Multiple sclerosis has distinct subtypes, study finds, pointing to different treatments Isabella Cueto By Isabella Cueto March 27, 2024

https://www.statnews.com/2024/03/27/multiple-sclerosis-subtypes-treatment/?utm_campaign=morning_rounds&utm_medium=email&_hsmi=300173672&_hsenc=p2ANqtz-89XwYlrfRhtks3bPQ2Wg7C5GimOxmGG-couIskB_fpmwe1Mj69SWvi_YPoPMnQl7XR7P7sMvk7Ut533zvvII1gt1qhGA&utm_content=300173672&utm_source=hs_email Study discerns different MS subtypes As chronic conditions go, multiple sclerosis is a difficult one to live with and to treat. Thought to be more common in women, it causes vision problems, fatigue, and weakness or spasms in the arms and legs, among many other symptoms. But the neurological condition doesn’t always look the same. That spurred a team of scientists across Germany to look for clues in its earliest stages. A new study published yesterday in Science Translational Medicine sheds light on three specific subgroups of the disease they found in 500 patients, corresponding with differences in immunological activation early in their disease and sustained over the study’s four years. This could suggest the disease arises through multiple immune system pathways, the researchers say. And because the groups responded differently to treatments over time, that might help inform their care and future drug development. STAT’s Isabella Cueto has more. https://www.science.org/doi/10.1126/scitranslmed.ade8560?utm_campaign=morning_rounds&utm_medium=email&_hsmi=300173672&_hsenc=p2ANqtz-_f6eYt02U37OV5dN0eI_c1ptVu_WK_9ot1dg8YK3Ah6dIy0BfU_nvVyxRee6cDX9lGtLI5CbjcMJX4in-35ozt1PoEWA&utm_content=300173672&utm_source=hs_email