jueves, 6 de agosto de 2020

Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects | Congenital Defects | JAMA Psychiatry | JAMA Network

Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects | Congenital Defects | JAMA Psychiatry | JAMA Network

Morning Rounds

Shraddha Chakradhar

Use of a common antidepressant during pregnancy could lead to birth defects in newborns

Expectant mothers who use a common antidepressant during pregnancy may be likelier to deliver babies with birth defects, according to a new study. Up to 8% of pregnant women are prescribed antidepressants, and scientists in recent years have sought to understand how these drugs affect infants. And while birth defects are rare, venlafaxine, or Effexor, was linked with the most birth defects, including congenital heart defects. This association existed even after the scientists accounted for other underlying conditions. The study used data from two groups of U.S. women — over 1,500 mothers of babies with birth defects, and nearly 500 mothers of infants without congenital defects — who used one of six common antidepressants. The study doesn't establish cause and effect, so more research is needed to determine the role of specific antidepressants on birth defects.

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