They went and CRISPR’d someone
In a first, scientists have used CRISPR to edit genes inside a person’s body, part of a landmark clinical trial for technology’s future as a medicine.
As the Associated Press reports, doctors at Oregon Health and Science University in Portland administered a single dose of EDIT-101, a CRISPR therapy invented by Editas Medicine, into a patient with a rare, inherited eye disease that causes blindness. The plan is to treat 18 patients total in a trial meant to determine first whether the treatment is safe and then if it can restore vision.
The future of that treatment, partnered with Allergan, is key to CRISPR’s potential as a therapy. The genome editing technology has already revolutionized research, and scientists have figured out how to create cell therapies by editing them outside the body, but a huge swath of diseases that might benefit from CRISPR would require in vivo editing. If EDIT-101 works, that will look a lot more possible.
Read more.
As the Associated Press reports, doctors at Oregon Health and Science University in Portland administered a single dose of EDIT-101, a CRISPR therapy invented by Editas Medicine, into a patient with a rare, inherited eye disease that causes blindness. The plan is to treat 18 patients total in a trial meant to determine first whether the treatment is safe and then if it can restore vision.
The future of that treatment, partnered with Allergan, is key to CRISPR’s potential as a therapy. The genome editing technology has already revolutionized research, and scientists have figured out how to create cell therapies by editing them outside the body, but a huge swath of diseases that might benefit from CRISPR would require in vivo editing. If EDIT-101 works, that will look a lot more possible.
Read more.
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