martes, 26 de mayo de 2020

Covid-19 study details benefits of remdesivir treatment, and also limitations

Covid-19 study details benefits of remdesivir treatment, and also limitations

Morning Rounds

Shraddha Chakradhar

The latest on Covid-19 drugs and vaccines

The Friday evening before a holiday weekend is traditionally when groups release news they would rather no one pay attention to. But this past Friday, we finally got the full data from the NIH-run study showing that Gilead's remdesivir sped the recoveries of people with Covid-19. The data also revealed that the drug had a more limited benefit for patients who were severely ill, underscoring the need for additional treatments — as well as vaccines. More here
  • After a study on Friday found that hydroxychloroquine was associated with higher mortality in Covid-19 patients, the WHO said Monday it had paused enrollment in the hydroxychloroquine portion of its multiarm Solidarity Trial to review the safety and efficacy data generated so far.
  • In vaccine news, data from a candidate being developed by the Chinese drug maker CanSino showed that it induced an immune response in participants, but that some had a weak response because of their interaction with a component of the vaccine. Separately, a participant in the Moderna vaccine trial tells STAT about experiencing a severe reaction after being dosed with the vaccine. 
  • The Trump administration has tapped Janet Woodcock, a respected FDA veteran, to work full time on the White House's Covid-19 vaccine efforts. It may sound like a wonky personnel move, but it's a signal of the pressure to develop a vaccine.
  • The administration also sent its strategic testing plan to Congress this weekend, putting a bulk of the responsibility on states.

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