Large language model influence on diagnostic reasoning: a randomized clinical trial. November 13, 2024

https://psnet.ahrq.gov/issue/large-language-model-influence-diagnostic-reasoning-randomized-clinical-trial Large language model influence on diagnostic reasoning: a randomized clinical trial. Goh E, Gallo R, Hom J, et al. JAMA Netw Open. 2024;7(10):e2440969. Large language models (LLM) offer a promising approach to improving diagnostic accuracy. In this study, internal medicine physicians were randomized to use conventional (eg, UpToDate) or conventional plus LLM diagnostic resources to provide a differential and final diagnosis on 4 to 6 clinical vignettes. There was no significant difference in diagnostic performance or time spent per case between conventional and conventional plus LLM groups; LLM alone performed 16% better than the control group.