miércoles, 26 de agosto de 2020

Catdesivir is finally getting a chance in Covid-19

The Readout
Damian Garde & Meghana Keshavan

Catdesivir is finally getting a chance in Covid-19

A close molecular cousin to Gilead Sciences’ remdesivir, which has long been used to treat a different coronavirus in cats, will soon be tested as a treatment for Covid-19, following months of advocacy from independent scientists.

As STAT’s Ed Silverman reports, researchers at the NIH are moving forward with GS-441524, an antiviral compound that, in lab tests, appears to replicate remdesivir’s effects on Covid-19 with less toxicity. The drug is also easier to synthesize, which might make it a viable oral treatment. Remdesivir is administered intravenously.

Whether GS-441524 pans out remains to be seen, but the NIH’s decision is a victory for the MD Anderson Cancer Center, which had been pressuring Gilead to advance the compound into clinical trials.

Read more.

No hay comentarios: