jueves, 25 de junio de 2020

Yumanity Therapeutics, Merck strike deal aimed at developing new medicines for neurodegenerative disease

https://www.statnews.com/2020/06/24/yumanity-therapeutics-merck-strike-deal-aimed-at-developing-new-medicines-for-neurodegenerative-disease/?utm_source=STAT+Newsletters&utm_campaign=dcb05195f8-RO_COPY_04&utm_medium=email&utm_term=0_8cab1d7961-dcb05195f8-149692869
The Readout
Damian Garde & Meghana Keshavan

Three years after failing in Alzheimer’s, Merck is investing more in neuroscience

Back 2017, the decisive failure of a Merck drug called verubecestat helped bring about the end of an entire wing of Alzheimer’s disease research. Now, Merck is gradually building back a neuroscience pipeline, partnering with a startup on some early-stage projects.

As STAT’s Adam Feuerstein reports, Merck signed a deal with Yumanity Therapeutics in hopes of finding novel treatments for amyotrophic lateral sclerosis, or ALS, and frontotemporal lobar dementia, a group of related conditions resulting from the degeneration of brain cells.

Yumanity, founded in 2014 by biotech entrepreneur Tony Coles, is building on the discoveries of Susan Lindquist, a well-known researcher and National Medal of Science recipient who used yeast as a model organism to study neurodegenerative diseases caused by misfolded proteins.

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