Household Water Lead and Hematologic Toxic Effects in Chronic Kidney Disease

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2818894?guestAccessKey=9dd9b616-a925-47e2-842c-f8818012b31a&utm_term=052824&utm_campaign=ftm_links&utm_medium=referral&_hsenc=p2ANqtz-9e32GfOu2APltlmmAc6LuBvPTIw7AFn4QC9p4a5gsnskoEA9_Fc9iF_L0m13NvmYq5GEad2t9dqLRqR_TIlNxAczGNzg&_hsmi=309132552&utm_content=tfl&utm_source=For_The_Media Even common levels of lead could be dangerous for kidney patients A first-of-its-kind study published yesterday in JAMA Internal Medicine analyzed how common household levels of lead contamination in the U.S. water supply may affect people with chronic kidney disease. Lead poisoning is common in the U.S., and people with chronic kidney disease are particularly vulnerable. So when patients receive dialysis, which helps filter the blood, their home water supply is typically tested for toxins to ensure safe treatment. The researchers found that, among more than 6,400 chronic kidney disease patients, 12% had measurable lead in their home drinking water. To quantify the impact of contamination, researchers measured exposure against the patients’ dosage level of an anemia treatment, a proxy for the toxic effect lead has on the blood. Of patients with measurable lead in their water, a higher category of lead contamination was linked with 15% higher risk of using the maximum dose of that treatment. The results indicate, the authors write, that that even common levels of lead could have negative health effects for vulnerable individuals.Even common levels of lead could be dangerous for kidney patients A first-of-its-kind study published yesterday in JAMA Internal Medicine analyzed how common household levels of lead contamination in the U.S. water supply may affect people with chronic kidney disease. Lead poisoning is common in the U.S., and people with chronic kidney disease are particularly vulnerable. So when patients receive dialysis, which helps filter the blood, their home water supply is typically tested for toxins to ensure safe treatment. The researchers found that, among more than 6,400 chronic kidney disease patients, 12% had measurable lead in their home drinking water. To quantify the impact of contamination, researchers measured exposure against the patients’ dosage level of an anemia treatment, a proxy for the toxic effect lead has on the blood. Of patients with measurable lead in their water, a higher category of lead contamination was linked with 15% higher risk of using the maximum dose of that treatment. The results indicate, the authors write, that that even common levels of lead could have negative health effects for vulnerable individuals. Half of US population exposed to adverse lead levels in early childhood https://www.pnas.org/doi/10.1073/pnas.2118631119?utm_campaign=morning_rounds&utm_medium=email&_hsenc=p2ANqtz-8U_xjixds7kc1yu_RCWfhs_dJgPEOA12gGPH4xvbBstlpFrqZbWqCzblR12e7Q3nrR34-ZGIiRla7jZib090mV287-IQ&_hsmi=309132552&utm_content=309132552&utm_source=hs_email