Identification of dynamic microbiota signatures in patients with melanoma receiving ICIs: opportunities and challenges

https://pubmed.ncbi.nlm.nih.gov/38509333/ From the abstract: "The composition of the gut microbiota has emerged as a tumour-extrinsic factor that modulates response to immune-checkpoint inhibitors (ICIs), although the lack of consistency in microbiota signatures across studies has limited their value as reliable biomarkers. Herein, we discuss a recent study in which longitudinal microbiome profiling identified several taxa that are persistently enriched in patients with melanoma and a favourable response to ICIs. "