Global study reveals disparities in early-onset gastric cancer

https://www.news-medical.net/news/20260216/Global-study-reveals-disparities-in-early-onset-gastric-cancer.aspx Gastric cancer remains the fifth leading cause of cancer-related deaths worldwide. Although its overall incidence has declined, early-onset cases—diagnosed before age 50—display unique biological and clinical patterns. These include diffuse histologic features, signet ring cell predominance, and poor prognosis. Environmental and lifestyle exposures, such as Helicobacter pylori infection, smoking, and high-salt diets, are known contributors. However, previous global studies have rarely focused exclusively on early-onset gastric cancer(EOGC). Due to these challenges, it is necessary to conduct in-depth research on the global distribution, risk factors, and future trends of EOGC to inform effective prevention