domingo, 2 de agosto de 2020

Equity in Health: Consideration of Race and Ethnicity in Precision Medicine - PubMed

Equity in Health: Consideration of Race and Ethnicity in Precision Medicine - PubMed



Equity in Health: Consideration of Race and Ethnicity in Precision Medicine

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Free PMC article

Abstract

The causes for disparities in implementation of precision medicine are complex, due in part to differences in clinical care and a lack of engagement and recruitment of under-represented populations in studies. New tools and large genetic cohorts can change these circumstances and build access to personalized medicine for disadvantaged populations.
Keywords: genetic ancestry; genomics; health disparities; health equity; personalized medicine.

References

    1. Colby S.L., Ortman J.M. Population estimates and projections. United States Census Bureau; 2015. Projections of the size and composition of the US population: 2014 to 2060. (Current population reports).
    1. Mautz B.S. Temporal changes in genetic admixture are linked to heterozygosity and health diagnoses in humans. bioRXiv. 2019 doi: 10.1101/697581. Published online July 12, 2019 . - DOI
    1. Schaeffer K. FactTank: News in in Numbers. Pew Research Center; 2019. The most common age among whites in US is 58-more than double that of racial and ethnic minorities.
    1. Martin A.R. Clinical use of current polygenic risk scores may exacerbate health disparities. Nat. Genet. 2019;51:584–591. - PMC - PubMed
    1. Popejoy A.B., Fullerton S.M. Genomics is failing on diversity. Nature. 2016;538:161–164. - PMC - PubMed

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