Risk of bleeding with concomitant use of oral anticoagulants and aspirin: A systematic review and meta-analysis

https://pubmed.ncbi.nlm.nih.gov/38263263/ Patients are at higher risk of excessive bleeding when taking both blood thinners and aspirin together, according to an AHRQ-funded study published in American Journal of Health-System Pharmacy. Researchers reviewed 42 published studies and found that patients who took both oral anticoagulant medications (which are blood thinners such as warfarin) and aspirin had a higher chance of bleeding compared with those only taking blood thinners. Warfarin is prescribed for stroke prevention in atrial fibrillation and for treatment and secondary prevention of venous thromboembolism, while aspirin may still be used to prevent primary cardiovascular events among high-risk patients.