Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review

Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review: The goal of this systematic review is to identify peer-reviewed, published research available since the last joint DRI for macronutrients guidelines were established regarding effects of total fat and PUFAs on birth outcomes, growth and development, and neurocognitive outcomes in generally healthy populations at different life stages. This review will enable the alignment of dietary recommendations with the most current and comprehensive evidence, ensuring that current recommendations lead to health and lifestyle behaviors that enhance pregnancy outcomes and optimize offspring physical growth and cognitive development from conception through adolescence, promoting long-term health and wellbeing. Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: A Systematic Review (Available for comment until September 29, 2025) To support possible updates and expansion the 2005 U.S.-Canadian Dietary Reference Intakes (DRIs), this systematic review was designed to identify and summarize the evidence on the relationships between: Consumption of omega-6 and/or omega-3 (n-6 and n-3) polyunsaturated fatty acids (PUFAs) during pregnancy and risk of preterm birth Intake during pregnancy and/or lactation and infant and child growth and development, and Intake of total fat or n-6 and/or n-3 PUFA by children between birth through 18 years of age and growth and developmental outcomes.