viernes, 26 de julio de 2024
Infant Mortality in the United States, 2022: Data From the Period Linked Birth/Infant Death File
https://www.cdc.gov/nchs/data/nvsr/nvsr73/nvsr73-05.pdf?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--l_AzmZD-PdbG5HolTVuhKrShCVwM3r4hVWrbbx6v6PefbkertpgR08rBMdINJ78SHW-Q5pu-iKDJlr2q-3o6Oog9BJQ&_hsmi=317225391&utm_content=317225391&utm_source=hs_email
U.S. infant mortality rose 3% in 2022, per CDC
Infant deaths were up 3% in 2022 from 2021, according to new CDC data published today in its National Vital Statistics Report. The rate was 5.61 deaths per 1,000 live births overall, but varied widely by race. Black women lost babies at the highest rate, at 10.9 per 1,000. White women lost babies at a rate of 4.52 per 1,000.
Infant mortality rates measure the number of babies that die before they reach their first birthday. The 3% increase is the first statistically significant increase in two decades, the authors of a provisional report on the numbers said late last year. The number has generally been decreasing over the years, so despite the increase, 2022’s rate is still below where it was back in 2002.
The leading causes of death for infants were the same in 2022 as 2021: congenital malformations and disorders related to short gestation and low birth weight. But there was one cause of death that became more common. Infant deaths due to maternal complications from pregnancy jumped from 30.4 to 33.1 deaths per 1,000 live births.
FDA alerts health care providers, compounders and patients of dosing errors associated with compounded injectable semaglutide products
https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-patients-dosing-errors-associated-compounded?utm_medium=email&utm_source=govdelivery
FDA alerts health care providers, compounders and patients of dosing errors associated with compounded injectable semaglutide products
FDA has received reports of adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products. Dosing errors have resulted from patients measuring and self-administering incorrect doses of the drug and health care providers miscalculating doses of the drug.
FDA encourages health care providers and compounders to provide patients with the appropriate syringe size for the intended dose and counsel patients on how to measure the intended dose using the syringe.
The agency also encourages patients to talk with their health care provider or compounder about how to measure and administer the intended dose of compounded semaglutide.
FDA Approves HPV Tests That Allow for Self-Collection in a Health Care Setting
https://www.cancer.gov/news-events/cancer-currents-blog/2024/fda-hpv-test-self-collection-health-care-setting?cid=eb_govdel
On May 14, the Food and Drug Administration (FDA) expanded the approvals of two tests that detect cancer-causing types of human papillomavirus (HPV) in the cervix. Both tests are used as part of screening for cervical cancer.
Call for Papers: Supplemental Issue of Prevention Science Structural Approaches to Youth Violence Prevention: Addressing Racism and Discrimination Released: May 31, 2024 Letters of intent due: September 30, 2024
https://nimhd.nih.gov/about/publications/call-for-papers-supplemental-issue-of-prevention-science.html?utm_medium=email&utm_source=govdelivery
Submit Your Letter of Intent by September 30, 2024
NIMHD is inviting researchers to contribute to an upcoming supplemental issue of the journal Prevention Science. This supplemental issue will focus on youth violence prevention interventions that address structural racism and discrimination, and other structural factors and social determinants.
Topics of Interest:
Empirical research on the impact of interventions on individual, community, social, and structural factors.
Prospective intervention studies and natural policy experiments at local, state, regional, or national levels.
Conceptual papers that describe current challenges and viable solutions to implementing sustainable multilevel, multisectoral interventions that address social and structural factors that place youth at highest risk for violence as well as those that address disparities in youth violence.
Authors interested in contributing should submit a letter of intent by September 30, 2024.
Real-World Data: Assessing Electronic Health Records and Medical Claims Data To Support Regulatory Decision-Making for Drug and Biological Products Guidance for Industry July 2024
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/real-world-data-assessing-electronic-health-records-and-medical-claims-data-support-regulatory?utm_medium=email&utm_source=govdelivery
FDA issued the final guidance Real-World Data: Assessing Electronic Health Records and Medical Claims Data to Support Regulatory Decision-Making for Drug and Biological Products.
The guidance includes recommendations for sponsors and other interested parties proposing to use data from electronic health records (EHRs) or medical claims to help support a new use of an FDA-approved drug or biological product or to help support or satisfy post-approval study requirements.
FDA issued the draft version of the guidance in September 2021 and considered public comments when finalizing the guidance. Changes from the draft to the final guidance include:
clarifying the considerations for selecting study variables for validation, and the extent of effort needed for validation;
noting that choice of a reference standard for validation may vary according to study-specific factors;
recommending the use of quantitative approaches to demonstrate whether and how study findings might be impacted if certain key study variable(s) are misclassified; and
removing from the glossary defined terms that are generally understood and transferring other relevant definitions from the glossary to the text in the guidance.
The US will pay Moderna $176 million to develop an mRNA pandemic flu vaccine
https://apnews.com/article/bird-flu-moderna-vaccine-mrna-pandemic-7f15d8d274a24d89fa86e2f57e13cbff?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-8mc8JHBVrDPYVczvTd5gt_78yBdcRIyAaoV9WwpuhPKptDODS2SjkYKCzLgW-GAPPKjSO1aZAelDF_ARa8-amU2kZcqw&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
Bird Flu: H5N1 bird flu has continued infecting animals throughout the U.S., and, as of July 21, 10 human cases have been reported in the U.S. In July, news outlets reported that Moderna is developing an mRNA bird flu vaccine that can be distributed if further human outbreaks occur. Most of the 42,000 posts, articles, comments and videos mentioning bird flu and Moderna in the past 30 days were published immediately following the announcement. Some of the most popular social media posts falsely claim that bird flu is a “hoax” designed to make money for pharmaceutical companies or that bird flu vaccines are part of a “depopulation plan.”
https://www.cdc.gov/bird-flu/spotlights/h5n1-response-07192024.html?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz--l6WfdVFESnNwlD2yn6A0AgSmeNmtViLPC4hRW-wT37KyfzfBfTuTFTOVLZXWPWRSwL3RH17r0tls_Q3FZsB4Vp4F3cw&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
Kansas Cites Misleading Claims About Vaccine Safety in Lawsuit Against Pfizer
https://www.reuters.com/business/healthcare-pharmaceuticals/us-fda-adds-warning-about-rare-heart-inflammation-pfizer-moderna-covid-vaccines-2021-06-26/?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-9WIR3bENt_oVvVDx_jrd1V8ZZvJnHfFSnPR1YHiEfVGJKG6iAU0OLMK3sqgYGq15fF1HbIdhYu1Dw9h9OylvrefuiYrg&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
Kansas Cites Misleading Claims About Vaccine Safety in Lawsuit Against Pfizer
Kansas Attorney General Kris Kobach filed a lawsuit against Pfizer last month, resurfacing false claims about vaccine safety. Kobach accuses Pfizer of downplaying potential risks such as myocarditis and pregnancy complications, citing misinformation to support the lawsuit. However, the chance of developing myocarditis after vaccination is rare and the FDA already issued a myocarditis warning last year. Studies also show that the COVID-19 vaccine does not increase the risk of miscarriage.
https://www.nature.com/articles/s41598-024-57880-8?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz-_EOmNSLrzqj8lV2SAK8ylavkqiTbRV4Fh93CJIJTws4EZ3Y6dnpR-St9J4gwE6wh7UTsAUM8UQ6YQEZIHpWB_rtPMV-w&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
Following the announcement of the lawsuit, there was a spike in social media posts about Pfizer. The top five posts came from accounts known for opposing vaccines, and they all expressed distrust of Pfizer. Some of these posts and comments echoed the lawsuit’s false claim that COVID-19 vaccines carry a high risk of heart inflammation. For example, one post said “...it's definitely not normal for children to have heart attacks. I'm so happy I stayed strong and refused to put this in my family.” Many posts also suggested that pharmaceutical companies should be held accountable for alleged wrongdoing. Another post said, “Every state has to hold these companies accountable for injecting poison into people’s bodies.”
https://www.factcheck.org/2023/04/scicheck-no-evidence-excess-deaths-linked-to-vaccines-contrary-to-claims-online/?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz--4ANG1AvxvhEYXEMeZ-1PBnDSqB7MuHm-I9DPFak31I3SO4BqD76oCXdNliWnKDqqdmOa4vmCHLVaP_K0wn4P7l0ClDw&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
The false narratives suggest that vaccine opponents are leaning on years-old talking points to discourage COVID-19 vaccination, despite extensive research showing that COVID-19 vaccines have not caused mass death and that heart inflammation is much more common and more severe after a COVID-19 infection, not vaccination. We expect vaccine opponents to continue recycling false claims when major COVID-19 related news occurs.
https://publicgoodnews.com/2023/12/25/myocarditis-facts-covid-19-vaccines-fact-check/?utm_campaign=KFF-Misinformation-Trust&utm_medium=email&_hsenc=p2ANqtz--ba3qxmMBxj0d8M9fPoK3nIr5sMnDOQ1dZxYP0pYFhWRVl2nXk0pf5tNwpEKmQ-zz2dWLpQktcR1fNpE1O5fuehgyFzA&_hsmi=317302400&utm_content=317302400&utm_source=hs_email
Drugs for the Treatment of Partial Onset Seizures: Extrapolation of Efficacy from Adults to Pediatric Patients 1 Month of Age and Older July 2024
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/drugs-treatment-partial-onset-seizures-extrapolation-efficacy-adults-pediatric-patients-1-month-age?utm_medium=email&utm_source=govdelivery
FDA Announces Availability of a Revised Final Guidance on Extrapolating Efficacy Data to Treat Partial Onset Seizures in Pediatric Patients
On July 15, 2024, the FDA announced the availability of a revised final guidance for industry entitled Drugs for the Treatment of Partial Onset Seizures: Extrapolation of Efficacy from Adults to Pediatric Patients 1 Month of Age and Older, replacing the 2019 final guidance which discussed extrapolation to pediatric patients 4 years of age and older. This revised final guidance provides recommendations to sponsors on the clinical development of drugs for the treatment of partial onset seizures (POS) in pediatric patients. Specifically, this guidance addresses FDA’s current thinking regarding clinical development programs that can support extrapolation of the efficacy of drugs approved for the treatment of POS in adults to pediatric patients 1 month of age and older. This guidance discusses formulation development, efficacy and safety considerations, and clinical pharmacology and dosing considerations. This guidance does not address the development of drugs to treat other types of seizures.
Historically, efficacy for the treatment of POS in pediatric patients was established by performing one or more adequate and well-controlled clinical studies in pediatric patients. However, efficacy can be extrapolated from adults to pediatric patients when it is reasonable to assume that children, compared with adults, have a similar progression of disease, similar response of disease to treatment, and similar exposure-response relationship. Initial systematic and quantitative analyses conducted by FDA, using data from clinical studies of drugs with a variety of putative mechanisms of action approved for the treatment of POS in both adults and pediatric patients, have shown that the relationship between exposure and response (reduction in seizure frequency) is similar in adults and pediatric patients 4 years of age and older. Subsequent evaluation by FDA determined that POS are readily identifiable in pediatric patients down to 1 month of age and are phenomenologically and pathophysiologically very similar to those in older patients. These analyses and observations have allowed FDA to conclude that the efficacy of drugs approved for the treatment of POS can be extrapolated from adults to pediatric patients 1 month of age and older.
The Role of Health Care in the New Presidential Election Drew Altman Published: Jul 25, 2024
https://www.kff.org/from-drew-altman/the-role-of-health-care-in-the-new-presidential-election/
There is no Clinton health reform plan or (then) controversial Obamacare plan to command the attention of voters in this presidential election. Former President Trump will focus on other issues he views as advantageous—not health care—and Vice President Harris is unlikely to make new health proposals of her own. Nevertheless, health is likely to be a consequential factor in the campaign. Here’s how.
Inflation Reduction Act Health Insurance Subsidies: What is Their Impact and What Would Happen if They Expire? Jared Ortaliza, Anna Cord, Matt McGough, Justin Lo, and Cynthia Cox Published: Jul 26, 2024
Inflation Reduction Act Health Insurance Subsidies: What is Their Impact and What Would Happen if They Expire?
Jared Ortaliza, Anna Cord, Matt McGough, Justin Lo, and Cynthia Cox
Published: Jul 26, 2024
MEDIA CONTACT:
Tammie Smith | 202.654.1410 | TammieS@kff.org
https://www.kff.org/private-insurance/issue-brief/inflation-reduction-act-health-insurance-subsidies-what-is-their-impact-and-what-would-happen-if-they-expire/?utm_campaign=KFF%3A%20Health%20Costs&utm_medium=email&_hsenc=p2ANqtz--xOWtxQmAOd89ZNkJtNHu47V4h7fjTZRitT1eRDwg7YYCK47veVTGkp7rkefqwdoZZTDHYn0T24TECkS5uOfmUSofHWg&_hsmi=317379267&utm_content=317379267&utm_source=hs_email
ACA Marketplace Enrollees Will See Steep Increases in Premium Payments in 2026 if Enhanced Subsidies Expire
Enrollees in 12 HealthCare.gov states would see their monthly payments at least double on average without enhanced subsidies
Without the enhanced subsidies in the Inflation Reduction Act (IRA), Affordable Care Act (ACA) Marketplace enrollees in 12 of the states that use HealthCare.gov would see their monthly premium payments at least double on average, according to a new KFF analysis. Enrollees in three states would see the steepest annual increases: Wyoming (195% or $1,872), Alaska (125% or $1,836), and West Virginia (133% or $1,404), and premiums would rise by an average of 93% or $624 overall in HealthCare.gov states.
The results of the 2024 elections will likely play a major role in whether the enhanced subsidies are extended beyond 2025. Nationally, enhanced subsidies have cut premium payments by an estimated 44% ($705 annually) on average for people receiving a subsidy. If they expire, almost all subsidized ACA Marketplace enrollees, including those in state-run marketplaces, would experience steep increases in premium payments in 2026. Because enhanced subsidies have made Marketplace coverage more affordable for low- and middle-income people, they would be the most impacted by a potential subsidy expiration.
Enrollees with low incomes would see the greatest jump in their premium payments. For example, a 45-year-old enrollee earning $25,000 on average would pay 573% ($917) more annually for a benchmark silver plan (from $160 with enhanced subsidies to $1,077 without them).
The number of people with Marketplace coverage nearly doubled since the enhanced subsidies began in 2021, from 11.4 million in 2020 to 21.4 million in 2024. This enrollment growth has been concentrated among low-income individuals, spurred by the availability of low-cost (and in some cases, zero-premium) plans made available by the enhanced subsidies. Zero-premium plans are available to a larger share of ACA Marketplace enrollees in the 10 states that have not expanded Medicaid. Among states that use HealthCare.gov, enrollees in Florida and Texas received the most ($2.2 and $1.5 billion respectively) in enhanced IRA subsidies in 2024.
jueves, 25 de julio de 2024
A clinical pharmacist-led transitions of care program for veterans with two planned care transitions (hospital to skilled care and skilled care to home) amid the COVID-19 pandemic. July 24, 2024
https://psnet.ahrq.gov/issue/clinical-pharmacist-led-transitions-care-program-veterans-two-planned-care-transitions
Transitions of care between health care settings and home can introduce opportunities for adverse events, particularly among vulnerable patients. This article describes the pilot implementation of the Geriatric High-Risk Evaluation and Liaison Program – Transitional Care (GHELP-TC) which aims to improve care transitions between acute care to skilled nursing and skilled nursing to home for older veterans. This pilot evaluation identified 79 medication errors and 80 appointment errors among 90 enrolled veterans. A planned expanded implementation will include registered nurses (RNs) to improve communication and accountability.
Partnership as a pathway to diagnostic excellence: the challenges and successes of implementing the Safer Dx Learning Lab. July 24, 2024
https://psnet.ahrq.gov/issue/partnership-pathway-diagnostic-excellence-challenges-and-successes-implementing-safer-dx
Partnership as a pathway to diagnostic excellence: the challenges and successes of implementing the Safer Dx Learning Lab.
Sloane J, Singh H, Upadhyay DK, et al. Jt Comm J Qual Patient Saf. 2024;Epub May 31.
Improving the diagnostic process requires multipronged and multidisciplinary approaches to achieve lasting improvements. This qualitative study involving 25 individuals associated with the Safer Dx Learning Lab identified several program successes, such as improved reporting workflow and safety culture fostering psychological safety. Participants also highlighted lessons learned, including leadership buy-in and the need for protected time for clinicians to participate in case review and continuous learning.
A human right-based approach to dealing with adverse events in residential care facilities. July 24, 2024
https://psnet.ahrq.gov/issue/human-right-based-approach-dealing-adverse-events-residential-care-facilities
A human right-based approach to dealing with adverse events in residential care facilities.
McGrane N, Behan L, Keyes LM. Health Hum Rights. 2024;26(1):115-128.
Many regulatory authorities require notification of adverse events involving vulnerable individuals, such as those in care facilities. In this study, almost 200 statutory notifications from residential care facilities (RCF; e.g., nursing homes, assisted living) were analyzed to ensure residents' human rights (fairness, respect, equality, dignity, and autonomy) were upheld during adverse events. In the majority of adverse events and their management, residents' human rights were upheld.
Long-term care healthcare-associated infections in 2023: an analysis of 23,970 reports. July 24, 2024
https://psnet.ahrq.gov/issue/long-term-care-healthcare-associated-infections-2023-analysis-23970-reports
Long-term care healthcare-associated infections in 2023: an analysis of 23,970 reports.
Kepner S, Bennett A, Jones RM. Patient Safety. 2024;6(1).
Preventing healthcare-associated infections continue to be a challenge in long-term care settings. Based on reports submitted by long-term care facilities to the Pennsylvania Patient Safety Reporting System (PA-PSRS), infection rates increased for skin and soft tissue, urinary tract, and respiratory tract infections. This continues the trend seen in the 2022 report.
Providing Over-the-Counter Monograph Submissions in Electronic Format July 2024
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/providing-over-counter-monograph-submissions-electronic-format?utm_medium=email&utm_source=govdelivery
FDA issued a final guidance for industry titled “Providing Over-the-Counter Monograph Submissions in Electronic Format.”
The final guidance provides information on providing electronic submissions to FDA under section 505G of the Federal Food, Drug, and Cosmetic Act. These electronic submissions are referred to as over-the-counter (OTC) monograph submissions.
The final guidance is intended to assist submitters by describing the electronic OTC monograph submission requirements and providing recommendations and other information on how to send OTC monograph submissions to FDA in electronic format.
OTC monograph submissions must be submitted electronically, and, depending on the type of submission, should be submitted to FDA through the CDER NextGen Portal, or as specified by the instructions in the OTC Monographs@FDA portal. Submissions related to updating drug listing information should be electronically submitted consistent with the Electronic Drug Registration and Listing System process and instructions.
Changes from the draft guidance to the final guidance are primarily intended to clarify how to submit OTC monograph submissions through the CDER NextGen Portal. In addition, editorial changes were made to improve clarity.
miércoles, 24 de julio de 2024
Evaluating the Immunogenicity Risk of Host Cell Proteins in Follow-On Recombinant Peptide Products
https://www.federalregister.gov/public-inspection/2024-16356/evaluating-the-immunogenicity-risk-of-host-cell-proteins-in-follow-on-recombinant-peptide-products?utm_medium=email&utm_source=govdelivery
Today, FDA issued a Federal Register notice, “Evaluating the Immunogenicity Risk of Host Cell Proteins in Follow-on Recombinant Peptide Products: Establishment of a Public Docket: Request for Information and Comments.”
This notice establishes a public docket seeking substantive comments from interested parties on evaluating the immunogenicity risk of host cell proteins. For the purposes of this request, FDA is specifically interested in comments on suitable methods to detect, identify and control host cell proteins in commercial lots of recombinant peptide products (including information on achievable residual amounts of host cell proteins in the drug product) as well as in vitro, in silico immunogenicity assessment (IVISIA) of host cell proteins in recombinant peptide products.
Although follow-on recombinant peptide products can rely on FDA’s findings of safety and effectiveness for a listed drug that is a peptide product, differences in recombinant expression systems used during the peptide production could result in quality attribute differences, including in the host cell protein profile, which in turn, could contribute to differences in immunogenicity risk between a follow-on peptide product and the relied upon listed drug. Public comments will help FDA develop recommendations for evaluation and mitigation of the immunogenicity risk associated with differences in host cell protein profiles between the follow-on and listed drug.
See the FRN for additional information about this open docket, including what information to include when submitting comments.
Trauma Informed Care
Trauma Informed Care
Evidence was insufficient to draw conclusions about the effects of Trauma Informed Care (TIC) in primary care or psychiatric hospitals for adult patients for any outcome.
Evidence was insufficient to draw conclusions about the effects of TIC in any setting for children or youth patients/clients for any outcome.
TIC models vary considerably in their socioecological components (cultural relevance, training, screening, system embedding) from youth to adult services across settings and disciplines. Current organizational and clinical components encompass a broad range of considerations with only some overlap within both the organizational and clinical domains.
A few models of TIC had specific elements of cultural competence and/or humility (e.g., emphasizing a need to understand patient/client symptoms within the context of life experiences, culture, and historical issues)
Risk Mitigation Using the Anesthesia Risk Alert Program: Applying a Proactive Approach With Data Review & Collaborating With a Second Practitioner
https://psnet.ahrq.gov/innovation/risk-mitigation-using-anesthesia-risk-alert-program-applying-proactive-approach-data
North American Partners in Anesthesia (NAPA) is a nationwide anesthesia practice with more than 450 facilities in 21 states. NAPA employs anesthesiologists, certified registered nurse anesthetists, and certified anesthesiologist assistants. The Anesthesia Risk Alert program is a protocol created as a work product by NAPA’s component Patient Safety Organization, the NAPA Anesthesia Patient Safety Institute (NAPSI), which monitors patients for specific high-risk clinical factors and trains providers to apply targeted mitigation interventions when patients are considered at risk.1 The interventions are based on well-researched practices and clinical guidelines and were informed by an analysis of three years of adverse event data across NAPA by NAPSI, referred to throughout as the innovator. This data analysis revealed five high-risk clinical scenarios. The NAPSI team created a detailed program for providers to respond to each of the five scenarios.
Development of patient safety measures to identify inappropriate diagnosis of common infections.
https://psnet.ahrq.gov/issue/development-patient-safety-measures-identify-inappropriate-diagnosis-common-infections
Misdiagnosis of infections can lead to overuse of antibiotics and threaten patient safety. This article describes the development of two National Quality Forum (NQF)-endorsed measures of inappropriate diagnosis of urinary tract infection (UTI) and community-acquired pneumonia (CAP). Both measures demonstrated strong validity and reliability through testing with patient focus groups and case review. Implementation evaluation across more than 40 Michigan hospitals demonstrated significant decreases in inappropriate diagnoses of UTI and CAP, indicating broad usability of these measures to support improved outcomes.
Systematic review of types of safety incidents and the processes and systems used for safety incident reporting in care homes.
https://psnet.ahrq.gov/issue/systematic-review-types-safety-incidents-and-processes-and-systems-used-safety-incident
Incident reporting systems are commonly used to detect threats to patient safety. This systematic review of 106 studies examined the characteristics of incident reporting processes in residential care facilities and nursing homes in high-income countries. The authors summarize how incidents are detected; common contributing, mitigating, and ameliorating factors; as well as actions and interventions to reduce the risk of patient safety incidents.
A symptom-checker for adult patients visiting an interdisciplinary emergency care center and the safety of patient self-triage: real-life prospective evaluation.
https://psnet.ahrq.gov/issue/symptom-checker-adult-patients-visiting-interdisciplinary-emergency-care-center-and-safety
Patients presenting to the emergency department (ED) are triaged to prioritize care based on level of illness. In this study, 2,543 patients presenting to an ED in Switzerland were asked to self-triage using an electronic symptom-checker. (Patients were triaged and treated based on standard-of-care nurse triage.) Recommendations were given regarding time to treat (e.g., emergency) and point-of-care (e.g., self-care) and subsequently evaluated by three panels of experts. Fifty of the 2,543 patients were judged as undertriaged, but none were judged as potentially hazardous.
AHRQ Papers on Diagnostic Safety Topics
AHRQ Papers on Diagnostic Safety Topics: Diagnostic errors occur in all settings of care, contribute to about 10 percent of patient deaths, and are the primary reason for medical liability claims. AHRQ is the lead Federal agency investing in research to improve diagnostic safety and reduce diagnostic error. AHRQ is currently developing a series of papers on different diagnostic safety issues, which will be released over the next year.
Documenting Diagnosis: Exploring the Impact of Electronic Health Records on Diagnostic Safety
Documenting Diagnosis: Exploring the Impact of Electronic Health Records on Diagnostic Safety: This issue brief reviews the history of documentation legislation, including rules and regulations, and outstanding challenges and best practices to improve documentation. It also identifies future developments and opportunities for improvement, including emerging technology-based strategies to improve the traditional documentation process.
Prospective validation of clinical deterioration predictive models prior to intensive care unit transfer among patients admitted to acute care cardiology wards
https://pubmed.ncbi.nlm.nih.gov/38772399/
An AHRQ-funded study published in Physiological Measurement concluded that a predictive analytics tool called CoMET, developed five years before the COVID-19 pandemic, was very accurate in predicting which patients declined in the hospital during the pandemic. Tested in a randomized controlled trial with more than 10,000 patient visits, the tool accurately predicted significant health declines, primarily due to respiratory issues. The study found that the tool’s predictions remained accurate despite changes in clinical practices over time, including during the pandemic. The analysis underscores the importance of real-world validation for predictive models, researchers concluded.
Using 42 CFR part 2 revisions to integrate substance use disorder treatment information into electronic health records at a safety net health system
https://pubmed.ncbi.nlm.nih.gov/38849888/
Using 42 CFR part 2 revisions to integrate substance use disorder treatment information into electronic health records at a safety net health system. Tillman AR, Bacon E, Bender B, et al.
Clinical Conditions With Frequent, Costly Hospital Readmissions by Payer, 2020 STATISTICAL BRIEF #307 April 2024 H. Joanna Jiang, Ph.D., and Marguerite L. Barrett, M.S.
https://hcup-us.ahrq.gov/reports/statbriefs/sb307-readmissions-2020.jsp
AHRQ Stats: Disorders Commonly Associated With Readmission
Sepsis, heart failure and complications from diabetes were the most common conditions associated with hospital readmissions in 2020, accounting for nearly 20 percent of all adult readmissions.
Environmental Monitoring in Compounding JULY 30, 2024
https://www.fda.gov/drugs/news-events-human-drugs/environmental-monitoring-compounding-07302024?utm_medium=email&utm_source=govdelivery
July 30, 2024 | 2:00 PM - 3:30 PM ET
Attendees will hear an overview of Environmental Monitoring for compounding facilities and the role environmental monitoring plays in ensuring product quality and patient safety. Presenters will discuss the statutory and regulatory requirements for environmental monitoring. FDA also will describe the agency’s expectations for compounding pharmacies (under section 503A) and outsourcing facilities (under section 503B) for environmental monitoring. Finally, FDA will discuss different methods specific to environmental monitoring.
martes, 23 de julio de 2024
An isolated viral load test may generate false positive results for people using long-acting PrEP Analysis from large NIH study offers new insight on clinical utility of current U.S. testing algorithm.
https://www.nih.gov/news-events/news-releases/isolated-viral-load-test-may-generate-false-positive-results-people-using-long-acting-prep
A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.
China–US research collaborations are in decline — this is bad news for everyone
China–US research collaborations are in decline — this is bad news for everyone
Scientists say that the drop in partnerships between the scientific powerhouses will hold back research on priorities such as global warming.
By Gemma Conroy
https://www.nature.com/articles/d41586-024-02046-9?utm_source=Live+Audience&utm_campaign=4f7f28dc60-nature-briefing-daily-20240722&utm_medium=email&utm_term=0_b27a691814-4f7f28dc60-50432164
Safeguarding Health Information: Building Assurance through HIPAA Security 2024
https://www.nist.gov/news-events/events/2024/10/safeguarding-health-information-building-assurance-through-hipaa-security
The U.S. Department of Health and Human Services (HHS) Office for Civil Rights (OCR) and the National Institute of Standards and Technology (NIST) Information Technology Laboratory (ITL) are excited to announce the return of the “Safeguarding Health Information: Building Assurance through HIPAA Security” conference for October 2024. After a 5-year absence, the conference is now returning to Washington, D.C. at the HHS Headquarters.
The conference will explore the current healthcare cybersecurity landscape and the Health Insurance Portability and Accountability Act (HIPAA) Security Rule. This event will highlight the present state of healthcare cybersecurity, and practical strategies, tips, and techniques for implementing the HIPAA Security Rule.
The conference will also offer sessions that explore best practices in managing risks to—and the technical assurance of—electronic health information. Presentations will cover a variety of topics including managing cybersecurity risk and implementing practical cybersecurity solutions, understanding current cybersecurity threats to the healthcare community, cybersecurity considerations for the Internet of Things (IoT) in healthcare environments, updates from federal healthcare agencies, and more.
USAID launches the 2024 Preventing Child and Maternal Deaths Annual Report to Congress
https://www.usaid.gov/PreventingChildAndMaternalDeaths
This year’s report illuminates how the United States’ sustained commitment, financial investment, and responsive programming continues to make major strides in advancing maternal and child survival."
— Dr. Atul Gawande, Assistant Administrator for Global Health
Virtual Public Meeting – Home as a Health Care Hub – Stakeholder Listening Session; July 25, 2024 JULY 25, 2024
Virtual Public Meeting – Home as a Health Care Hub – Stakeholder Listening Session; July 25, 2024
JULY 25, 2024
https://www.fda.gov/medical-devices/medical-devices-news-and-events/virtual-public-meeting-home-health-care-hub-stakeholder-listening-session-july-25-2024-07252024?utm_medium=email&utm_source=govdelivery
Register for the FDA’s Home as a Health Care Hub Virtual Meeting
Later this week, the U.S. Food and Drug Administration (FDA) will host a virtual public meeting to discuss the Home as a Health Care Hub initiative.
During this meeting, we will review the Home as a Health Care Initiative, seek input from the public, and start a dialogue about barriers and opportunities associated with making the home part of the health care system.
Important information for the virtual public meeting:
Date: July 25, 2024
Time: 12:00 p.m. to 4:00 p.m. ET
Registration deadline: July 25, 2024, at 11 a.m. ET
AI disease modelling startup CytoReason to scale up in US The company aims to reach more biotech and pharma companies, increase the speed and accuracy of drug development and benefit patients.
https://www.israel21c.org/ai-disease-modelling-startup-cytoreason-to-scale-up-in-us/
Israeli startup CytoReason, which develops computational disease models for predictive insights, has secured $80 million in funding that will scale up its AI disease models and enable it to establish a hub in the United States.
Three take aways from Tel Aviv’s AI and cybersecurity conferences
Three take aways from Tel Aviv’s AI and cybersecurity conferences
Over nine months into the Gaza war, professionals and a few international visitors are still connecting, building and working to make things happen at a host of AI and cybertech events.
The packed tech conferences, hackathons, and events taking place in the Startup Nation during this challenging time serve as positive indicators of the vitality of the local ecosystem.
https://www.israel21c.org/three-take-aways-from-tel-avivs-ai-and-cybersecurity-conferences/
Can liquid biopsy revolutionize cancer treatment? One innovation in diagnostic technology is paving the way for huge shifts in the way experts diagnose, monitor and treat diseases — especially cancer.
https://www.israel21c.org/can-liquid-biopsy-revolutionize-cancer-treatment/
Back in ancient Greece, medical whiz kids like Hippocrates and Alcmaeon of Croton were hot on the idea that blood, phlegm, yellow bile and black bile — known as the body’s “humors” — held the keys to the kingdom of good health and a long life.
Alcon eyecare leader acquires Israeli glaucoma care company Belkin Vision, founded in 2013, developed an effective first-line laser treatment for glaucoma that is easily accessible to doctors and patients.
https://www.israel21c.org/alcon-eyecare-leader-acquires-israeli-glaucoma-care-company/
Geneva-based Alcon, the world’s largest eye care devices company, has closed deal to acquire Israeli company Belkin Vision for $81 million, including a cash payment of approximately $65 million.
NEW POWDER REMOVES CANCER-CAUSING COMPOUNDS FROM FRIED FOOD Beyond Oil absorbs carcinogenic toxins that build up in reused frying oil at eateries, offering benefits to health and environment.
https://www.israel21c.org/new-powder-removes-cancer-causing-compounds-from-fried-food/
French fries, chicken nuggets, onion rings, eggrolls and other fried favorites in restaurants and cafeterias are cooked in oil that gets reused hundreds of times.
ACI’s Legal, Regulatory, and Compliance Forum on Cosmetics & Personal Care Products – West Coast Edition
https://www.thefdalawblog.com/2024/07/acis-legal-regulatory-and-compliance-forum-on-cosmetics-personal-care-products-west-coast-edition/?utm_source=rss&utm_medium=rss&utm_campaign=acis-legal-regulatory-and-compliance-forum-on-cosmetics-personal-care-products-west-coast-edition
The American Conference Institute (“ACI”) is holding its 2nd West Coast Editionof its Legal, Regulatory, and Compliance Forum on Cosmetics & Personal Care Products from September 25-26 at the Le Meridien Delfina, Santa Monica, California.
2024 CBER Patient and Care Partner Listening Meetings September 20, 2024
Gene therapy has recently emerged as a treatment option for some rare diseases with unmet needs. The FDA approved the first gene therapy in 2017 and 19 gene therapies as of June 2024, many of which are for rare diseases. Clinical trials that support approval of gene therapy products provide the needed information about the risks and benefits of the product so that patients and care partners can make informed decisions regarding treatment.
https://www.fda.gov/news-events/2024-cber-patient-and-care-partner-listening-meetings?utm_medium=email&utm_source=govdelivery
Recommendations for Investigational and Licensed COVID-19 Convalescent Plasma Guidance for Industry JULY 2024
https://www.fda.gov/regulatory-information/search-fda-guidance-documents/recommendations-investigational-and-licensed-covid-19-convalescent-plasma?utm_medium=email&utm_source=govdelivery
What’s New for Biologics
Latest News from the Center for Biologics Evaluation and Research at FDA
https://www.fda.gov/vaccines-blood-biologics/news-events-biologics/whats-new-biologics?utm_medium=email&utm_source=govdelivery
Disease Awareness and Prescription Drug Communications on Television: Evidence for Conflation and Misleading Product Impressions
https://www.fda.gov/drugs/spotlight-cder-science/disease-awareness-and-prescription-drug-communications-television-evidence-conflation-and-misleading?utm_medium=email&utm_source=govdelivery
In this Spotlight on CDER science, CDER researchers conducted two experimental studies among adult asthma patients to determine how the similarity, proximity, and frequency of exposure to a disease awareness communication and prescription drug television advertisement impact consumer perception and understanding of the benefits and risks of a prescription drug. Consumers sometimes conflate the information in disease awareness communications with information presented in prescription drug promotional materials. Previous CDER research has found that conflation occurs when disease awareness and drug promotional materials are viewed in print or on the web. Knowing which advertising features cause conflation is important because it offers an opportunity for pharmaceutical companies to consider these features when developing prescription drug advertising and disease awareness communications.
NIST Announces Funding Opportunity for AI-Focused Manufacturing USA Institute Deadline for submitting concept papers during the first stage of the application process is Sept. 30, 2024. July 22, 2024
https://www.nist.gov/news-events/news/2024/07/nist-announces-funding-opportunity-ai-focused-manufacturing-usa-institute
The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) has announced an open competition for a new Manufacturing USA institute focused on the use of artificial intelligence (AI) to increase the resilience of U.S. manufacturers. The Notice of Funding Opportunity was published today on Grants.gov.
NIST anticipates funding up to $70 million over a five-year period, subject to the availability of federal funds, for the recipient to establish and operate the new institute. The institute will be required to obtain cost-share funds from nonfederal sources.
lunes, 22 de julio de 2024
Stand by Your Case? Without Standing, Supreme Court Precedent Means You’ll Have More Bad Times than Good July 22, 2024 By John W.M. Claud —
https://www.thefdalawblog.com/2024/07/stand-by-your-case-without-standing-supreme-court-precedent-means-youll-have-more-bad-times-than-good/?utm_source=rss&utm_medium=rss&utm_campaign=stand-by-your-case-without-standing-supreme-court-precedent-means-youll-have-more-bad-times-than-good
Sometimes it’s difficult to be a plaintiff, putting all your work into just one case. That’s especially true if recent Supreme Court rulings have rendered your matter a quixotic pursuit, doomed to fail for lack of direct causation.
That’s what happened last week in District Court in Maryland. Following the precedent on standing that the Supreme Court handed down in June in FDA v. Alliance for Hippocratic Medicine et al., a judge in Maryland dismissed another suit against FDA for lack of standing.
Bird flu that infected 6 Colorado poultry workers is closely related to the virus in cows Megan Molteni By Megan Molteni July 22, 2024
https://www.statnews.com/2024/07/22/bird-flu-infects-colorado-poultry-workers-related-to-h5n1-in-cows/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_BdReZOW0twYsVEmcUb6Kd_36RhjPNKR0iKcovxSbpoz73e8RrzyXaT20tmRit1ZtlGY7thC2CAPNs97OlPBHpYNqEEA&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Bird flu Snapshot: Virus that infected 6 people closely related to the one in cows
Public health experts who’ve been following the surprising spillover of bird flu into America’s dairy cattle herds now have all eyes on Colorado, waiting to see if a cluster of human cases there might balloon into something bigger. On July 14, Colorado officials announced that five workers involved in the culling of 1.8 million chickens at a large H5N1-infected egg farm in Weld County had tested positive for the virus. On Friday, the CDC confirmed a sixth case of bird flu among the workers.
The six Colorado cases were all mild, but it’s the first time multiple human cases have been reported on a single farm in the U.S. Read more from STAT’s Megan Molteni on what questions this raises about the virus and how it spreads.
https://cdphe.colorado.gov/press-release/health-officials-confirm-human-cases-of-avian-flu-in-colorado-poultry-workers?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_0unJii_iTEl-S-WAVrcK24nllstzLaypALC_eJWHoeQNoV_HC1Wn2ztoIhTiCFh3aqX9XYUsMLmBDW_oZIwehzuHtcw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
At a Mass General perfusion lab, a push to make more and more hearts viable for transplant Deborah Balthazar By Deborah Balthazar July 22, 2024
https://www.statnews.com/2024/07/22/mass-general-perfusion-lab-heart-transplants/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--4Vcn7pHI9gTP9q7ZmL-KLPCRvwQoEw3CrulijWD1VN6xpXbvCNQlLOTA06dPYQbN3Dhqdw8oqV6B5TDQUdxuj0w6zOw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
There are two holy grails in solid organ transplantation, says surgeon Dominic Emerson. First: Finding a way for transplanted organs to evade rejection. Second: Figuring out how to sustain organs outside of donors and recipients for longer periods of time, and how to rehabilitate them.
At a lab in Boston, researchers are chilling hearts in pursuit of the latter goal. A Mass General Hospital team is working to improve a technique known as organ perfusion — taking an organ that has been kept cold for several hours and reviving it, maintaining the organ outside of the body in a box, and pumping it with blood to keep the tissues alive. Typically, hearts can’t be kept on ice for much more than four hours before the cold wrecks it. But after about a year and a half of work, the MGH team has used their new technique on 57 pig hearts and 11 human hearts that weren’t fit for transplantation. They were even able to reanimate a human heart for six hours, even though it had already been on ice for five to six.
Exhausted by prior auth, many patients abandon care: AMA survey JUL 18, 2024
https://www.ama-assn.org/practice-management/prior-authorization/exhausted-prior-auth-many-patients-abandon-care-ama-survey?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--35uNu61f8MF_BYN_4Mje6NhmJUzz9sCws3V4RByj2KpZGbxF2oJHRAluhBasmthp1aQ1v2kl8Y826LxDBIL_dmoRemg&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Prior authorization hurts patient care: Survey
Seventy-eight percent of physicians say that the prior authorization process “often or sometimes” leads their patients to abandon treatment, according to an AMA survey of 1,000 practicing physicians. Prior authorization requires clinicians to get approval from an insurer to pay for a medication or service before actually providing it.
The vast majority of physicians surveyed (94%) responded that prior authorization sometimes, often, or always delays patients trying to access necessary care. Almost 20% said that prior authorization has resulted in a serious adverse event that hospitalized someone.
The stakes are high and insurers have a lot of power, which is why clinicians were outraged last summer when UnitedHealthcare attempted to instate a prior authorization policy for colonoscopies. Earlier this year, the Biden administration finalized a rule forcing insurance companies to give specific reasons for denying coverage.
https://www.statnews.com/2024/01/17/prior-authorization-health-insurance-white-house/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_aHtyaIlQXAtes4On3S8Du76XrOIine-BqXT10z75LfrXkhABpOwZugZCMPqso4SQhrVZrnUI6ZLaZNum2DsJyH0bJxg&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Microsoft global outage forces health systems to cancel appointments, delay procedures Katie Palmer Brittany Trang Casey Ross By Katie Palmer , Brittany Trang , and Casey Ross July 19, 2024
https://www.statnews.com/2024/07/19/microsoft-crowdstrike-outage-hospitals-cancellations/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_veP7T5cjL6TEUYbkGswhZjIAWuhHdQ7iknOIHC24novGQHYglGcJuu9QZ2_XWmdyzMoLIvX5Hgw1aNvAKt8jGMXzB6A&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Health systems scramble after global outages
A global outage to Microsoft systems disrupted care at health systems across the country Friday, STAT’s health tech team reports. Hospital networks including Mass General Brigham canceled all non-urgent appointments and surgeries. Others, like Cincinnati Children’s, were able to keep a regular schedule, but warned about delays.
The issue seemingly stemmed from a software update by the cybersecurity firm Crowdstrike, which then disabled computers running Microsoft Windows. While the use of Microsoft machines and software is extensive in health care, some systems, like Johns Hopkins Medicine, were not affected.
Studies show that patient outcomes during cyberattacks are worse — and while this outage isn’t a hack, it still cripples many of the same systems. Read more on the latest.
Trump rallies his base on bolstering health care, avoiding thorny questions about health rights Sarah Owermohle By Sarah Owermohle July 19, 2024
https://www.statnews.com/2024/07/19/donald-trump-healthcare-abortion-transgender-medicare-right-to-try/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-94wDMryM81UNkDMt2xAxU3hmiN01idOCntSC3OfymSVsUxT7yyB7RhX06A7D3rP4Zr_wMLqkFmBaMf3m3Y74FvuhOBlw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Trump campaign provides details on his ear wound after rallying the base on health care at the RNC
Former President Donald Trump required no stitches after a gunshot grazed his ear at a campaign rally July 13, his former White House doctor said in a memo released Saturday by Trump’s campaign. The bullet passed less than a quarter inch from the former president’s head, causing a two-centimeter-wide wound and “significant bleeding, followed by marked swelling of the entire upper ear,” Rep. Ronny Jackson (R-Texas) said in the letter. But “given the broad and blunt nature of the wound itself, no sutures were required,” Jackson wrote.
Experts in trauma medicine told STAT earlier last week that the ear was likely to heal and fill in without stitches. The update comes after a week of public appearances at the RNC’s campaign convention, where Trump appeared with a large bandage on his right ear and told attendees that the bullet came perilously close to killing him.
On Thursday night, Trump gave a 90-minute acceptance speech for the Republican nomination to the presidency. While the vast majority of his hour-and-a-half speech rallied convention-goers on the economy, border control, and foreign relations, the former president hit on some health care issues, such as Right to Try legislation, that have polled well with voters even if they have seen little impact so far.
Read more in two stories from STAT’s Sarah Owermohle on how the wound is healing and what health care issues Trump did and didn’t touch in his nomination acceptance speech last week.
https://www.statnews.com/2024/07/17/trump-ear-injury-gunshot-trauma-experts-weigh-in-2/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-9qMiwyny5-Rd-hw30tmB2J9gsXqV5QG01fi2V7xoZgdAlC7OzYnNC_ZjUB_tQ5EzG9ZmCelAa5fiJ_ns9apIfDt7KvIw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Trump campaign provides new details on his ear wound and treatment
Sarah Owermohle
By Sarah Owermohle July 20, 2024
https://www.statnews.com/2024/07/20/trump-ear-former-doctor-ronny-jackson-memo-on-wound-treatment/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--T2Yg3TuhL21eAGP5xjVqo7h5vbuDJ1UvjafCiSljWwuVn8LTOFQ_ZEh40ijaxfsaYLsxC7PkvTCv-wgC_VUK79J4G7g&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Kamala Harris, endorsed by Biden to replace him, is left of the president on health care Rachel Cohrs Zhang Sarah Owermohle By Rachel Cohrs Zhang and Sarah Owermohle July 21, 2024
https://www.statnews.com/2024/07/21/kamala-harris-on-healthcare-abortion-rights-medicare-for-all-drug-price-caps/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz--NK8X7fEyNC2bcnmbts6KcEtxVYbqda-h6vEimhT4TRxYmUlMyKUXwnogyfGoX431aQQyja2ByPOGClaprnhBBHIg0Gw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
President Biden has officially ended his bid for a second term in the White House and endorsed Vice President Kamala Harris to take his place, he announced yesterday. STAT’s DC team reports that while Harris shares similar views as Biden on many issues, she stands left of the president on health care.
Harris has positioned herself as tougher on the industry by endorsing a transition to Medicare for All (though she still envisioned some sort of role for private plans) and calling for more aggressive drug pricing policies than Biden has been willing to employ. But her strongest health care issue by far is her advocacy for reproductive rights following the fall of Roe v. Wade. She was the first vice president to visit an abortion provider. Unlike Biden, who earlier in his political career held anti-abortion views, Harris has been consistent in her support of access to abortions.
Read more from STAT’s Rachel Cohrs Zhang and Sarah Owermohle on Harris’s health care positions, and check out their story on what reproductive rights advocates and others in health and medicine think about Harris. And don’t forget — she’ll only become the official nominee if the party backs her at the convention next month. Read more from STAT’s John Wilkerson and Rachel about the other potential nominees.
https://www.statnews.com/2024/07/21/kamala-harris-health-care-agenda-endorsed-by-abortion-rights-gruops-progressives/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-800FwVivXTAeJ2Iqb2S97hZHno6NfRZEnV2SNS88GoBSwXh2qx_e77YIX3rpBUmn_TSjdi5_yWx-z8ndQaGX7wQVeeoQ&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
Where 3 Democrats who could replace Biden atop the ticket stand on health care
John Wilkerson
Rachel Cohrs Zhang
By John Wilkerson and Rachel Cohrs Zhang July 21, 2024
https://www.statnews.com/2024/07/21/biden-replacements-harris-whitmer-newsom-healthcare/?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-_7fadBYXLcdDVk-d0JdxWI5qIf59A5e2Bp44m4Aujczrv1g5qZ38wE-Q158oV63EYCY7VhTXO7BQ0bOp8S5XMaHNVbpw&_hsmi=316676560&utm_content=316676560&utm_source=hs_email
The Rising Tide: Trends and Challenges of Lung Cancer in Asia Published: July 8, 2024
Lung cancer is a significant public health issue in Asia, representing one of the leading causes of cancer-related mortality. The incidence of both non-small cell lung cancer and small-cell lung cancer in this region is high, driven by high rates of smoking, air pollution, and specific genetic mutations. Despite ongoing research and health-care efforts, the rising incidence and mortality rates of lung cancer pose an urgent challenge for health-care systems across Asia.
In this Series of three Review articles published in eClinicalMedicine, The Lancet Regional Health – Western Pacific, and The Lancet Regional Health – Southeast Asia, Roselle de Guzman and colleagues explore the impact of climate change on lung cancer rates in the region, including screening, early detection, management, and treatment; Yi-Long Wu and colleagues highlight the development of genetic testing technology in the Western Pacific region; and Kumar Prabhash and colleagues examine the unique factors that are associated with lung cancer in Southeast Asian population.
https://www.thelancet.com/series/lung-cancer-asia?dgcid=hubspot_update_feature_infocusoncology_lungcancerasia24_lansea&utm_campaign=update-lansea&utm_medium=email&_hsenc=p2ANqtz-96Coj3hok4mknkNShplGx3lQvPTmVvt6XHdMJbKyQgFUFLUJe7-WVKcmSrQsCwvrGjorQLLvYXXQXRJgOr27aJMSb_4Q&_hsmi=316670270&utm_content=316447178&utm_source=hs_email
IAPAC-Lancet HIV Commission on the future of urban HIV responses
Cities are home to a disproportionate number of many countries’ population of people living with HIV. The future of urban HIV responses is therefore crucial to the future of the global HIV epidemic. The Commission report offers cities and their communities an equity-centred, rights-based framework to guide the future direction of urban HIV responses in line with Sustainable Development Goal (SDG) 3.3 of ending the HIV epidemic by 2030.
https://www.thelancet.com/infographics-do/urban-hiv-responses?dgcid=hubspot_email_conferencealerts_lanhivftc24&utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz--0Bxqx5CdG9mO7hDYtR89lgcuQz0ZRQCVXk3FbNhs-OqIlnifXmkiFh__xkDmXNoPYHcgWBvHs1qTfDbXPG6P1Y6tvFg&_hsmi=316285152&utm_content=316285152&utm_source=hs_email
The IAPAC–Lancet HIV Commission on the future of urban HIV responses Published: July 20, 2024
With urbanisation trends projecting more than twice as many people in the world will be living in urban versus rural settings by 2050, cities have an increasingly important role to play in achieving the health-related Sustainable Development Goals (SDGs), including ending the HIV epidemic by 2030 (SDG 3.3). The International Association of Providers of AIDS Care (IAPAC)–Lancet HIV Commission on the Future of Urban HIV Responses report centres health equity in urban HIV responses, with cross-cutting recommendations made across intersectional domains. Among these domains are the right to health, health system resilience, syndemic conditions and comorbidities, social determinants of health, and data-driven accountability. The report also proposes opportunities to accelerate progress towards SDG 3.3, and more broadly SDG 10 (making cities inclusive, safe, resilient, and sustainable), with the aim of guiding local, national, and international stakeholders in their efforts to optimise urban HIV responses.
https://www.thelancet.com/commissions/urban-hiv-responses?dgcid=hubspot_email_conferencealerts_lanhivftc24&utm_campaign=conferencealerts&utm_medium=email&_hsenc=p2ANqtz-83ILwGKcuP14L-PTkoz0ojfFgNC6b3JOlRCn6YLAZdQSJrNEjcMnluuAoVVAywDj8ej6USKfaPGhjWV4Lo6ZSKRwqtrg&_hsmi=316285152&utm_content=316285152&utm_source=hs_email
Additive Construction – The Path to Standardization II
https://www.nist.gov/news-events/events/2024/08/additive-construction-path-standardization-ii
Join us on August 20th and 21st at the National Cybersecurity Center of Excellence for the 2nd annual in-person, hands-on workshop focusing on standardization for additive construction, or 3D printing with concrete.
Registration closes August 9th so don't delay!
Sponsored by NIST in partnership with the US Army Engineer Research and Development Center (ERDC), the two-day event will drill down on core issues in standards, codes, and design guidelines. Discussions will contribute to the development of a roadmap for standardization of printing and testing methods.
Also, the consortium, Additive Construction by Extrusion (ACE) Consortium, is active on the Federal Register. The Consortium will bring together stakeholders to identify and address gaps in current standards related to materials, methods, structural performance, and engineering design. The Consortium efforts are intended to study the measurement science needs for the successful adoption of ACE by the construction industry, and to identify and propose new standards to address industry needs not met by existing standards. The next meeting will take place at the conclusion of the ACE workshop on the 21st. Followed by ASTM F42.07.07 committee meetings.
Drug Trials Snapshots: DAYBUE (trofinetide)
DAYBUE is a prescription medicine that is used to treat Rett syndrome in adults and children 2 years of age and older.
https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-daybue
Rescue From Above: How Drones May Narrow Emergency Response Times By Michelle Andrews JULY 22, 2024
https://kffhealthnews.org/news/article/drone-emergency-medical-response-times/
Starting in September, if someone in Clemmons, North Carolina, calls 911 to report a cardiac arrest, the first responder on the scene may be a drone carrying an automated external defibrillator, or AED.
Harris, Once Biden’s Voice on Abortion, Would Take an Outspoken Approach to Health By Stephanie Armour and Julie Appleby and Julie Rovner JULY 21, 2024
https://kffhealthnews.org/news/article/kamala-harris-health-agenda-abortion-womens-health-2024-election/
Throughout Joe Biden’s presidency, he leaned on the outspoken former prosecutor and senator he selected as his vice president, Kamala Harris, to be the White House’s voice of unflinching support for reproductive health rights.
domingo, 21 de julio de 2024
Computing cell state discriminates the aberrant hematopoiesis and activated microenvironment in Myelodysplastic syndrome (MDS) through a single cell genomic studyComputing cell state discriminates the aberrant hematopoiesis and activated microenvironment in Myelodysplastic syndrome (MDS) through a single cell genomic study
sábado, 20 de julio de 2024
Journalists Discuss FTC and Supreme Court Actions — And What’s Up With the Bird Flu JULY 13, 2024
https://kffhealthnews.org/news/article/on-air-july-13-2024-ftc-pbm-bird-flu-purdue-pharma/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-9tEHWv9Y45F3KRGU-K77G4f3zJsBEfe0ZSFpu2YHZpBvwE36-WTuwpapEidddRTPiOycWufrEkSrS1XUIRI9qypZfjWA&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Journalists Discuss FTC and Supreme Court Actions — And What’s Up With the Bird Flu
KFF Health News and California Healthline staff made the rounds on national and local media in recent weeks to discuss topical stories. Here’s a collection of their appearances.
Listen to the Latest ‘KFF Health News Minute’ JULY 16, 2024
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Listen to the Latest 'KFF Health News Minute'
"Health Minute" brings original health care and health policy reporting from the KFF Health News newsroom to the airwaves each week.
The Woman Who Beat an $8,000 Hospital Fee SEASON 11, EPISODE 9 JULY 17, 2024
https://kffhealthnews.org/news/podcast/woman-who-beat-hospital-facility-fee/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-8ygZFarbLgnuK9oAv7iXtIM984nfPjEXiozDTjGaBjCShTul6fAMWjkJS3txxvDhqWnBLz6UhaOqvVI7b3l-mbO0KMvw&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
An Arm and a Leg: The Woman Who Beat an $8,000 Hospital Fee
By Dan Weissmann
In this episode of “An Arm and a Leg,” host Dan Weissmann speaks with Georgann Boatright, a patient in Mississippi who was willing to drive to another state to avoid paying a steep fee to her local hospital.
Tennessee Agrees To Remove Sex Workers With HIV From Sex Offender Registry By Brett Kelman JULY 17, 2024
https://kffhealthnews.org/news/article/tennessee-sex-offender-registry-removing-sex-workers-hiv/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-8D4XP9ZMXP6gQxO1VskN6t0p0Fz1xUq1IopNgmeYhEE9j_ahk0_YnYGmamBLr8-JyzPDEq3BRQ7wd3IWgmTWpPTYQgtg&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Tennessee Agrees To Remove Sex Workers With HIV From Sex Offender Registry
By Brett Kelman
For years, Tennessee has required anyone convicted of prostitution while HIV-positive to register as a sex offender for life. To settle DOJ and ACLU discrimination suits, the state has agreed to reverse course.
Before Michigan Legalized Surrogacy, Families Found Ways Around the Ban By Kate Wells, Michigan Public JULY 16, 2024
https://kffhealthnews.org/news/article/michigan-surrogacy-now-legal-parent-strategies/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz--mCtcpbpScukU16YhiAUaTT_X36Smt7dPx5cBl1X00T-4p3134c0d95LNoPXxYFVccmpNEE4bIy9jv2oUk7_h4fPm9aw&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Before Michigan Legalized Surrogacy, Families Found Ways Around the Ban
By Kate Wells, Michigan Public
Until this spring, Michigan was the only state that had a broad criminal ban on surrogacy. Many families say that left them in limbo: forcing them to leave the state to have children, finding strangers on Facebook who would carry their child, or going through the legal hassle of having to adopt their biological children.
Despite Past Storms’ Lessons, Long-Term Care Residents Again Left Powerless By Sandy West JULY 15, 2024
https://kffhealthnews.org/news/article/texas-blackouts-nursing-homes-long-term-care-disaster-preparedness-power-outage-generators/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz--nWUolAOF47uW5GNsl6_EFw2meb7R46Nz6Euv-IkKPjiFxPvx9ddVycnT83aHIjOXiMjEUb-_vfexBKq_0ts3mDZ2d6A&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Despite Past Storms’ Lessons, Long-Term Care Residents Again Left Powerless
By Sandy West
Even after multiple massive power outages — including one from a 2021 winter storm in Texas that prompted a U.S. Senate investigation — little has changed for older Americans in senior living facilities when natural disasters strike.
Colorado Poultry Workers Battle Bird Flu in Heat Wave as US Struggles to Contain Outbreak By Amy Maxmen UPDATED JULY 19, 2024 ORIGINALLY PUBLISHED JULY 15, 2024
https://kffhealthnews.org/news/article/bird-flu-cases-colorado-poultry-workers-virus-spread/
Colorado Poultry Workers Battle Bird Flu in Heat Wave as US Struggles to Contain Outbreak
By Amy Maxmen
So far, all nine cases reported nationally this year at dairy and poultry farms have been mild, consisting of respiratory symptoms and eye irritation. Scientists have warned that the virus could mutate to spread from person to person, like the seasonal flu, and spark a pandemic.
Montana’s Plan To Curb Opioid Overdoses Includes Vending Machines By Mara Silvers, Montana Free Press JULY 18, 2024
https://kffhealthnews.org/news/article/montana-opioid-overdoses-naloxone-narcan-vending-machines/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz--qku5I5qfxSKMWZA2mWUyiifnl5ghA1GypSk20ehViza_grLfDEcXnlLL04iBUu-aLmo7tj-uo6xnyt0bhvppdfD2vhQ&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Montana’s Plan To Curb Opioid Overdoses Includes Vending Machines
By Mara Silvers, Montana Free Press
Details about where the machines would go — and how they would help those most at risk — are sparse. The state has proposed using them to distribute naloxone and fentanyl testing strips.
California Health Care Pioneer Goes National, Girds for Partisan Skirmishes By Samantha Young JULY 15, 2024California Health Care Pioneer Goes National, Girds for Partisan Skirmishes By Samantha Young JULY 15, 2024
https://kffhealthnews.org/news/article/anthony-wright-qa-families-usa-health-policy/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-9lR08CZO4WeEIYsu2rFDQGCGoDLAI6cQTBUCuZupfkxRODP5TDks_OTLnCZDUXCArwo3lTm7zfzXXX0FoHSHcC3FTWzg&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
California Health Care Pioneer Goes National, Girds for Partisan Skirmishes
By Samantha Young
Anthony Wright, a champion for Californians’ health care rights, will take the helm of Families USA in Washington, D.C., where he plans to campaign for more affordable and accessible care nationally. He leaves Health Access California, where he helped outlaw surprise medical billing, require companies to report drug price increases, and cap hospital bills for uninsured patients.
HealthSherpa and Insurers Team Up To Curb Unauthorized ACA Enrollment Schemes By Julie Appleby JULY 16, 2024
https://kffhealthnews.org/news/article/healthsherpa-insurance-unauthorized-obamacare-signups/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-8znNakCyVDbdS0tpq5WaMAts6Z4FmP39AsfKYEMbcaBs8-j2UZtrPEBnNIdIpWFt31UxVjH6NPGNSQDP3zE0qcdV8HJg&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
HealthSherpa and Insurers Team Up To Curb Unauthorized ACA Enrollment Schemes
By Julie Appleby
The initiative targets the biggest incentive driving fraudulent sign-ups and plan switches: the commissions that rogue agents or large call centers seek
Misleading Ads Play Key Role in Schemes to Gin Up Unauthorized ACA Sign-Ups, Lawsuit Alleges By Julie Appleby JULY 19, 2024
https://kffhealthnews.org/news/article/aca-fraud-misleading-ads-unauthorized-signups-switches-obamacare/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-8J28QG3pADroj8joksdZ1zJhb4bfOxOwxBwCHkdyElJ_1N_V-1vu5jXOUU0Ay6CwLlOfKAxFSS7k_agKzZs0aMsZinLQ&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Misleading Ads Play Key Role in Schemes to Gin Up Unauthorized ACA Sign-Ups, Lawsuit Alleges
By Julie Appleby
Misleading money-for-groceries ads helped lure people to call centers where some were enrolled in Affordable Care Act coverage — or switched from their existing plans — without their express permission, a new lawsuit alleges.
The Nation’s 911 System Is on the Brink of Its Own Emergency By Stephanie Armour JULY 17, 2024
https://kffhealthnews.org/news/article/911-outages-emergency-response-cellphone/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-89uGJL51yGBavCXT_tbfoUIJ3nK4CFnVp56xt95FzRYZ4j2GVFp8rgYrDCtXIPbUvQUMbWE2Ce7c6eTtNT9_BO4bbO2w&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
The Nation’s 911 System Is on the Brink of Its Own Emergency
By Stephanie Armour
911 outages have hit at least eight states this year. They’re emblematic of problems plaguing emergency response communications due in part to wide disparities in capabilities and funding.
Rural Hospitals Built During Baby Boom Now Face Baby Bust By Tony Leys JULY 15, 2024
https://kffhealthnews.org/news/article/rural-hospitals-obstetrics-gynecology-birth-decline-labor-delivery/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-8WlQcrmzo6qMLff1pAxeIXesMTYWX5LXChBmdZtloqTxlVx-qIkR8eKziVNm8VBvunYAK9JXYH1_hiPA001y6kOOBE2g&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
Rural Hospitals Built During Baby Boom Now Face Baby Bust
By Tony Leys
Fewer than half of rural U.S. hospitals offer labor and delivery services. In some areas, births have dropped by three-quarters since the baby boom’s peak.
A California Medical Group Treats Only Homeless Patients — And Makes Money Doing It By Angela Hart JULY 19, 2024
https://kffhealthnews.org/news/article/california-homeless-medical-care-healthcare-in-action/?utm_campaign=KHN%20-%20Weekly%20Edition&utm_medium=email&_hsenc=p2ANqtz-_FU6udQE1D9cY7yvmz2aPm5sNTxhH-0ebNHCpVnnefPUAE0tKN00fYXi0W8NVZIHvp9k1DRRku-W7I-BEI37OMSQ6THg&_hsmi=316539109&utm_content=316539109&utm_source=hs_email
A California Medical Group Treats Only Homeless Patients — And Makes Money Doing It
By Angela Hart
Healthcare in Action, a California medical group that exclusively serves homeless people, has tapped into growing demand and funding for street medicine services. Three years in, the innovative nonprofit is raking in revenue and serving thousands of people who otherwise might flock to the hospital for high-cost care.
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