08/31/2018 12:00 AM EDT
This 78-page report details a project that conducted interviews regarding the methodology and data requirements for assessing vulnerability of certain populations to the health impacts associated with extreme heat in the U.S., and for developing vulnerability maps that characterize and locate vulnerable populations. The document is designed to inform state and local health departments, community planners, emergency preparedness professionals, and other stakeholders as they prepare maps that convey useful knowledge on exposure to extreme heat while helping to identify and implement effective adaptation strategies.
08/31/2018 12:00 AM EDT
This eight-page update of the European Centre for Disease Prevention and Control’s risk assessment on Middle East respiratory syndrome coronavirus (MERS-CoV) was triggered by the detection of a case imported into the European Union/European Economic Area (EU/EEA) from the Kingdom of Saudi Arabia (KSA). It reassesses the risk for EU/EEA residents, which in the healthcare setting remains low, provided appropriate infection control measures are implemented rapidly when seeing suspected cases.
08/31/2018 12:00 AM EDT
This web page describes how statisticians at the Food and Drug Administration are designing trials with adaptive features to make clinical evaluation of new drug treatments more efficient and informative. It discusses how they worked in collaboration with the National Institutes of Health, several academic centers, and investigators in Liberia, Sierra Leone, and Guinea to design a trial to evaluate treatments for the Ebola virus during the 2014-2015 outbreak, and how they are promoting and developing other innovative trials that meet the challenges of precision medicine.
08/31/2018 12:00 AM EDT
This 10-page letter describes the Emergency Use Authorization (EUA) for emergency use of Pathogen-Reduced Leukocyte-Depleted Freeze Dried Plasma for U.S. military forces. It can be used for the treatment of hemorrhage or coagulopathy during an emergency involving agents of military combat (e.g., firearms, projectiles, and explosive devices) when plasma is not available for use or when the use of plasma is not practical.
08/31/2018 12:00 AM EDT
This 56-page report describes the procedures to develop Provisional Advisory Levels (PALs) for hazardous chemicals by identifying health effects that increase in severity with increasing exposure, and by organizing them according to exposure durations common during and following an emergency chemical release. It distinguishes the types of chemical risk information necessary to support emergency response decisions, and emphasizes the importance of having advisory exposure guidance values that are developed specifically for emergency response situations
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