The unintended consequences of the Lindsay Clancy case How fear of liability could affect psychiatric care of mothers

https://www.statnews.com/2026/08/28/lindsay-clancy-postpartum-psychosis-reproductive-psychiatrists-liability/ By Renee Sorrentino and Susan Hatters FriedmanAug. 28, 2026 Sorrentino is a forensic psychiatrist in Boston. She is president-elect of the American Academy of Psychiatry and the Law. Friedman is a forensic and reproductive psychiatrist at Case Western Reserve University. She is past president of the American Academy of Psychiatry and the Law.

Juul gets OK to sell updated vaping device with age-gating technology In recent years, company has paid roughly $3 billion to settle lawsuits over teen use of its products

https://www.statnews.com/2026/08/28/juul-fda-clearance-updated-ecigarette-age-gating-technology/ By Associated PressAug. 28, 2026

FDA approves Protagonist and Takeda’s drug for rare blood cancer Mimrylo, a weekly injection, is a new kind of treatment for polycythemia vera By Adam FeuersteinAug. 30, 2026 Senior Writer, Biotech

https://www.statnews.com/2026/08/30/fda-approves-mimrylo-takeda-protagonist-treatment-for-polycythemia-vera/

EASD 2026 Abstract 97 Global estimates of past, present and future type 1 diabetes incidence, prevalence and mortality: the DIAMOND-T1D model

2.7 million That’s how many more people around the world will be living with type 1 diabetes by 2049. In the U.S., that means an increase of more than half a million cases, topping out at 2,055,235. The global estimate, presented Friday at the annual meeting of the European Association for the Study of Diabetes in Milan, reflects a 29% jump from 9.4 million in 2025 to 12.1 million near the mid-century mark. New cases per year, projected to grow by 14%, are rising more sharply in low-income countries, but absolute numbers remain higher in high-income countries. The researchers say those differences likely stem from a combination of genetics, environmental triggers, and higher case-detection rates in high-income countries. https://drive.google.com/file/d/1Zip9nGloBl1t3_APTfx5EJ-VirDGVxOp/view?_hsenc=p2ANqtz-_Vkq1hC9Ul3zaH7gZZp6ZP-K4d9BIet4LLpYcpjmYvLTJ9fCycfSxmfjRjm86UjWYdgLmy_BwijGD4dYr_Dunfo5D3Rw&_hsmi=435905713

Alnylam defends heart disease drugs after failure of AstraZeneca’s Wainua Biotech argues that it medicines maintain their value, and that a key trial has a better design

https://www.statnews.com/2026/08/30/alnylam-attr-astrazeneca-wainua-attruby-heart-disease/ By Andrew JosephAug. 30, 2026 Europe Correspondent Can a pregnancy hormone steer a cardiovascular treatment? The pregnancy hormone relaxin has long been studied as a potential avenue for a cardiovascular treatment because it can cause blood vessels to widen and relax. One snag has been that high doses of relaxin-related drugs have come with safety issues. AstraZeneca thinks it may have an advantage with its oral relaxin agonist AZD5462. The drug provides a lower dose than older injectable and intravenous formulations, and has now shown hints that it could be an effective medicine, according to midstage trial results presented over the weekend at the European Society of Cardiology’s annual conference. The Phase 2 LUMINARA study tested different doses of AZD5462 in patients with different kinds of heart failure, one known as HFrEF and another as HFpEF, which are distinguished based on how well the heart can still pump blood. The aim of the study was to help investigators figure out what a potential Phase 3 study, which would test clinical outcomes, should look like. Overall, based on a measure of cardiac function, investigators found the drug showed promise, particularly in patients with HFrEF. One nagging issue: A lower dose led to more dramatic effects. “We see positive signals, particularly in rEF patients, on some of the cardiac function metrics that clue us into, would it be effective as a heart failure therapy?” AstraZeneca’s Mina Makar told STAT. “And so we think it has the right combination of efficacy and safety, and now we need to make some decisions as to if we progress it and how we progress it.” For now, AstraZeneca hasn’t detailed any Phase 3 development plans.

We’re reading about drug pricing deals, a new cancer therapy approval, and more Meanwhile, BioNTech has terminated a Phase 2 trial for its colon cancer vaccine

https://www.statnews.com/pharmalot/2026/08/31/drug-pricing-deals-polycythemia-vera-mimrylo-pharmalittle-newsletter/ By Jason MastAug. 31, 2026 General Assignment Reporter

A Novartis drug cut inflammation. Can it improve heart outcomes? The drug, pacibekitug, targets IL-6, a common inflammatory driver By Andrew JosephAug. 29, 2026 Europe Correspondent

https://www.statnews.com/2026/08/29/novartis-pacibekitug-inflammation-il6-tourmaline-heart-disease/?utm_campaign=the_readout&utm_medium=email&_hsenc=p2ANqtz--H7l184vsuRf3xjj77PtzXOzKgOvfz7YmHF21zNAxCsoXPNhrCrlCzFB6GmBDZa0t0rREj0gFvkuqZcwBUrOixNivK7w&_hsmi=436067550&utm_content=436067550&utm_source=hs_email Novartis inflammation drug clears an early hurdle A newly acquired Novartis drug notably reduced inflammation in a midstage study — but whether that will translate into fewer heart attacks and strokes is still an open question, STAT’s Andrew Joseph writes. Pacibekitug, an antibody targeting the inflammatory protein IL-6, was the centerpiece of Novartis’ $1.4 billion acquisition of Tourmaline Bio last year. It lowered levels of hsCRP, a cardiovascular risk marker, by 76% to 89% after 180 days, compared with a 7% increase among patients on placebo, accordingly to newly released data. But the results come with a caveat: Novo Nordisk’s rival IL-6 drug recently failed a pivotal cardiovascular trial despite similarly lowering inflammation. To determine whether this particular pathway actually improves outcomes, Novartis says it is planning a Phase 3 cardiovascular outcomes program. The drugmakers hasn’t yet disclosed which patients it will target.

The most shocking thing about the latest statistics on CTE in football is that we find them so shocking Since its earliest days, it’s been clear football is bad for the brain

https://www.statnews.com/2026/08/31/cte-nfl-boston-university-study-football-concussion-history/ By Emily HarrisonAug. 31, 2026 Harrison is a historian of science and public health at Wellesley College. A new study led by Boston-area researchers has set my media feeds abuzz with the finding that nearly 1 in 4 NFL players in their sample had CTE at time of death. CTE, or chronic traumatic encephalopathy, is a degenerative brain disease. It is caused by repeated concussions and smaller non-concussive hits.

Biotech’s bold new mandate: Breakthroughs beyond the lab Benches and bedsides can feel worlds apart, but technology and AI are closing the distance

https://www.statnews.com/sponsor/2026/08/31/biotechs-bold-new-mandate-breakthroughs-beyond-the-lab/

Cadre of radiopharmaceuticals experts pushes the bounds in cancer therapy Some researchers believe the pharma industry is being too cautious in the face of safety concerns

https://www.statnews.com/2026/08/31/radiopharmaceuticals-dosing-pushing-bounds-cancer-treatment/ By Allison DeAngelisAug. 31, 2026 Biotech Startups and Venture Capital Reporter Radiopharma researchers want bolder dosing Radiopharmaceuticals are powerful new tools in oncology. But are providers maximizing their potential? A small cadre of researchers believes that developers of these therapies may be sacrificing some efficacy by being overly cautious about dosing, STAT’s Allison DeAngelis writes. Among them is Louise Emmett, a leading nuclear medicine researcher in Australia, who is testing whether prostate cancer patients can safely receive radioactive drugs much more frequently than the six- or eight-week intervals typically used today — schedules partly inherited from decades-old external-beam radiation practices. “I'm interested in how we actually improve survival in our patients, not the toxicities,” Emmett said. Safety concerns with radiopharmaceuticals are real — and have led at least one company in the field to shut down recently. But early results suggest Emmitt’s approach can lower cancer markers without significant kidney or other healthy-tissue toxicity. Companies like Telix and AdvanCell are now exploring similarly aggressive dosing schedules.

After a rough stretch, mRNA gets a boost — at least for now Experts hope the success of a cancer vaccine using the technology can rehabilitate the field By Angus ChenAug. 31, 2026 Cancer Reporter

https://www.statnews.com/2026/08/31/mrna-cancer-vaccine-intersects-politics-medicine/ Can cancer vaccines thaw skepticism of mRNA? After years of political backlash against mRNA vaccines, the field’s researchers believe Moderna and Merck’s positive cancer vaccine readout might help turn the tides for the technology — and perhaps even soften some of the broader stigma around vaccines. That stigma has had real consequences: The Trump administration pulled back hundreds of millions of dollars for mRNA research in infectious diseases, and some cancer vaccine companies have actually stopped using the word “vaccine” altogether. But the approval of the Moderna-Merck therapy could open the door to a much broader wave of cancer vaccines, including personalized products as well as off-the-shelf shots targeting common cancer proteins like KRAS or HPV. And mRNA, which can be rapidly programmed to produce different proteins, may be particularly well suited to the task. “I don’t know how this will be received among parts of our society that have become suspicious of the word ‘vaccine.’ There’s a possibility that people will say, ‘Oh, if we can vaccinate against cancer, that’s good,’” said Ryan Sullivan, a Mass General Brigham melanoma physician and immunologist who has worked with Moderna. “Maybe that will thaw some of the stigma around vaccines. I don’t think it’ll fix all of it, but maybe just a little bit helps us think of ‘vaccine’ not as a dirty word, ‘mRNA’ as not a four-letter word.” https://www.statnews.com/2026/08/19/mrna-cancer-vaccine-trial-melanoma-merck-moderna/?utm_campaign=the_readout&utm_medium=email&_hsenc=p2ANqtz-_d9XAbIwD84KLgIzPkSk9ZszRpaM94ZuvFaoZ1jZZFzOYkmevUzMoJgEUg7qcin9Eh7czCX9et_dHta6sesBHn73IAwQ&_hsmi=436067550&utm_content=436067550&utm_source=hs_email

The perfect cookie? 3D-printed cookies made from upcycled plastic waste The Guardian | August 31, 2026

https://geneticliteracyproject.org/2026/08/31/the-perfect-cookie-3d-printed-cookies-made-from-upcycled-plastic-waste/ Scientists at Southern Illinois University Carbondale have found a way to turn plastic bottles and crop waste into protein-rich cookies, an unlikely fix for feeding astronauts on long missions, reports Hannah Devlin for The Guardian.

It’s not child’s play: Teaching a computer to use language requires an inhuman amount of data—and it still learns much more slowly than kids MIT Technology Review | August 31, 2026

https://geneticliteracyproject.org/2026/08/31/its-not-childs-play-teaching-a-computer-to-use-language-requires-an-inhuman-amount-of-data-and-it-still-learns-much-more-slowly-than-kids/ Chatting naturally with a computer now feels routine, but as MIT Technology Review’s Elise Cutts reports, the large language models behind that fluency are shockingly data-hungry compared to human toddlers. Meta’s Llama 3.1 trained on 15 trillion tokens; a preteen raised in a language-rich home hears something like 100 million words. “We still have to burn down a forest and scrape the entire sum of all human knowledge to re-create this milestone that happens in our living rooms over the course of a year,” says Stanford cognitive scientist Michael Frank.

Kennedy’s HHS set to define ultra-processed foods—but will the slippery designation make scientific sense? The Atlantic | August 31, 2026

https://geneticliteracyproject.org/2026/08/31/kennedys-hhs-set-to-define-ultra-processed-foods-but-will-the-slippery-designation-make-scientific-sense/ The federal government is about to attempt what nutrition scientists haven’t managed: a workable definition of “ultra-processed food.” HHS Secretary Robert F. Kennedy Jr. announced his department is finalizing the first official U.S. definition, as Nicholas Florko for The Atlantic reports, though the wording remains under White House review.

Rising costs of fertilizer, fuel, and machinery: Tariffs and stalled Iran war weigh heavily on American farmers Washington Post | August 31, 2026

https://geneticliteracyproject.org/2026/08/31/rising-costs-of-fertilizer-fuel-and-machinery-tariffs-and-stalled-iran-war-weigh-heavily-on-american-farmers/ American farmers are staring down what one Iowa grower calls “another farm crisis,” as President Trump’s tariffs and his war with Iran drive up fertilizer, fuel and machinery costs while crop prices stay weak, the Washington Post’s Jarrell Dillard reports.

Viewpoint: Follow the money: How Bloomberg Philanthropies and the NGO Lighthouse Reports manufactured a Big Food safety scandal David Zaruk | August 31, 2026

https://geneticliteracyproject.org/2026/08/31/viewpoint-heres-how-bloomberg-philanthropies-funded-lighthouse-reports-cynically-twisted-the-data-to-prove-big-food-is-trying-to-block-safety-measures/ What happens when you want to run a campaign, but you have very limited data and evidence? One strategy more increasingly used is to hire an activist NGO like Lighthouse Reports to fabricate an investigation they can funnel through their tried and tested noise machine. What happens if the budget has been cleared but there is no story? No problem. Lighthouse Reports has experienced spinmeisters capable of communicating insignificant research like it was a groundbreaking exposé. Just pay the Dutch NGO enough and they’ll deliver?

The destruction of healthcare in armed conflict: policy implications and accountability Athena Madan* [1]

https://www.academia.edu/3070-3530/3/2/10.20935/AcadMedHealth8372 This Perspective examines how the destruction of healthcare systems in armed conflict produces enduring public health harm and broad human insecurity. Drawing on social medicine, sociological theory, governance scholarship, and field observations from Afghanistan, it argues that attacks on healthcare infrastructure and personnel result in not only the loss of clinical services but also in the erosion of social and moral worlds of care. The paper advances three interrelated claims: first, that healthcare institutions function both as clinical and social infrastructures; second, that their destruction generates disproportionate psychosocial, gendered, and intergenerational harms extending far beyond immediate morbidity and mortality; and third, that the persistence of such attacks reflects abject failures in international protection and accountability mechanisms. Particular attention is given to the consequences for women and children, including preventable death, disability, and psychosocial distress with constrained possibilities for recovery and social ways of belonging. These harms are compounded by weakened international accountability, which has increasingly normalised attacks on healthcare as a feature of war rather than a violation demanding intervention. https://www.academia.edu/journals/academia-medicine-and-health/articles?source=journal-top-nav

Why reproducibility remains a challenge in preclinical research

Improving reproducibility requires more than stronger statistics alone. Across the research community, scientists are adopting new approaches to increase transparency, standardization, and rigor at every stage of the experimental workflow. Read this article to explore emerging strategies for strengthening reproducibility and building more robust preclinical studies. https://www.drugdiscoverynews.com/why-reproducibility-remains-a-challenge-in-preclinical-research-17198?utm_campaign=DDN%20Lead%20Generation&utm_medium=email&_hsenc=p2ANqtz-9SqHrV_7KQATNvLY977Pj57WOQGa71BxP4K1ICIj-HzN5Oc6GJ5egjQe9NsWqD67p_xHh_goN_nn0cH1rxU3PtIwHdjw&_hsmi=435425482&utm_content=435425482&utm_source=hs_email

From absorption to metabolism: predicting human oral drug exposure Tuesday, October 6th 2026 | 10:00 AM – 11:30 AM Eastern Time

From absorption to metabolism: predicting human oral drug exposure Explore how human gut-liver models can improve the translation of preclinical findings into clinical pharmacokinetic predictions. https://www.drugdiscoverynews.com/from-absorption-to-metabolism-predicting-human-oral-drug-exposure-17471?utm_campaign=DDN%20Webinars&utm_medium=email&_hsenc=p2ANqtz-_dEGVAc8X1XZ0yNk8I_gP_EeflCN6OCpSrkcgYOoBe6LC_0RlNKJYeGwRazUpCyvQ9_IyfaBjg7KAHnrNezp7ziSLjWA&_hsmi=435582994&utm_content=435582994&utm_source=hs_email Predicting human oral drug exposure remains a major challenge in preclinical drug development. Intestinal absorption, first-pass metabolism, and drug-drug interactions can all influence systemic exposure, while conventional in vitro and animal models may not fully capture the interplay between these processes. In this webinar, Yassen Abbas and Joseph Broomfield will discuss how integrated gut-liver microphysiological systems (MPS) can provide mechanistic insights into oral drug disposition, including bioavailability, metabolic variability, and drug-drug interactions. They will also explore how MPS data can support physiologically based pharmacokinetic modeling and improve translation to clinical studies. Topics to be covered: Modeling oral drug absorption, metabolism, and bioavailability Improving translation from preclinical studies to humans Identifying drug-drug interactions and their underlying mechanisms Understanding how metabolic variability affects drug exposure and dosing Tuesday, October 6th 2026 | 10:00 AM – 11:30 AM Eastern Time

ACI’s 6th Annual Passport to Proficiency on the Essentials of Hatch-Waxman and BPCIA August 30, 2026

https://www.thefdalawblog.com/2026/08/acis-6th-annual-passport-to-proficiency-on-the-essentials-of-hatch-waxman-and-bpcia/?utm_source=rss&utm_medium=rss&utm_campaign=acis-6th-annual-passport-to-proficiency-on-the-essentials-of-hatch-waxman-and-bpcia The American Conference Institute’s (ACI’s) virtual 6th Annual Passport to Proficiency on the Essentials of Hatch-Waxman and BPCIA is scheduled to take place from October 20-29, 2026 (Eastern Standard Time). Led by an experienced faculty, the virtual training series is specifically designed for attorneys, regulatory affairs professionals, and industry executives working at the intersection of FDA law, IP strategy, and biopharmaceutical innovation to provide advanced training on the 1984 Hatch-Waxman and the 2010 Biologics Price Competition and Innovation Act (BPCIA). And the 2026 program has been refined, condensed, and refreshed to deliver an even more practical and efficient learning experience.

Former Stanford president releases emails to rebut fraud and cover-up allegations in new book Marc Tessier-Lavigne denies claims in Theo Baker’s book that a 2009 study had fabricated results By Jonathan WosenAug. 27, 2026

Former Stanford president releases emails to rebut fraud and cover-up allegations in new book Marc Tessier-Lavigne denies claims in Theo Baker’s book that a 2009 study had fabricated results By Jonathan WosenAug. 27, 2026 https://www.statnews.com/2026/08/27/marc-tessier-lavigne-responds-theo-baker-book-misconduct-stanford-genentech/

The unintended consequences of the Lindsay Clancy case How fear of liability could affect psychiatric care of mothers

https://www.statnews.com/2026/08/28/lindsay-clancy-postpartum-psychosis-reproductive-psychiatrists-liability/ By Renee Sorrentino and Susan Hatters FriedmanAug. 28, 2026 Sorrentino is a forensic psychiatrist in Boston. She is president-elect of the American Academy of Psychiatry and the Law. Friedman is a forensic and reproductive psychiatrist at Case Western Reserve University. She is past president of the American Academy of Psychiatry and the Law.

We quit the CDC last year. The problems we protested remain Here’s how Congress can protect the health of our country

https://www.statnews.com/2026/08/28/cdc-protest-resignations-one-year-later-houry-jernigan-daskalakis/ By Debra Houry, Daniel Jernigan, and Demetre DaskalakisAug. 28, 2026 Houry was the CDC’s chief medical officer and is now a senior medical adviser for the California Public Health Network Innovation Exchange. Jernigan, M.D., M.P.H., was director of the National Center for Emerging and Zoonotic Infectious Diseases, and is a contributing scholar at Johns Hopkins Bloomberg School of Public Health. Daskalakis, M.D., M.P.H., was director of the National Center for Immunization and Respiratory Diseases and is a consultant for Sanofi, AstraZeneca, and ViiV Healthcare.

The CMP Plot Thickens: Solicitor General Letter Casts FDA’s Tobacco Civil Money Penalty Scheme into Further Doubt August 27, 2026 By Peter G. Dickos & JP Ellison —

https://www.thefdalawblog.com/2026/08/the-cmp-plot-thickens-solicitor-general-letter-casts-fdas-tobacco-civil-money-penalty-scheme-into-further-doubt/?utm_source=rss&utm_medium=rss&utm_campaign=the-cmp-plot-thickens-solicitor-general-letter-casts-fdas-tobacco-civil-money-penalty-scheme-into-further-doubt For the first time, the Department of Justice has backed off its prior vigorous defense of FDA’s tobacco product administrative Civil Money Penalty (CMP) scheme as constitutional under the 7th Amendment and Jarkesy. Earlier this week, the Solicitor General sent a letter to Congress saying that it will not seek cert to the Supreme Court from the 5th Circuit’s adverse Texas Tobacco Barn decision finding the CMP there (for sales of unauthorized e-cigarettes) unconstitutional. The big part is the why: because “the Fifth Circuit correctly rejected certain arguments emphasized by the government in this case,” namely, that “interstate commerce” and “public health” were sufficient justifications to overcome/exceptions around the 7th Amendment jury trial right recognized in Jarkesy.

Who’s getting vaccinated? Scientific American ranks states by kindergarten vaccination rates Scientific American | August 28, 2026

https://geneticliteracyproject.org/2026/08/28/whos-getting-vaccinated-scientific-american-ranks-states-by-kindergarten-vaccination-rates/ America’s kindergartners are heading back to school less vaccinated than ever. New CDC data analyzed by Scientific American’s Jackie Flynn Mogensen and Sanidhya Sharma show kindergarten MMR vaccination fell to 92.4 percent this year, down from about 95 percent a decade ago, while nonmedical exemptions have roughly doubled, to 4 percent. Measles, once eliminated in the U.S., has logged over 2,500 cases this year, the most since 2000.

Viewpoint: Rebranding questionable ‘anti-aging’ claims as ‘longevity’ treatments is a fashionable new online wellness con Cheek Media | August 28, 2026

https://geneticliteracyproject.org/2026/08/28/viewpoint-rebranding-questionable-anti-aging-claims-as-longevity-treatments-is-a-fashionable-new-online-wellness-con/ The global wellness industry has swapped “anti-aging” for “longevity” — same unproven promises, shinier vocabulary — as Cheek Media’s Varsha Yajman reports in a recent investigation into the sector’s marketing tactics. The industry, valued at $6.8 trillion and projected to hit $9.8 trillion by 2029, increasingly relies on influencers rather than clinicians to sell its products, often to people who can least afford to be misled

Viewpoint: No, regenerative agriculture—whatever that means—is no better for the planet or your health than conventional farming that uses pesticides judiciously Cameron English | Orange County Register | August 28, 2026

https://geneticliteracyproject.org/2026/08/28/viewpoint-no-regenerative-agriculture-whatever-that-means-is-no-better-for-the-planet-or-your-health-than-conventional-farming-that-uses-pesticides-judiciously/ Americans have been subjected to a decades-long misinformation campaign about agriculture. Instead of the truth—conventional farmers grow ever-increasing amounts of food with relatively fewer pesticides—the public is told that regenerative agriculture is a safer path to sustainable nutrition, as HHS Secretary Robert F. Kennedy Jr. recently declared on X.

Viewpoint: Will Trump’s politicization of science undermine U.S. Nobel-level research? Lisa Song | August 27, 2026

https://geneticliteracyproject.org/2026/08/27/viewpoint-will-trumps-politicization-of-science-undermine-u-s-nobel-level-research/ For decades, physicists wrestled with a fundamental mystery of the universe. They wanted to know why certain particles — like the protons in atoms — have mass, while particles of light do not. Whatever the reason was, it was crucial to understanding the origins of planets, galaxies and life itself.

Viewpoint: Assessing and dissecting digital disinformation Anna Stone | August 28, 2026

https://geneticliteracyproject.org/2026/08/28/viewpoint-assessing-and-dissecting-digital-disinformation/ Recent reports have highlighted AI-generated “doctors” spreading dubious health advice to millions of social media users. Fabricated wellness trends can travel just as quickly. A supposed “pink jelly” weight-loss treatment, for example, reportedly fooled at least one celebrity.

“Am I a candidate for magic mushrooms?” A mystery shopper study of Oregon psilocybin service centers Danielle R Adams, PhD LMSW , Morgan Hartman, BA , Lisa Gong, BA , Suraj Shankar, MD , Ruth Ling, MD , Jacob T Steinle, MD , Joshua S Siegel, MD PhD , Ginger E Nicol, MD , Richard A Grucza, PhD , Jacob T Borodovsky, PhD

https://academic.oup.com/healthaffairsscholar/advance-article/doi/10.1093/haschl/qxag231/8771610?rss=1&login=false

FDA Drug Quality Assurance Inspections: Frequency, Outcomes, and Time to Reinspection, 2008–2025 Yunxiang Sun , Jeromie Ballreich , Joy Acha , Riya Modi , Mohammad Ali Alamdar Yazdi , Maqbool Dada , Tinglong Dai , Gerard Anderson , Mariana P Socal

https://academic.oup.com/healthaffairsscholar/advance-article/doi/10.1093/haschl/qxag229/8771609?rss=1&login=false

Primary Care, Weather, and the Missed Opportunity for Savings Maranna Yoder, PhD , Nilesh Shinde, PhD , Guangqing Chi, PhD , Seth Freedman, PhD , Kosali Simon, PhD , Sonia Angell, MD, MPH

https://academic.oup.com/healthaffairsscholar/advance-article/doi/10.1093/haschl/qxag225/8771608?rss=1&login=false

Primary Care Physician Characteristics and Potentially Inappropriate Medications in Older Adults Yuki Tatsuno, MD, MPH , Catherine A Sarkisian, MD, MSHS , John N Mafi, MD, MPH , Kei Kitajima, MEng , Daichi Sato, PhD , Yusuke Tsugawa, MD, PhD , Atsushi Miyawaki, MD, PhD

https://academic.oup.com/healthaffairsscholar/advance-article/doi/10.1093/haschl/qxag227/8772261?rss=1&login=false

History of drug pricing reform in the United States: From policy foundations to latest reforms Sujith Ramachandran, PhD , Arman Arabshomali, Pharm.D , John Coster, PhD

https://academic.oup.com/healthaffairsscholar/advance-article/doi/10.1093/haschl/qxag216/8772259?rss=1&login=false

Growing Up In An Aging America Jennifer L. Wolff August 28, 2026

https://www.healthaffairs.org/content/forefront/growing-up-aging-america?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz-_C1eihcQG2hX-9rgw42a1cpLwT6QdC1hAaId9d7NJ7To_2JIqX42d1_9vZ2mKhWO5Omn3LIdUIYZ6aDnh-Bx0qS5ibQA&_hsmi=435825747&utm_source=hasu In a new book review, Jennifer L. Wolff considers Aging Out: An Exploration of Caregiving, Community, and How Americans Grow Old by Lucy Schiller

The Fragmentation Tax On Medicare’s Prevention Push Farah Farahati August 24, 2026

https://www.healthaffairs.org/content/forefront/fragmentation-tax-medicare-s-prevention-push?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz--t330uHD9ilAAojsCvIdYx9hRhVdzEHxO7XbHtUZeyP0fsXCqqO-Gr3URiI4x4V-sarIlSRBsBRhTWGz_hBaZ3yHQKPw&_hsmi=435825747&utm_source=hasu The evidence from chronic kidney disease and Medicaid supportive housing suggests that new quality measures and payment pathways will underperform unless they also solve the fragmentation problem underneath them.

How The Current Ebola Outbreak Might Reshape American Foreign Aid Norma Ojehomon,Megan Schmidt-Sane,Constance Iradukunda,andMargaret Winchester August 26, 2026

https://www.healthaffairs.org/content/forefront/current-ebola-outbreak-might-reshape-american-foreign-aid?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz-8_ESIEKgMepG2KXoIhzS8W2LxHvkD15qKJvT1JoYnNlXx-1fOmjgAU5Bm0XCjSj4GMosHiq6yX2iKdvuwO2XAXa7Mqjw&_hsmi=435825747&utm_source=hasu Emergency funding is necessary, but a system dependent largely on episodic, reactive funding is ill-suited to moments of crisis or building long-term preparedness.

The Business of Autism: Private Equity, Medicaid & the Cost of Care Jeff ByersandDaniel R. Arnold August 28, 2026

https://www.healthaffairs.org/do/10.1377/hp20260827.806800/full/?utm_campaign=podcast&utm_medium=email&_hsenc=p2ANqtz--l0lIBA0eiUdE-xwVIOYDLBNrJMXItdpXQviZtcXCLpiJKpQLdEe_8u98OSlaFfbSGWmVNIePlFVWSSZy1of87j7O4oA&_hsmi=435825747&utm_content=hatw&utm_source=hasu Dan Arnold discusses the growth of Medicaid-funded autism treatment, the influence of private equity, and the challenge of managing costs while preserving access to care.

Hospital-Owned Medicare Advantage Plans: A Look at Pricing Patterns Grace MacklebyandRob Lott August 25, 2026

https://www.healthaffairs.org/do/10.1377/hp20260820.421251/full/?utm_campaign=podcast&utm_medium=email&_hsenc=p2ANqtz--4RNp66R4qgN4vSrdSu352mgPXBlr9TBw7GY1K3ztia8t5tlkLcQysPNJpFPNnJU8mcDsbclb0abdZ4cHhiONYRRrAyA&_hsmi=435825747&utm_content=ahp&utm_source=hasu Grace Mackleby discusses what hospital price transparency data reveals about Medicare Advantage "payviders," competition, and the real impact of vertical integration on healthcare costs.

Early Detection as a Biological Imperative: Expanding Equitable Access to Cancer Screening A Physical Laws Framework Analysis

Early Detection as a Biological Imperative: Expanding Equitable Access to Cancer Screening A Physical Laws Framework Analysis Gary A. Puckrein, PhD | President and Chief Executive Officer of the National Minority Quality Forum; Sam Asgarian, MD MBA | Vice President of Clinical Development, Guardant Health August 24, 2026 https://www.healthaffairs.org/sponsored-content/national-minority-quality-forum/early-detection-as-a-biological-imperative?utm_campaign=51133525-Health%20Affairs%20Sunday%20Update&utm_medium=email&_hsenc=p2ANqtz--OQQObFMm2Xw7ZZcHhVL5wJ5wZzANzsZDXZcOQFZi3M4kXZ2zdIZgCFE39X4APsXKOHV-GVR8YQ3C1ZLq_eLbf9lyZaA&_hsmi=435825747&utm_content=435825747&utm_source=hs_email Publisher's note: This material was paid for by National Minority Quality Forum and provided by National Minority Quality Forum. The views expressed by the author are their own. This material is not part of Health Affairs Forefront; it has not been subject to editorial review or revision by Health Affairs or Health Affairs Forefront except to avoid offensive, dangerous, or deceptive content and to conform with Health Affairs style conventions.

What Can You Say When You Can’t Say Everything? Authors: Lori Dorfman dorfman@bmsg.org, Liana B. Winett, Katherine Schaff, and Pamela Mejia

https://www.healthaffairs.org/doi/10.1377/hlthaff.2026.00921 Today’s decisions about what and how to communicate about population health occur amid very real fears and expectations of harsh reprisal that have had far-reaching impacts, both for people’s health and for the health professions. It is in this context that health researchers must share their findings with the public and policy makers, prevent confusion, and avoid harming groups already facing systemic barriers to health. In every communication context—from research papers to quotes on the nightly news—people must make thoughtful choices about what to say. Communication, therefore, is always an act of selection that requires both a clear purpose and a visible connection to the broader contexts for public health measures. With planning, skill, resources, and adherence to best practices for health communication, even difficult or easily misinterpreted information can be communicated clearly and accessibly while also maintaining accuracy. To build trust and be understood by the public and policy makers, public health researchers and practitioners must clearly, directly, contextually, and descriptively speak to the challenges affecting population health.

Artificial Intelligence and Health Care: What’s Next Paige Nong,Jonathan D. Ketcham,Halle Tecco,andMichael S. Gerber September 16, 2026, 11:00 AM

https://www.healthaffairs.org/do/10.1377/he20260819.334088/full/ What's the next wave of considerations the health care field should weigh regarding the use and impact of artificial intelligence? Halle Tecco, Paige Nong, and Jonathan Ketcham examine AI's greatest potential in health care, and where it can see the best ROI.

Reframing Clinical Accountability In Postacute Care Vania LeungandLauren J. Gleason August 28, 2026

https://www.healthaffairs.org/content/forefront/reframing-clinical-accountability-postacute-care If skilled nursing facilities are now a critical part of our health care continuum, then we must build the clinical oversight, medication safety infrastructure, and accountability mechanisms to match the dignity of the patients we serve.

To Omit Or Not To Omit? Why Transparency And Humility Are Compatible With Health Services And Public Health Leadership Author: Brian G. Southwell

https://www.healthaffairs.org/doi/10.1377/hlthaff.2026.00806 Professionals who oversee and implement communication efforts related to health services and public health face many challenges and sometimes may be tempted to omit information for a variety of reasons. Three important considerations undermine the case for adopting omission as a regular practice to pursue without caution. Wholesale omission is relatively difficult to correct after the fact; is often unnecessary, given the existence of established conventions to indicate missing information instead of withholding it; and misses opportunities to build trust by acknowledging nuance and uncertainty. We should avoid steering people toward what we think are the optimal perceptions for them to have if those perceptions are not based on accurate comprehension, even if we have legitimate or moral reasons in mind. We also should caution against message simplification without thoughtful justification. Communication benefits from humility: awareness of one’s own limits, openness to learning and change, and respect for others’ needs.

Health Services Professionals Endorse Omitting Some Research Information Under Limited Circumstances: Survey Authors: Alan S. Gerber, Mackenzie Lockhart, Eric M. Patashnik, and Harold A. Pollack

https://www.healthaffairs.org/doi/10.1377/hlthaff.2025.01440 In an era of polarization, misinformation, and declining public trust in experts, effective public communication about health research is essential for disseminating evidence and maintaining the credibility of the research enterprise. Yet when communicating research findings to general audiences, experts face dilemmas about whether to omit information to avoid public confusion, to prevent the stigmatization of marginalized constituencies, or to keep information from being weaponized against vulnerable groups. Drawing on a national survey of health services professionals conducted in April and May 2025, we found that respondents generally rejected omissions serving self-protective or politically strategic ends but accepted omissions aimed at preventing public confusion or harm to marginalized groups. There is meaningful variation in support for these justifications by ideology, education, and workplace. In weighted regressions, conservatives, PhD holders, and those working outside academia in government or other nonuniversity settings were less likely to endorse omissions as justified compared with liberals and moderates, non-PhDs, and university-based researchers. These findings reveal both common ground and meaningful division in how professionals view transparency, underscoring the need for research on actual communication behavior and guidance to help experts navigate these dilemmas.

Why Are Wealthy Americans Spending So Much More on Healthcare? Rob LottandBetsy Q. Cliff August 4, 2026

https://www.healthaffairs.org/do/10.1377/hp20260804.536834/full/?utm_campaign=podcast&utm_medium=email&_hsenc=p2ANqtz-9_sB0qKWlJVz4sY5tJp3CPgAQJLNn0h1uOBmMp5nKr5m_HhObwVCV-i8chtR8TSNrlqqBPaTURFIoSRolLcPIHxGa2_g&_hsmi=435825762&utm_content=ahp&utm_source=well%20read Health Affairs Publishing’s Rob Lott speaks to Betsy Cliff from the University of Chicago about her paper in the July 2026 issue of Health Affairs exploring trends in US healthcare spending by income.

AI and the Future of Patient Empowerment Jeff ByersandDavid Betts August 14, 2026

https://www.healthaffairs.org/do/10.1377/hp20260813.667154/full/?utm_campaign=podcast&utm_medium=email&_hsenc=p2ANqtz-9ucSfWGwnp-eXgXRTQ0VpNYDEAlewSRhLr-JkcjCx42cPfDY3L-hjjrT-yk403E78xc6xNJfHifnNYO0wu08vRyBe-FQ&_hsmi=435825762&utm_content=hatw&utm_source=well%20read How can AI help people preserve their voice and independence? David Betts shares how his experience with ALS led to the development of Talk To Me Goose and discusses the future of patient-centered innovation.

Housing First And Health: What The Evidence Says Leah Robinson,Kyle Moon,Sabriya L. Linton,andCraig Evan Pollack August 13, 2026

https://www.healthaffairs.org/content/briefs/housing-first-and-health-evidence?utm_campaign=health%20policy%20brief&utm_medium=email&_hsenc=p2ANqtz-9Swh3YY8rY8ltNPTphlxcTVu_oIbi-19z93Spqqw_h9WTEkhcmRS5crRfAs-CERHynMGgipEpGt66WzaW-0x9-wxkD6A&_hsmi=435825762&utm_source=well%20read Housing First has a strong and extensive evidence base demonstrating that it improves housing stability. Findings on health outcomes and costs are mixed, although it is not clear whether this reflects a true absence of health effects or challenges with research and implementation.

A National Strategy To End The Health Care Workforce Pipeline Crisis Amit JainandDiane Santa Maria August 12, 2026

https://www.healthaffairs.org/content/forefront/national-strategy-end-health-care-workforce-pipeline-crisis?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz-_wzy0_-N84eYlALDcdfNTYcl5XulJXRtsNgu0lsfT-LvoFoIAtrhgVJbZCji-EnnruOxzZkn6Rfi3oKga7IOsExyitfw&_hsmi=435825762&utm_source=well%20read Addressing the physician and nurse shortages will require both upstream interventions that build a shared health career pipeline and downstream investments that expand the distinct training capacities each profession requires. The authors outline a proposed national strategy to address workforce shortages across the health care system.

Spending On IDR Process Pushes No Surprises Act Costs To More Than $22.4 Billion Over Just Four Years Jack HoadleyandKennah Watts August 26, 2026

The independent dispute resolution process within the No Surprises Act has contributed an estimated $22.4 billion in total costs. These costs are primarily driven by a high volume of disputes and dispute awards that far exceed expected in-network rates. https://www.healthaffairs.org/content/forefront/spending-idr-process-pushes-no-surprises-act-costs-more-than-22-4-billion-over-just?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz--OwEmMwLsbREFAztrdKoN0NCKaSe7Ce6aThyEHS5oU-4_Fg0hQeuFIV0ZumSS_Hnw44745kqaQ4Rz1JI4j_8yv1j-0kw&_hsmi=435825762&utm_source=well%20read The article analyzes how the No Surprises Act’s independent dispute resolution (IDR) process has affected health care spending, estimating more than $22.4 billion in costs since its implementation.

Long-Awaited No Surprises Act Rule Finalized Lindsey Murtagh,Kennah Watts,Talia Egnal,andJack Hoadley August 12, 2026

The final rule should promote the identification of disputes either not subject to the NSA or ineligible for IDR. It does not address concerns that have arisen since the rule was first proposed, such as high provider win rates and award levels. https://www.healthaffairs.org/content/forefront/long-awaited-no-surprises-act-rule-finalized-1786106891322?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz-85WAhxs62JLEjk2lGu-ltzm5VUHgkmZEyc0b-W3KIaHMH5ssm_5xDbReyR0BWYFuI-jFJLg_wEGXR-tFj4_kmU3oQYcg&_hsmi=435825762&utm_source=well%20read This article examines the newly finalized No Surprises Act rule, highlighting how changes to the federal dispute resolution process aim to reduce administrative burdens, improve transparency, and streamline payment disputes between insurers and providers.

The Fair Pay, Fair Play TPA: A Proposal To Disrupt The Market For Health Plan Administration Christine H. Monahan,Kennah Watts,Karen Handorf,andKevin W. Lucia August 7, 2026

https://www.healthaffairs.org/content/forefront/fair-pay-fair-play-tpa-proposal-disrupt-market-health-plan-administration?utm_campaign=forefront&utm_medium=email&_hsenc=p2ANqtz-9oQlT-SF5Wf-TWa2UfcNbPDVIHnSvXz35Hp9-KVA9tLYszNhL5iEM1cowCJvzP5iBNLf88qJ2LlLSA2-iyhWW5B6KgPQ&_hsmi=435825762&utm_source=well%20read Congress should give employers a more accountable and affordable option to administer their medical benefit plans. The authors explore a proposal for a new third-party administrator model aimed at changing how self-funded employer health plans are managed.

The Uneven Distribution Of Patient Portal Messages Across Patients And Physicians Authors: A Jay Holmgren a.holmgren@ucsf.edu, Nate C. Apathy, Ateev Mehrotra, and Michael E. Chernew

The Uneven Distribution Of Patient Portal Messages Across Patients And Physicians Authors: A Jay Holmgren a.holmgren@ucsf.edu, Nate C. Apathy, Ateev Mehrotra, and Michael E. Chernew https://www.healthaffairs.org/doi/10.1377/hlthaff.2025.01416?utm_campaign=august%202026%20issue&utm_medium=email&_hsenc=p2ANqtz--0rlO2Aud3qlVVydIalM8TVUiw_KSiy0hfQYSZ3GclrC5kgfEyrP5jVmrYsaAVs1UA4lJ5z46KyafcNvXcO-GIvQGzBw&_hsmi=435825762&utm_source=well%20read A large study found that patient portal message volume is concentrated among a small share of patients and physicians, with high message burdens linked to increased after-hours EHR work.

Profitability Of Infused Biologics For Hospitals And Physician Practices: Case Study Of Keytruda Authors: James C. Robinson james.robinson@berkeley.edu, Ari Kosorukov, Mark Thomson, and Christopher M. Whaley

https://www.healthaffairs.org/doi/10.1377/hlthaff.2026.00334?utm_campaign=august%202026%20issue&utm_medium=email&_hsenc=p2ANqtz-9JC9qxuXRh1tTg6riilesK8-tWuBwzmhMBfbEzlGBJxgQ3N_CwHaqrqQ4cDO2kZZHHP5aDOCrEHKP_8e-cKBR77ulkOg&_hsmi=435825762&utm_source=well%20read A new analysis found that private insurer spending on Keytruda has surged alongside use of the drug, with hospitals, particularly those participating in the 340B program, earning substantially higher reimbursement margins than community physician practices.

The Economics Of Orphan Blockbuster Drug Development Authors: Jennifer C. Chen, Chris Madsen, and Anna Kaltenboeck

https://www.healthaffairs.org/doi/10.1377/hlthaff.2026.00209?utm_campaign=august+2026+issue&utm_medium=email&_hsenc=p2ANqtz-91aAWstCIZ7A3csyG3MFWmZXW_w-71eBCHj5cqzVOnlvoxpJ8lmqbQ5clKCRgFXQg6B4QQfOdv9vkXtX7cNRrSiWfBxA&_hsmi=435825762&utm_source=well+read Researchers found that blockbuster orphan drugs generally recoup their clinical trial costs as or more quickly than other high-spending drugs, raising questions about whether exemptions and delays in Medicare drug price negotiations are necessary to incentivize orphan drug development.

FDA’s Drug Registration and Listing Workshop: Compliance, Regulatory, and Submission Updates Tuesday, September 29, 2026

https://www.fda.gov/media/193623/download?utm_medium=email&utm_source=govdelivery Join SBIA as FDA shares the latest updates on registration and listing submissions, including current validation rules, and walks through the evolving regulatory requirements and compliance framework that shape how industry engages with these processes. We'll also dive into compliance strategies for drug amount reporting requirements — a great opportunity to ask questions and hear directly from those working at the forefront of these issues. https://www.fda.gov/drugs/news-events-human-drugs/fdas-drug-registration-and-listing-workshop-compliance-regulatory-and-submission-updates-09292026?utm_medium=email&utm_source=govdelivery

With Midterms Looming, Journalists Consider Measles, Food Recalls, and Obamacare Aug. 29, 2026

https://kffhealthnews.org/on-air/on-air-august-29-2026-measles-vaccination-food-recalls-midterm-elections/

$50B Rural Health Transformation Program Needs More Transparency, Groups Say By Arielle Zionts Aug. 27, 2026

https://kffhealthnews.org/rural-health/rural-health-transformation-program-transparency-50-billion-dollars-state-tracking/

Advancing Generic Drug Development: Modernizing Bioequivalence Approaches for Topical & Transdermal Products September 10, 2026

https://www.fda.gov/drugs/news-events-human-drugs/advancing-generic-drug-development-modernizing-bioequivalence-approaches-topical-transdermal?utm_medium=email&utm_source=govdelivery Are you developing a topical or transdermal generic drug product? Join this half-day virtual workshop to hear FDA experts discuss current regulatory recommendations, emerging bioequivalence approaches, and research that is helping streamline generic drug development and review. Attendees can ask questions and learn from case examples showing how GDUFA-funded research has informed guidance revisions and ANDA assessments. The workshop will also address characterization-based approaches, modeling and simulation, in vitro permeation testing (IVPT) method development, and recommendations for topical and transdermal delivery systems. Topics Current recommendations, implementation challenges, and alternative bioequivalence approaches for topical products. Case examples showing how GDUFA-funded research has informed guidance revisions, reduced submission deficiencies, and supported ANDA assessments. How empirical and in silico research supports product-specific guidances and characterization-based bioequivalence approaches, including robust IVPT method development. Recommendations and implementation strategies for topical and transdermal delivery systems, including how to determine when in vivo studies such as sensitization studies are appropriate Audience Scientists, researchers, current and prospective generic drug applicants, regulatory affairs professionals, and others who work on or have an interest in the development of topical and transdermal generic drug products. https://events-na12.adobeconnect.com/content/connect/c1/1315899612/en/events/event/shared/5118822171/event_registration.html?_charset_=utf-8&sco-id=7126601038&utm_medium=email&utm_source=govdelivery

How Doctors Find Their People: Medscape Physician Friendships Report 2026 Tony Stasiek

https://www.medscape.com/p11/how-doctors-find-their-people-medscape-physician-friendships-2026a1000rsm?ecd=WNL_physrep_260829_MSCPEDIT_physicians-friendships_etid8640174&uac=148436CN&impID=8640174

Longer Looks: Interesting Reads You Might Have Missed ++

Longer Looks: Interesting Reads You Might Have Missed https://kffhealthnews.org/morning-briefing/friday-august-28-2026/ Viewpoints: Healthcare System Is Failing In Multiple Ways; Congress Can Protect The CDC — And America's Health https://kffhealthnews.org/morning-breakout/viewpoints-u-s-healthcare-system-is-failing-in-multiple-ways-congress-can-protect-the-cdc-and-americas-health/

RFK Jr. And CDC Sow Doubt About Measles-Related Deaths In Pennsylvania ++++

RFK Jr. And CDC Sow Doubt About Measles-Related Deaths In Pennsylvania Amid a swelling measles outbreak, the top public health officials are accusing Gov. Josh Shapiro, a Democrat, of withholding information about the cases and are questioning whether measles caused the deaths. The Pennsylvania Health Department disputes those claims. The Lancaster County coroner said a newborn, who had evidence of the virus in lung tissue, suffered a ruptured spleen. https://kffhealthnews.org/morning-breakout/measles-082826/ CDC Is 'Charting The Course For The Future' With New 'Voyager' Project The CDC's chief operating officer, Sean Slovenski, announced the project in an email late last week, MedPage Today reported. The initiative aims to focus on emergency public health responses and infectious diseases, as well as "immediate improvements" to "simplify processes, reduce administrative burden, and remove barriers to advancing mission-critical work." https://kffhealthnews.org/morning-breakout/administration-news-082826/ Canada Lures Top US Researchers With $362M In Promised Funding Health, advanced digital technologies, and the environment are among the priority fields set out by the Canadian government to receive funding for research projects, Bloomberg reported. After promising an accelerated immigration pathway for H-1B visa holders last year, Canada is poaching some 48 U.S. researchers from elite institutions such as Harvard University and MIT. https://kffhealthnews.org/morning-breakout/pharma-and-tech-082826/ California Will Fine Hospitals, Insurers That Don't Comply With Spending Targets The California Office of Health Care Affordability voted unanimously Wednesday to discipline those who overspend, Modern Healthcare reported. Additionally, those who repeatedly fail to file acceptable performance improvement plans, don't implement corrective action plans, or falsify information could also face fines. https://kffhealthnews.org/morning-briefing/friday-august-28-2026/

New Covid Shots Are Coming: Drugmakers Promise Swift Distribution, But Uptake Hurdles Remain +++

New Covid Shots Are Coming: Drugmakers Promise Swift Distribution, But Uptake Hurdles Remain People 65 and older qualify for the shots, as do people who have an increased risk of severe infection. Off-label vaccines could be available to others, but some states don't permit pharmacists to give shots that haven't been OK'd by the CDC. The Advisory Committee on Immunization Practices, still in legal limbo, has not made a recommendation about whether the shots should be covered by insurance. https://kffhealthnews.org/morning-breakout/covid-082826/ 21 Years After Katrina, New Orleans Hospital To Be Reborn As Medical Research Hub Tulane University has announced that it is spearheading a $500 million effort to convert the building that once housed Charity Hospital into a pioneering medical research facility, AP reported. It has been shut for over two decades after the devastation of Hurricane Katrina. https://kffhealthnews.org/morning-breakout/health-industry-082826/ Researchers Have Created A Molecular Map Of Autism In The Brain The research, released Thursday in the journal Science, is a map of the genetic mutations associated with autism and how they affect the brain. Scientists hope to use this map to develop more targeted therapies. https://kffhealthnews.org/morning-breakout/mental-health-082826/

Why Older Pedestrians Fare Worse in Car Crashes By Paula Span Aug. 28, 2026

https://kffhealthnews.org/aging/older-pedestrians-risk-deaths-new-old-age/ On an August morning two years ago, Meredith Melville was crossing Piedmont Avenue in Oakland, California, to meet a friend at a cafe. While in the crosswalk, she noticed a car some distance away.

Trump and Kennedy’s Health Industry Deals Haven’t Been Enforced and Are at Risk of Vanishing By Stephanie Armour Aug. 28, 2026

https://kffhealthnews.org/health-industry/trump-kennedy-food-dyes-price-deals-unenforced-vanishing/ In the thick of his competitive reelection race in Michigan, Republican Rep. Tom Barrett joined Health and Human Services Secretary Robert F. Kennedy Jr. at a sprawling 400-acre apple orchard, farm, and winery. They touted Trump administration efforts to improve the American diet, including the removal of some artificial dyes from processed foods.

High Fertility Costs Push Americans Abroad for IVF Treatment By LJ Dawson Aug. 28, 2026

High Fertility Costs Push Americans Abroad for IVF Treatment Despite President Donald Trump’s promises to make fertility treatment more affordable, the overall costs for one IVF cycle in the U.S. remain in the tens of thousands of dollars. So more Americans than ever are going to Europe to seek IVF treatment for a fraction of the cost. By LJ Dawson Aug. 28, 2026 https://kffhealthnews.org/health-care-costs/ivf-tourism-fertility-in-vitro-fertilization-high-costs-pregnancy-parenthood-greece/

Overview of President Trump’s Executive Actions Impacting LGBTQ+ Health Authors: Lindsey Dawson and Jennifer Kates Published: Aug 21, 2026

https://www.kff.org/lgbtq/overview-of-president-trumps-executive-actions-impacting-lgbtq-health/ This tracker examines Executive Actions taken by the Trump administration that have the potential to impact LGBTQ+ people’s health. It lists the action taken by date, provisions relevant to LGBTQ+ health, and describes potential impact, including litigation challenging these actions.

The Status of Abortion-related State Ballot Initiatives Since Dobbs Last updated on August 21, 2026

The Status of Abortion-related State Ballot Initiatives Since Dobbs Last updated on August 21, 2026 Since the Supreme Court’s Dobbs decision, overturning Roe v. Wade, voters in 17 states have weighed in on ballot measures regarding abortion– some more than once. In November 2026, voters in Idaho, Missouri, Nevada, and Virginia will weigh in on abortion measures that could change the legal status of abortion in their state. In addition, a measure in Colorado is in the process of collecting signatures. https://www.kff.org/womens-health-policy/the-status-of-abortion-related-state-ballot-initiatives-since-dobbs/

The Trump Administration’s Proposed $103,265 Fee for H-1B Visas Could Affect the Health Care Workforce Drishti Pillai Published: August 26, 2026

The Trump Administration’s Proposed $103,265 Fee for H-1B Visas Could Affect the Health Care Workforce Drishti Pillai Published: August 26, 2026 https://www.kff.org/quick-insights/the-trump-administrations-proposed-103265-fee-for-h-1b-visas-could-affect-the-health-care-workforce/ The proposed $103,265 fee could lead to reductions in U.S. health care workforce, increasing barriers to care….A decline in H-1B workers would disproportionately impact states that employ the largest shares of H-1B workers (NY, MA, CA, and PA), lower income and rural areas where H-1B health care workers often are employed, and smaller employers, who would face greater challenges paying the fee.

Availability of Rural Hospitals Providing Inpatient Maternity Care in Medicaid Authors: Rhiannon Euhus, Brittni Frederiksen, and Alice Burns Published: Aug 26, 2026

https://www.kff.org/medicaid/availability-of-rural-hospitals-providing-inpatient-maternity-care-in-medicaid/ Considering the existing challenges to hospital-based maternity care in rural areas and the potential for it to worsen, this data note analyzes the availability of hospitals providing inpatient maternity care in rural areas for Medicaid enrollees and illustrates how access to these services could be affected if additional rural hospitals were to close or eliminate those services.

State and Federal Reproductive Rights and Abortion Litigation Tracker Last updated on Aug 26, 2026

State and Federal Reproductive Rights and Abortion Litigation Tracker Last updated on Aug 26, 2026 The Supreme Court’s Dobbs ruling, overturning Roe v. Wade, returned the decision to restrict or protect abortion to states. In many states, abortion providers and advocates are challenging state abortion bans contending that the bans violate the state constitution or another state law. Additionally, new questions have arisen regarding the intersection of federal and state authority when it impacts access to abortion and contraception. https://www.kff.org/womens-health-policy/litigation-involving-reproductive-health-and-rights-in-the-federal-courts/

Medicaid Coverage for Women Authors: Ivette Gomez, Usha Ranji, Alina Salganicoff, and Brittni Frederiksen Published: Aug 26, 2026

https://www.kff.org/womens-health-policy/medicaid-coverage-for-women/ Medicaid, the nation’s health coverage program for people with low incomes, provides more than 39 million women across the nation with health and long-term care coverage. Women comprise the majority of the adult Medicaid population and the program offers coverage of a wide range of primary, preventive, specialty, and long-term care services that are important to women across their lifespans. Given the importance of the program for women and their families, changes to the program, such as the 2025 federal policy changes to Medicaid and the enactment of new work requirements for the Medicaid expansion population, will have significant implications for low-income women’s access to coverage and care. This data note presents key data points describing the current state of the Medicaid program as it affects women.

Global COVID-19 Tracker Published: Aug 27, 2026

https://www.kff.org/covid-19/global-covid-19-tracker/ This tracker provides data on global COVID-19 cases and deaths by country, region, and income-level. Additionally, the tracker reports current closure, economic, and health system policy responses to the COVID-19 pandemic globally. This tracker will be updated as new data are available.

Different State Regulatory Approaches Reflect Open Questions About AI Mental Health Tools Joel Luther , Hagere Yilma , and Irving Washington

https://www.kff.org/health-information-trust/different-state-regulatory-approaches-reflect-open-questions-about-ai-mental-health-tools/ States are taking different regulatory approaches to AI mental health tools in response to concerns about chatbots providing inaccurate or potentially dangerous advice. Laws and pending legislation in some states restrict AI from providing or advertising itself as therapy, while others focus on data protections, disclosures, and requirements for patient consent.

Examining LGBTQ+ Adults’ Experiences with Health Care Costs and Access Authors: Grace Sparks, Ashley Kirzinger, Shannon Schumacher, Lindsey Dawson, and Liz Hamel Published: Aug 27, 2026

https://www.kff.org/public-opinion/examining-lgbtq-adults-experiences-with-health-care-costs-and-access/?utm_campaign=KFF-Polling-Surveys&utm_medium=email&_hsenc=p2ANqtz-8qZ1Lt4thqGz0NALnQAVecqXFZV5EkDXqyC7O7nmxf9qqlEX8TCdpN05-7UYdwYwSXjWFtDb3UdvuXMhzLocp1yV2VBg&_hsmi=435454057&utm_content=435454057&utm_source=hs_email Poll: LGBTQ+ Adults Are More Likely Than Other Adults to Face Challenges Accessing and Affording Health Care New KFF polling highlights the significant challenges that LGBTQ+ adults face in accessing and affording health care compared to their non-LGBTQ+ peers. The poll finds LGBTQ+ adults are more likely than others to postpone or skip needed care (58% vs. 38%), forgo prescription medications due to cost (22% vs. 12%), and struggle to pay medical bills (30% vs. 21%). Among LGBTQ+ adults, cost-related challenges are especially high for trans adults, those who are young, those with low incomes, and those who lack health insurance. LGBTQ+ adults are also more likely than others to face challenges with getting their health care covered by their insurance. For example, four in ten insured LGBTQ+ adults under age 65 say their insurance company delayed or denied coverage in the past two years—compared to a quarter of non-LGBTQ+ adults (26%). This includes six in ten (61%) trans adults. This survey was conducted May 4-26, 2026, online and by telephone among a nationally representative sample of 25,873 U.S. adults in English and in Spanish, including 2,640 LGBTQ+ adults. The margin of sampling error is plus or minus 1 percentage point for the non-LGBTQ sample, 3 percentage points for LGBTQ+ adults. For results based on other subgroups, the margin of sampling error may be higher. Contact: Tammie Smith | 202-654-1410 | TammieS@kff.org

States Tighten Private Equity Healthcare Oversight as Deals Slow Steph Weber

https://www.medscape.com/viewarticle/states-tighten-private-equity-healthcare-oversight-deals-2026a1000tu1 Private equity healthcare deals fell 18.5% in the second quarter of 2026 from a year ago, while deals in two key segments — physician practice management companies and generalist and multispecialty providers — were on pace to finish at about half of their 2025 levels, according to a new industry report.

Medscape State of the Medical Profession Index Report 2026: A Broken System? Tony Stasiek

https://www.medscape.com/p11/medscape-state-medical-profession-index-report-2026-broken-2026a1000tf8 In recent Medscape Insights reports, we've learned that a fair number of physicians are anxious about the cost of care affecting their relationships with patients. They're burned out, depressed, or both. And they're wondering what's up with the next generation of docs.

Watch Out! A Coding and Billing Audit May Be Coming Your Way Leslie Kane, MA

https://www.medscape.com/viewarticle/watch-out-coding-and-billing-audit-may-be-coming-your-way-2026a1000u12 The Centers for Medicare & Medicaid Services (CMS) and private payers are on a hunt to retrieve potential overpayments to physicians, and their new focus has put many doctors on edge.

FDA reminds compounders not to use dietary supplement grade glutathione for injectables

https://www.fda.gov/drugs/human-drug-compounding/fda-reminds-compounders-not-use-dietary-supplement-grade-glutathione-injectables?utm_medium=email&utm_source=govdelivery FDA is aware of reports of at least 30 patients who experienced adverse events following the administration of intravenous (IV) glutathione alone or in combination with other ingredients. The glutathione was compounded by different compounding pharmacies, all of which obtained their glutathione (Lot #229536) from Medisca Inc., U.S. headquarters in Plattsburgh, N.Y. The glutathione was labeled as dietary supplement grade, which is not an appropriate ingredient to make injectable drugs.

INSIDER EVENT: Artificial Intelligence and Health Care: What’s Next - Artificial Intelligence and Health Care: What’s Next Paige Nong,Jonathan D. Ketcham,Halle Tecco,andMichael S. Gerber September 16, 2026, 11:00 AM

https://www.linkedin.com/pulse/insider-event-artificial-intelligence-health-care-whats-rfvye/ What's the next wave of considerations the health care field should weigh regarding the use and impact of artificial intelligence? Halle Tecco, MPH, MBA , Paige Nong , and Jonathan Ketcham examine AI's greatest potential in health care, and where it can see the best ROI. The artificial intelligence (AI) era in health care is here. Where might we see the biggest impacts, and where might policymakers and health system leaders see the biggest ROI? In this Insider-only event moderated by senior editor Michael Gerber, leaders in the venture capital and health economics space open up about their perspectives on AI, health care, and where the two are heading. Panelists included Halle Tecco, venture capitalist and author of Massively Better Healthcare, Jonathan Ketcham of Arizona State University, and Paige Nong of the University of Minnesota. Date: September 16, 2026 Time: 11:00am - 12:00pm ET https://www.healthaffairs.org/do/10.1377/he20260819.334088/full/?utm_medium=email&utm_source=linkedin+newsletter&utm_campaign=insidermarketing&utm_content=eventspecific

Recent birth vitamin K rejectionism soaring in Canada CTV News | August 26, 2026

https://geneticliteracyproject.org/2026/08/26/recent-birth-vitamin-k-rejectionism-soaring-in-canada/ Canadian doctors are raising alarms over a growing number of parents refusing the routine vitamin K shot for newborns, as CTV News’s Heather Wright reports. The trend, driven largely by online misinformation, has physicians bracing for a resurgence of a rare, dangerous bleeding disorder.

U.S. badly trails China in lowering barriers to biotech innovation The Hill | August 26, 2026

https://geneticliteracyproject.org/2026/08/26/u-s-badly-trails-china-in-lowering-barriers-to-biotech-innovation/ America’s lead in biotechnology is eroding, and one Florida company’s three-year wait for a routine government stamp shows why, as The Hill’s David Mansdoerfer writes. China already runs more clinical drug trials than the U.S., even as America’s regenerative medicine market alone is projected to hit $90 billion by 2030.

RFK Jr. faces Senate fire over lucrative ties to Scientology-linked law firm spearheading Gardasil lawsuits (which he profited from) The Hill | August 27, 2026

https://geneticliteracyproject.org/2026/08/27/rfk-jr-faces-senate-fire-over-lucrative-ties-to-scientology-linked-law-firm-spearheading-gardasil-lawsuits-which-he-profited-from/ Four Senate Democrats are pressing Robert F. Kennedy Jr. to explain his financial ties to Wisner Baum, the Scientology-linked law firm spearheading lawsuits claiming Merck’s Gardasil HPV vaccine causes injury, as Joseph Choi for The Hill reports. Sens. Elizabeth Warren (D-MA), Richard Blumenthal (D-CT), Angela Alsobrooks (D-MD) and Andy Kim (D-NJ) sent Kennedy 21 questions demanding answers by August 11, after Merck agreed in June to pay $50 million to settle more than 200 Gardasil suits.

Viewpoint: The ‘glyphosate-free oats’ claim is fearmongering: Every risk agency in the world has assessed it as safe, and it isn’t even sprayed on oat plants AGDAILY | August 27, 2026

https://geneticliteracyproject.org/2026/08/27/viewpoint-the-glyphosate-free-oats-claim-is-fearmongering-every-risk-agency-in-the-world-has-assessed-it-as-safe-and-it-isnt-even-sprayed-on-oat-plants/ Slap “glyphosate-free” on a bag of oats and watch it fly off the shelf, even though the herbicide is barely used on the crop, writes Michelle Miller, aka the Farm Babe, for AgDaily. A former oat grower herself, Miller says she never met anyone who sprayed glyphosate on oats in the US, where it isn’t even approved for that use.

The politics driving Trump’s medically baseless order to break up combination childhood vaccines Amanda Seitz, Stephanie Armour | August 26, 2026

https://geneticliteracyproject.org/2026/08/26/the-politics-driving-trumps-medically-baseless-order-to-break-up-combination-childhood-vaccines/ President Donald Trump has ordered a reduction in childhood vaccines — publicly faulting the shots for an increase in autism cases — even as the nation’s top health official, Robert F. Kennedy Jr., has failed to produce evidence linking vaccinations to the disorder.

Viewpoint: Kennedy moves to close Big Food’s GRAS loophole—but will politically-protected Prevagen and Big Supplement slip through another? Chuck Dinerstein | August 27, 2026

https://geneticliteracyproject.org/2026/08/27/viewpoint-kennedy-moves-to-close-big-foods-gras-loophole-but-will-politically-protected-prevagen-and-big-supplement-slip-through-another/ With great fanfare, Secretary Kennedy announced the closing of the GRAS (“Generally Recognized As Safe”) loophole. But separating the rhetoric from the regulatory substance leaves me with a quandary: does the “radical transparency” he announced mean a cup half empty or half full?

Viewpoints: Menopausal Women Turn To Social Media When Doctors Don't Listen; We Are Seeing The Results Of RFK Jr.'s Rhetoric

https://kffhealthnews.org/morning-breakout/viewpoints-menopausal-women-turn-to-social-media-when-doctors-dont-listen-we-are-seeing-the-result-of-rfk-jr-s-rhetoric/

Research Roundup: The Latest Science, Discoveries, And Breakthroughs

https://kffhealthnews.org/morning-breakout/research-roundup-the-latest-science-discoveries-and-breakthroughs-76/

Mississippi To Launch Government-Run Health Market In The Face Of High Premiums

Mississippi To Launch Government-Run Health Market In The Face Of High Premiums According to Modern Healthcare, the Mississippi Insurance Department is preparing to spend $20 million in state funds to launch the “Mississippi Option” next year. The portal for short-term plans, ineligible for federal subsidies, features scaled-back prescription drug coverage and could help thousands of middle-class residents who can’t afford the premiums for health insurance exchange policies. https://kffhealthnews.org/morning-breakout/state-watch-082726/

Nonprofit Sues AMA Over Billing Codes, Alleges Copyright Misuse

Nonprofit Sues AMA Over Billing Codes, Alleges Copyright Misuse Earlier this month PatientRightsAdvocate.org sued the American Medical Association in federal court, claiming that it "has no valid copyright" and "has no right to withhold [Current Procedural Terminology] from the public and charge hefty fees for access," MedPage Today reported. An AMA spokesperson said it will "vigorously defend the AMA's intellectual property rights to ensure the continued access physicians and patients rely on." https://kffhealthnews.org/morning-breakout/health-industry-082726/

FDA Nominee Draws Ire Of MAHA Activists Who Fear She'll Sidestep Their Interests

FDA Nominee Draws Ire Of MAHA Activists Who Fear She'll Sidestep Their Interests People in the Make America Healthy Again movement point to Heidi Overton's role in President Donald Trump's executive order to spur production of a pesticide as a red flag that should sink her confirmation, The Washington Post reported. The White House says that Overton played only a bit role at the end of the process and that she “pushed as many MAHA-minded edits as possible." https://kffhealthnews.org/morning-briefing/thursday-august-27-2026/

Teens Mixed On Whether Meta's Big Changes To Insta, Facebook Will Help Their Mental Health

Teens Mixed On Whether Meta's Big Changes To Insta, Facebook Will Help Their Mental Health In a landmark settlement, Meta said it would pay up to $18 billion and establish restrictions for teen users, including daily usage limits, blocks on nighttime use, and disabling “like” counts. However, some teens shrugged at the news, telling The New York Times, “If anything, it’s just going to make kids fake their age more.” https://kffhealthnews.org/morning-breakout/mental-health-082726/

RFK Jr. Pushes Parental Choice In Floridians' Vaccine Uptake, Adds 'People Should Get The Measles' Shot

RFK Jr. Pushes Parental Choice In Floridians' Vaccine Uptake, Adds 'People Should Get The Measles' Shot During a visit to Florida, Health and Human Services Secretary Robert F. Kennedy Jr. also spoke about two recent measles deaths, claiming Pennsylvania health officials are withholding information about the cases. The state's health department confirmed to ABC News that an infant was one of the measles-associated deaths. https://kffhealthnews.org/morning-breakout/for-chris-public-health-082726/

Pancreatic Cancer Drug Receives FDA Approval

Pancreatic Cancer Drug Receives FDA Approval The drug, daraxonrasib, was approved Wednesday and will be sold under the name Rasonque. In clinical trials, patients who were given the drug showed nearly double the average survival time compared with those treated with chemotherapy. https://kffhealthnews.org/morning-breakout/cancer-research-082726/

Hospital Prepayment Requirements Add New Wrinkles to Patients’ Financial Responsibility By Julie Appleby Aug. 12, 2026

https://kffhealthnews.org/health-care-costs/hospital-prepayment-requirements-upfront-patient-insurance-deductible/?utm_campaign=KHN%3A%20Colorado&utm_medium=email&_hsenc=p2ANqtz-_Thrv7E0Qqf1sKmr2FD6RQfHc8B4c8-hEA_r2zQnfjeDqNxHidb3m7brV2Bl8pp7c3c3H8hnjmf1Yu6Jx3sFqJnSFVzQ&_hsmi=434983839&utm_content=434983839&utm_source=hs_email By Julie Appleby Thomas Zordani flew from his home in Denver to Phoenix for a consultation with a Mayo Clinic neurosurgeon, hoping to find out what could be done to treat his debilitating headaches after worrisome brain scan findings. When making the appointment, Zordani said, he’d been told the clinic was in his insurer’s network. Upon arrival, Zordani was summoned to the clinic’s financial office and told he had to make a $5,000 preservice deposit, because Mayo had since determined it did not accept his insurance. He was automatically designated “self-pay,” even though his plan had out-of-network benefits. Not having that kind of cash on hand — and angry on principle — he refused. His appointment was canceled. “I was so livid,” Zordani said, recalling that day in early April 2024. He later learned that Mayo had sent a message to him in his insurance carrier’s patient portal shortly before his visit with an estimate of the cost: $565, not the larger amount it later demanded. Traditionally, patients usually receive bills for their share only after getting treatment. But what Zordani faced is becoming increasingly common — hospitals or other medical providers seeking prepayments.

Listen to the Latest ‘KFF Health News Minute’ Aug. 20, 2026

https://kffhealthnews.org/news/listen-kff-health-news-minute-2026/?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz--FzElMWPzRYSsPpJj2v0q-YWn7gHTRZZGF30ngGkM9tUM-ZdHaeOs6-0bESFHRO4QOHmJR5-wt6CdD7vxFJmGPL5u-cg&_hsmi=435555472&utm_content=435555472&utm_source=hs_email KFF Health News: Listen To The Latest ‘KFF Health News Minute’ Arielle Zionts reads the week’s news: Pediatricians try to persuade more parents to vaccinate their kids amid measles outbreaks. Plus, how hospital monopolies drive up costs for patients and insurers. (8/20)

KFF Health News: A Camp For Children With Brain Injuries Zips Ahead, Despite Federal Uncertainty

https://kffhealthnews.org/news/children-with-brain-injuries-summer-camp-uncertain-federal-funding/?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz-_173mGou7tGUuQFTwknheVf6C7uSMOxJefl_cXe5TU-xUH8BirK-BF7Wk_nI5aurPasUhUvSwnVtpuBxvBGlDI7JuU_A&_hsmi=435555472&utm_content=435555472&utm_source=hs_email KFF Health News: A Camp For Children With Brain Injuries Zips Ahead, Despite Federal Uncertainty In an open field, arrows whizzed through the humid June air and struck their targets. Campers and counselors cheered. It was archery hour at Camp Cranium. Operations director Drew Meyer watched, a few tears escaping from behind his dark sunglasses. “They will surprise you, like, flat out,” he said of the campers, who have all survived brain injuries. “They’ll come out here, and they’ll shoot for three hours and start hitting the target.” (McFarlane, 8/27)

$50B Rural Health Transformation Program Needs More Transparency, Groups Say By Arielle Zionts Aug. 27, 2026

https://kffhealthnews.org/rural-health/rural-health-transformation-program-transparency-50-billion-dollars-state-tracking/?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz-8xOCWjJ5h3LeDFAmjONf1msoJS7u2byfsu7ll4JSUcjTLoCb69RjVR95P9r2OjR9VCKxEU9KzbLcB9gD5wWRd32ogHXQ&_hsmi=435555472&utm_content=435555472&utm_source=hs_email KFF Health News: $50B Rural Health Transformation Program Needs More Transparency, Groups Say One year into its creation, a $50 billion federal program aimed at improving rural healthcare lacks transparency, which could make it difficult to protect against fraud, identify successful projects, and ensure the program delivers on its promise to transform the system. Transparency “is really important to help protect the integrity of the program, ensure funds are reaching the communities they’re meant to serve,” said Maya Sandalow, director of health policy for the Bipartisan Policy Center, a nonprofit think tank. (Zionts, 8/27)

A State Gave Sheriffs 20% of Its Opioid Settlement Cash. We Followed the Money. By Aneri Pattani Data visualizations by Lydia Zuraw and photos by Christiana Botic Aug. 27, 2026

https://kffhealthnews.org/public-health/louisiana-sheriffs-opioid-settlement-spending-addiction-law-enforcement/?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz-_v6Sskww15iedyx45-LpI-FTzupoylpQGcgkWDO_aRnI4os1GsICX0taaJXTcKHOnutjE6vHin-DD1Bl1u_PnnQde6vA&_hsmi=435555472&utm_content=435555472&utm_source=hs_email KFF Health News: A State Gave Sheriffs 20% Of Its Opioid Settlement Cash. We Followed The Money Every state is receiving opioid settlement payouts from companies accused of flooding the nation with prescription painkillers and fueling overdose deaths. But only one state is directing 20% of those payouts to sheriffs — the largest carve-out for law enforcement nationwide. In Louisiana, sheriffs are elected, do not serve at the pleasure of another local official, and have independent budgets. They’re also not required to proactively report to the public or another authority how they spend billions in opioid settlement cash. (Pattani, 8/27)

A Costly 180: The D.C. Circuit Flips FDA’s Forfeiture Playbook August 27, 2026 By Peter G. Dickos & Sara W. Koblitz & Kurt R. Karst —

https://www.thefdalawblog.com/2026/08/a-costly-180-the-d-c-circuit-flips-fdas-forfeiture-playbook/?utm_source=rss&utm_medium=rss&utm_campaign=a-costly-180-the-d-c-circuit-flips-fdas-forfeiture-playbook What a year for Hatch-Waxman litigation! With the Supreme Court’s decision in Amarin v. Hikma, it’s already been a big year for the Hatch-Waxman Amendments, but now we have another case from the D.C. Circuit that touches on an important aspect of generic drug incentives: 180-day exclusivity. More specifically, 180-day exclusivity forfeiture, a topic so complicated that FDA’s Guidance on 180-Day Exclusivity spends 12 of its 26 pages of Frequently Asked Questions explaining it.

Transforming Health Care for Veterans, Revolutionizing Health Care for All

Transforming Health Care for Veterans, Revolutionizing Health Care for All https://digital.va.gov/ehr-modernization/news/ VA is transitioning to a new Electronic Health Record (EHR) system — the software that stores health information and tracks all aspects of patient care. The Federal EHR connects VA medical facilities with the Department of War (DOW), the U.S. Coast Guard (USCG), National Oceanic and Atmospheric Administration (NOAA), and participating community care providers, allowing clinicians to easily access a Veteran’s full medical history in one location. The VA EHRM Integration Office manages deployment of the new system. https://digital.va.gov/ehr-modernization/?utm_campaign=VetResources&utm_id=26AUG2026&utm_medium=email&utm_source=govdelivery

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

https://clinicaltrials.gov/study/NCT05406583?utm_medium=email&utm_source=govdelivery FDA Approves Drug to Treat HIV Infection in Newborns The U.S. Food and Drug Administration (FDA) has approved Tivicay PD tablets for oral suspension (dolutegravir) to treat HIV infection in babies from birth up to four weeks weighing at least 2 kg, in combination with other antiretroviral agents. Tivicay and Tivicay PD were previously approved for adults and children older than four weeks. Condition HIV (human immunodeficiency virus) is a virus that attacks the body's immune system, increasing the chances of developing serious infections or cancer and without treatment can lead to AIDS (acquired immunodeficiency syndrome). There is no cure for HIV, but prevention and treatment options are available. Data Supporting Tivicay PD in Newborns Data from the IMPAACT 2023 study and pharmacokinetic modeling data supported the application. In this study (NCT05406583), 48 newborns exposed to HIV 1 and weighing at least 2 kg received Tivicay PD from birth for up to six weeks, in combination with standard-of-care antiretroviral medications to prevent mother-to-child HIV transmission. The newborns were followed for 16 weeks. Results showed the drug levels of Tivicay PD in newborns were similar to those associated with efficacy in adults. The drug’s safety profile in newborns was also similar to that observed in older pediatric and adult patients. Safety Information Patients should not receive Tivicay or Tivicay PD if they had previous allergic reactions to the drug, or if they are also receiving dofetilide. Serious allergic reactions have been reported. Patients should be monitored for liver damage. Immune resconstitution syndrome has been reported in patients treated with combination antiretroviral therapy. Taking Tivicay or Tivicay PD with certain other medications may cause the drug to stop working against HIV or lead to serious side effects. Patients or their caregivers should tell their healthcare provider about all medications they are taking before starting Tivicay or Tivicay PD. Tivicay tablets and Tivicay PD tablets for oral suspension are not substitutable on a milligram-per-milligram basis. Designations Tivicay PD received priority review for this population.

Turkish antitrust authorities probe Teva for allegedly gaming the patent system, disparaging rival drugs Country’s regulators have been increasingly active in cracking down on global drugmakers

https://www.statnews.com/pharmalot/2026/08/25/turkish-authorities-probe-teva-gaming-patent-system-disparaging-rivals/ By Ed SilvermanAug. 25, 2026 Pharmalot Columnist, Senior Writer

After a years-long slump, Massachusetts biopharma sector has come roaring back in 2026 The state’s workforce shrank by about 3,600 employees in 2025

https://www.statnews.com/2026/08/25/massachusetts-biotech-slump-then-turnaround/ By Jonathan Saltzman — Boston GlobeAug. 25, 2026

Pennsylvania reports first 2 measles deaths in the U.S. this year, both people unvaccinated The country is enduring its worst year for the infection since 1991

https://www.statnews.com/2026/08/25/two-measles-deaths-reported-pennsylvania-residents-not-vaccinated/ By Associated PressAug. 25, 2026

Sword Health to acquire Headspace, according to filing The deal is expected to be effective Sept. 14

https://www.statnews.com/2026/08/25/sword-health-to-acquire-headspace-per-regulatory-filing/ By Mario AguilarAug. 25, 2026 Health Tech Correspondent

Many post-Dobbs abortion fears have not come to pass. What does that mean for advocates? Arguments about abortion rights should be rooted in freedoms, not data

https://www.statnews.com/2026/08/26/dobbs-abortion-predictions-infant-mortality-data-freedom/ By David N. HackneyAug. 26, 2026 Hackney is professor of reproductive biology at Case Western Reserve University and division chief of maternal fetal medicine.

Newer shingles vaccine linked to lower heart disease risk, ‘natural experiment’ shows Already tied to lower dementia risk by the same researchers, Shingrix will be tested further for cardiovascular benefits

https://www.statnews.com/2026/08/26/shingles-vaccine-shingrix-reduces-heart-disease-dementia-risk-oxford-study/ By Elizabeth CooneyAug. 26, 2026 Cardiovascular Disease Reporter

When it comes to women’s health, money talks Market forces are driving the case to fund research and improve treatment By Elizabeth CooneyAug. 26, 2026

https://www.statnews.com/2026/08/26/womens-health-reverse-pitch-profit-driven-approach-endometriosis-osteoporosis/ The flip side of each new discovery about women’s health is a history of research neglect. Now, as federal funding becomes increasingly precarious, some advocates, academics, and executives are appealing to another incentive.

New treatments for common cardiovascular risk factor near the market, with billions at stake Unlike cholesterol, there is no approved therapy to lower levels of Lp(a)

https://www.statnews.com/2026/08/26/lp-a-drugs-novartis-amgen-lilly-potential-heart-disease-blockbuster/?utm_campaign=the_readout&utm_medium=email&_hsenc=p2ANqtz-_j4oc0kn055CeJne1-XYT4EKk-0YYxqdval9J2yCLQxPPgNsglbo2adBj-wS3Z_b_pG-Cbth2Areh__uFg4NniwsTHqA&_hsmi=435329184&utm_content=435329184&utm_source=hs_email By Andrew JosephAug. 26, 2026 Europe Correspondent

Top Ten Essentials for Preventing Hospital Controlled Substance Diversion August 26, 2026 By Larry K. Houck —

https://www.thefdalawblog.com/2026/08/top-ten-essentials-for-preventing-hospital-controlled-substance-diversion/?utm_source=rss&utm_medium=rss&utm_campaign=top-ten-essentials-for-preventing-hospital-controlled-substance-diversion Former late night comedy institution David Letterman introduced his long-running, ever popular, Top Ten List* on Late Night with David Letterman on September 18, 1985. Drug Enforcement Administration (“DEA”) registrants, primarily hospitals/healthcare systems and pharmacies, have resolved alleged recordkeeping, reporting and security violations of the Controlled Substances Act and DEA regulations over the years by agreeing to pay civil penalties. Internal employee diversion was an important factor in some of those settlements. High profile settlements have resulted in civil penalties in millions of dollars and burdensome remedial programs as cost of continued operations.

Viewpoints: New York's Medical Aid In Dying Policy Puts A Burden On The Patient; Extreme Heat Negatively Affects Student Health

https://kffhealthnews.org/morning-breakout/viewpoints-new-york-approves-maid-but-with-a-safeguard-extreme-heat-negatively-affects-student-health/

World's Largest Generic Drugmaker Faces Antitrust Investigation

World's Largest Generic Drugmaker Faces Antitrust Investigation Turkish antitrust authorities this month launched the probe into whether Teva Pharmaceuticals manipulated the patent system to squash competition, Stat reported. Teva has denied any wrongdoing and agreed to cooperate with investigators. https://kffhealthnews.org/morning-breakout/pharma-and-tech-082626/

Waterbury, Conn., Making It Easier For Healthcare Workers To Live Affordably Near Their Jobs

Waterbury, Conn., Making It Easier For Healthcare Workers To Live Affordably Near Their Jobs The city and the state's Department of Housing are teaming up to build 47 affordable housing units across the street from Saint Mary’s Hospital and a couple miles from Waterbury Hospital. Connecticut is also in early-stage talks with two other hospitals about opportunities for affordable housing development, The CT Mirror reported. https://kffhealthnews.org/morning-breakout/state-watch-082626/

Dolly Parton Leaves A Legacy Of Healthcare Philanthropy

Dolly Parton Leaves A Legacy Of Healthcare Philanthropy For the past two decades, the country music icon — who died Tuesday at age 80 — donated millions of dollars to numerous medical and scientific establishments. Her gifts helped fund the Moderna covid vaccine, a pediatric cancer center, a women's health center, and more. https://kffhealthnews.org/morning-breakout/dolly-parton-082626/

Gov. Shapiro Rips RFK Jr. Over Vaccine Messaging After 2 Pennsylvanians Die Of Measles

Gov. Shapiro Rips RFK Jr. Over Vaccine Messaging After 2 Pennsylvanians Die Of Measles "There’s real-life consequences to scaring people and not relying on actual doctors, actual medical professionals, to provide unbiased information," the governor said, noting that not one person confirmed to have measles in the current outbreak has been fully vaccinated. Almost 400 cases of measles have been confirmed in Pennsylvania, nearly half of them in Lancaster County. https://kffhealthnews.org/morning-breakout/outbreaks-and-health-threats-082626/

Trump Can't Restrict Federal Healthcare Funding For Those Not Meeting His Conditions, Court Rules

Trump Can't Restrict Federal Healthcare Funding For Those Not Meeting His Conditions, Court Rules Nothing in federal law “contemplates conditions based solely on a perception that the programs are inconsistent with the President’s views on hot-button issues,” read the ruling by the 9th U.S. Circuit Court of Appeals in San Francisco. The administration had sought to withhold grant funding from local entities whose policies didn't align with the government's. https://kffhealthnews.org/morning-breakout/administration-news-082626/

In Toss-Up House District, Voters Crave Leadership To Fix Broken Healthcare By Samantha Rangel, KVPR Aug. 26, 2026

https://kffhealthnews.org/elections/california-22nd-congressional-district-valadao-villegas-healthcare-affordability/ BAKERSFIELD, Calif. — Carlos A. grew up in a family on Medicaid, which made healthcare an afterthought since the public insurance is free for low-income enrollees. But when he received a raise two years ago, he found himself earning too much to qualify for the safety net program. And when he browsed Covered California plans, he found that marketplace prices were still too steep for his comfort.

Trump’s ICE Has Detained More People Than the Population of Atlanta Unlike prior administrations, in Trump’s second term, ICE is aggressively arresting people far from the border and detaining them longer.

https://www.themarshallproject.org/2026/08/25/immigrant-detention-trump-ice-thousands-length?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz-_1unM7CoPlsIDUrdA-xbcRwyM_wHgQUP2ziKDo9frmrNdTdJFg4WjIQkwvIsEeTskvrlKFJdyIZjDosk26NEgYHKHXGA&_hsmi=435310199&utm_content=435310199&utm_source=hs_email The Marshall Project: 600K People Put In Immigration Detention During Trump’s Second Term More than 45,000 people were detained by Immigration and Customs Enforcement last month, the highest number since Donald Trump retook office, according to data the Deportation Data Project released Monday. In total, since Trump’s inauguration last year, ICE has detained over 610,000 people — more than the population of Atlanta, Baltimore, Milwaukee or the entire state of Wyoming. (Schwartzapfel and Flagg, 8/25)

Trump can’t cut off funding to communities whose policies he opposes, court rules By Bob Egelko, Staff Writer Aug 25, 2026

https://www.sfchronicle.com/politics/article/trump-can-t-cut-funds-cities-policies-opposes-22403177.php?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz--awjog0-cRqllx6WwBfNSVBXHRnPzWiI4KlA4xU-una_-5bfmRiI-tM95eIw8ImCvT9oRgBDT4WSabi3bS9Z8-P8I2cA&_hsmi=435310199&utm_content=435310199&utm_source=hs_email San Francisco Chronicle: Trump Can't Cut Funds To Cities With Policies He Opposes, Court Rules The Trump administration has no legal authority to cut off billions of dollars in federal health care and housing funds to local governments, including San Francisco, Alameda, Santa Clara and Sonoma counties, unless they cooperate with his policies on immigration, abortion and “gender ideology,” a federal appeals court ruled Tuesday. While engaged in separate court battles to cut off funding for abortions and medical care for transgender youths, President Donald Trump has also sought to withhold aid to cities and counties that use any funds, including their own, for abortions or transgender care, an

Trump Puts Autistic Kids in the Spotlight and Cuts Agencies Built To Protect Them By Claire Sibonney Aug. 26, 2026

https://kffhealthnews.org/race-and-health/education-department-civil-rights-office-autism-diagnosis-support-discrimination/?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsenc=p2ANqtz-9-aonCx8NWtvm46ILP0QKMTdLR_h3koDKejy4JH4Xaerc7hUWlsY2EauVQ3iGR4EdSB9g8rDScyWb8nSwcG8b2Bejl9g&_hsmi=435310199&utm_content=435310199&utm_source=hs_email KFF Health News: Trump Puts Autistic Kids In The Spotlight And Cuts Agencies Built To Protect Them At Chain of Lakes Elementary School in Winter Haven, Florida, Josette Smith’s 9-year-old son, Ethan, gets to do what he loves most: crafts, math, and science. That is, when he isn’t being pulled out of class. Ethan has autism and attention-deficit/hyperactivity disorder. He was diagnosed with autism in kindergarten after displaying behavior that concerned his relatives: He paced, flapped his arms, and became consumed with highly specific interests, such as Martin Luther King Jr. and dachshunds. (Sibonney, 8/26)

Her Breast MRI Was Approved, But That Didn’t Mean Her Insurance Would Pay A woman in Washington state discovered that unlike mammograms, breast MRIs aren’t universally covered as zero-cost preventive care.

Her Breast MRI Was Approved, But That Didn’t Mean Her Insurance Would Pay A woman in Washington state discovered that unlike mammograms, breast MRIs aren’t universally covered as zero-cost preventive care. By Lauren Sausser Aug. 26, 2026 1. Her Breast MRI Was Approved, But That Didn’t Mean Her Insurance Would Pay Stephanie Halver’s doctor recommended she get a breast MRI, partly because of her family’s cancer history. Her insurer approved the scan, but unlike mammograms, breast MRIs aren’t universally covered as zero-cost preventive care. (Lauren Sausser, 8/26) https://kffhealthnews.org/health-care-costs/breast-cancer-mri-preventive-care-bill-of-the-month-august-2026/ KFF Health News: Her Breast MRI Was Approved, But That Didn’t Mean Her Insurance Would Pay Last year, Stephanie Halver’s primary care doctor consulted a risk assessment tool to calculate her chances of one day developing breast cancer. Halver, now 43, remembered the likelihood “popped up really high.” That’s partly because Halver’s mother and aunt have had breast cancer. Her age and dense breast tissue also put her at higher risk. (Sausser, 8/26)