Your questions on ‘real-world evidence,’ answered

Are data gathered outside a clinical trial actually reliable? How stodgy is the FDA? And when will algorithms replace placebos?

We locked STAT’s Matt Herper in a room for an hour and forced him to answer these and many more questions about the rise of so-called real-world evidence, a catch-all term for medical findings that don’t arrive through the golden gates of randomized clinical trials.

If you’re curious about regulatory dogma, the future of personalized medicine, and whether the idea of a synthetic control arm is more hype than reality, you can take a deep dive right here.