation-medical-device-submissions-final
Improving Response Rates and Representativeness for CAHPS Survey Data: An Overview of Web-First and Other Strategies (Webcast)
Improving Response Rates and Representativeness for CAHPS Survey Data: An Overview of Web-First and Other Strategies (Webcast): This AHRQ webcast will provide strategies for improving survey response rates and the representativeness of survey data, particularly for those surveys required by the Centers for Medicare & Medicaid Services (CMS).
AHRQ Emergency Department Prevention Quality Indicators (ED PQI) Beta v2023 Software – New Resources!
https://qualityindicators.ahrq.gov/software/win_qi#ed-pqi-software
AHRQ video tutorials to help users calculate ED PQI measures are now available on the AHRQ QI website. The tutorials demonstrate:
ED PQI module resources such as technical measure specifications, national benchmarks, risk adjustment parameter estimates and software release notes,
Downloading and installing the Windows software, and
Using the ED PQI Windows software.
The ED PQI are area-level measures providing insight into health system performance and population health by measuring the frequency of ED visits for conditions that could be managed outside the hospital by high-quality, community-based care. The ED PQI measures intend to identify targets for public health services improvement, help identify disparities or gaps in care, and indicate the potential impact of interventions aimed at improved health system functioning.
Beta testing by a limited number of users will involve applying the ED PQI beta software to their own ICD-10-CM/PCS hospital data and report any issues encountered during testing. Feedback will help AHRQ make future improvements. AHRQ is extending the deadline to December 29, 2023 for beta testers to express interest.
Interested organizations should express interest with an email to QISupport@ahrq.hhs.gov with the subject line: AHRQ QI v2023 ED PQI Beta Testing Opportunities. Beta testing will run from January 5 to February 16, 2024.
2023 National Healthcare Quality and Disparities Report
2023 National Healthcare Quality and Disparities Report: For the 21st year, AHRQ is reporting on healthcare quality and disparities. The annual National Healthcare Quality and Disparities Report is mandated by Congress to provide a comprehensive overview of the quality of healthcare received by the general U.S. population and disparities in care experienced by different racial and socioeconomic groups. The report is produced with the help of an Interagency Work Group led by AHRQ.
miércoles, 20 de diciembre de 2023
Genitourinary Syndrome of Menopause: A Systematic Review
Genitourinary Syndrome of Menopause: A Systematic Review: Genitourinary Syndrome of Menopause: A Systematic Review
2023 National Healthcare Quality and Disparities Report
2023 National Healthcare Quality and Disparities Report: For the 21st year, AHRQ is reporting on healthcare quality and disparities. The annual National Healthcare Quality and Disparities Report is mandated by Congress to provide a comprehensive overview of the quality of healthcare received by the general U.S. population and disparities in care experienced by different racial and socioeconomic groups. The report is produced with the help of an Interagency Work Group led by AHRQ.
AHRQ Supports Efforts To Examine and Address Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Health and Healthcare
AHRQ Supports Efforts To Examine and Address Impact of Healthcare Algorithms on Racial and Ethnic Disparities in Health and Healthcare: Algorithms are mathematical formulas and models that combine different input variables or factors to inform a calculation or an estimate—frequently an estimate of risk. In healthcare, algorithms are frequently used to guide clinical decision making both at the point of care and as part of resource allocation and healthcare management. They are increasingly incorporated into healthcare decision tools, such as clinical guidelines, pathways, clinical decision support programs in electronic health records, and operational systems used by health systems and payers.
Guiding Principles Help Healthcare Community Address Potential Bias Resulting from Algorithms
Guiding Principles Help Healthcare Community Address Potential Bias Resulting from Algorithms: A new paper addresses the use of algorithms in healthcare, their impact on racial/ethnic disparities in care, and approaches to identify and mitigate biases.
martes, 19 de diciembre de 2023
AHRQ will be conducting a Winter MEPS-HC Hands-on Webinar series on January 30, 31 and February 1, 2024.
https://meps.ahrq.gov/mepsweb/about_meps/workshops_events.jsp
This advanced programming webinar series will cover an applied example of how to link the MEPS-HC Medical Conditions public use data file to the Prescribed Medicines public use data file in three separate languages: STATA, SAS, and R. Each webinar will consist of a short lecture designed to provide a general overview of the files, followed by hands-on session working with the instructor. The webinar series will help with the challenges researchers face while linking the MEPS-HC Medical Conditions public use data file to the Prescribed Medicines public use data file. Familiarity with the programming language of your choice is strongly recommended.
Registration link will be available in the late December on: http://meps.ahrq.gov/mepsweb/about_meps/workshops_events.jsp.
Guiding Principles Help Healthcare Community Address Potential Bias Resulting from Algorithms
Guiding Principles Help Healthcare Community Address Potential Bias Resulting from Algorithms: A new paper addresses the use of algorithms in healthcare, their impact on racial/ethnic disparities in care, and approaches to identify and mitigate biases.
lunes, 18 de diciembre de 2023
An Overview of the SOPS Surveys for New Users (Webcast)
An Overview of the SOPS Surveys for New Users (Webcast): This webcast provided an overview of the AHRQ Surveys on Patient Safety Culture™ (SOPS®). The speakers described the SOPS program, the SOPS surveys, supplemental item sets, databases, and resources available to SOPS users.