Seattle Sees Dramatic Decline In Syphilis Cases After DoxyPEP Rollout

Seattle Sees Dramatic Decline In Syphilis Cases After DoxyPEP Rollout Using public data from January 2017 to June 2025, researchers saw a 52% relative reduction in overall syphilis cases after the post-exposure prophylaxis was introduced in March 2023 compared with the pre-implementation period. The process involves taking a dose of the antibiotic doxycycline within 72 hours of unprotected sex and is recommended for men who have sex with men (MSM) and transgender women who have sex with men. https://kffhealthnews.org/morning-breakout/seattle-sees-dramatic-decline-in-syphilis-cases-after-doxypep-rollout/