miércoles, 11 de septiembre de 2019

At last, lots of liquid biopsy data exists

The Readout
Damian Garde

At last, lots of liquid biopsy data exists

After years of skepticism, liquid biopsy companies are creating a wave of actual, published data. 

Personal Genome Diagnostics, a Maryland-based company, is the latest to publish its own. The company has a new paper out in Clinical Cancer Research showing that its blood test can identify a key characteristic of tumors that’s normally only discernible with a biopsy. 
One of the two biomarkers the test tries to detect is “microsatellite instability,” or MSI-High — which is used to predict whether a person’s tumor could respond to immunotherapies like Keytruda. Guardant Health published its own data on a similar test last month; Grail presented its data on a blood test meant for screening healthy people in May.

Personal Genome, which has received funding from New Enterprise Associates and Bristol-Myers Squibb, has some familiar faces among its founding advisors. Three of the scientists behind Thrive Earlier Detection Corp, another venture-backed liquid biopsy company, also serve on PGDx’s board

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