Advancing Health Disparities Science Through Social Epigenomics Research

https://pubmed.ncbi.nlm.nih.gov/39073810/ Advancing health disparities science through social epigenomics research This thematic issue of JAMA Network Open highlights new findings from the grantees of the National Institutes of Health (NIH) Social Epigenomics Program. These findings, taken together, examine the associations of a variety of social, behavioral, and structural factors throughout the life course with epigenomic and other biological changes among populations experiencing health disparities. The studies link early-life exposures, structural inequities, and behavioral factors and interventions to epigenetic changes, and in some studies, later health outcomes. While there is still more work to be done to fully characterize the mechanistic pathways linking social exposures to epigenetic changes and health outcomes, the body of work presented in this special issue represents solid progress toward this goal. Author: Arielle S. Gillman*, Eliseo J. Pérez-Stable*, and Rina Das* Journal: JAMA Network Open, July 29