https://www.statnews.com/2020/07/09/how-does-exercise-benefit-the-aging-brain-transfusing-blood-from-active-mice-into-sedentary-ones-suggests-an-answer/?utm_source=STAT+Newsletters&utm_campaign=b9d134f6c6-MR_COPY_01&utm_medium=email&utm_term=0_8cab1d7961-b9d134f6c6-149692869

Inside STAT: Transfusing blood from active mice into sedentary ones to study exercise and aging

(HYACINTH EMPINADO/STAT)

The latest in a series of "young blood" experiments — where blood from younger subjects is transfused into older subjects in an effort to stall aging and related diseases — has found that a single protein found in the liver may explain why exercise may help restore some of the effects of aging in the brain. Prior to a transfusion, sedentary mice had trouble finding a platform hidden in water compared to more active mice. But after getting a transfusion of blood from younger, more active mice, the sedentary mice were able to find the platform just as well. And higher level of the liver protein — called GPLD1 — corresponded with higher cognitive function in the mice. Read more from STAT's Theresa Gaffney here.