Systematic Review Now Available

Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults
(Systematic Review, released on March 28, 2019)

This systematic review assesses adverse events of antidepressants in the treatment of major depressive disorder in adults 65 years of age or older.

Opportunity to Comment on Draft Reports

We encourage the public to participate in the development of our research projects. Comments can be submitted for:

Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review
Available for comment until April 25, 2019

This systematic review evaluated the effectiveness and harms of pharmacologic and nonpharmacologic treatments for acute exacerbations of chronic obstructive pulmonary disease.

Treatment for Acute Pain: An Evidence Map
Available for comment until April 25, 2019

The purpose of this evidence map is to provide a high-level overview of the current guidelines and systematic reviews on pharmacologic and nonpharmacologic treatments for acute pain. We map the evidence for several acute pain conditions including postoperative pain, dental pain, neck pain, back pain, renal colic, acute migraine, and sickle cell crisis. Improved understanding of the interventions studied for each of these acute pain conditions will provide insight on which topics are ready for comprehensive comparative effectiveness review.

Opportunity to Comment on Draft Key Questions

We encourage the public to participate in the development of our research projects. Comments can be submitted for:

Integrating Palliative Care With Chronic Disease Management in Ambulatory Care
Available for comment until April 17, 2019

Management of Primary Headaches in Pregnancy
Available for comment until April 11, 2019

Opportunity to Submit Scientific Information

The Effective Health Care (EHC) Program is interested in receiving supplemental evidence and data (SEADs) for systematic reviews that are relevant to the questions in our evidence reports. To ensure that it has full access to relevant research, whether or not it is published, the EHC Program is interested in receiving SEADs containing detailed study-specific information. Opportunities to submit scientific information are available for:

Skin Substitutes for Treating Chronic Wounds
Available for submissions until April 29, 2019

About us: AHRQ’s Effective Health Care Program is committed to providing the best available evidence on the outcomes, benefits and harms, and appropriateness of drugs, devices, and health care services and by helping health care professionals, patients, policymakers, and health care systems make informed health care decisions. The program partners with research centers, academic institutions, health professional societies, consumer organizations, and other stakeholders to conduct research, evidence synthesis, evidence translation, dissemination, and implementation of research findings.

To learn more: https://www.effectivehealthcare.ahrq.gov