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An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children: Cross-Cultural Differenc... - PubMed - NCBI

2017 Mar - Apr;5(2):363-368.e2. doi: 10.1016/j.jaip.2016.09.049. Epub 2016 Dec 22.

An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children: Cross-Cultural Differences in Age and Impact in the United States and Europe.

DunnGalvin A1, Koman E2, Raver E2, Frome H2, Adams M2, Keena A3, Hourihane JO4, Gallagher PL5, Flokstra-de Blok B6, Dubois A7, Pyrz K3, Bindslev-Jensen C8, Stensgaard A8, Boyle R9, Vickers B9, Smith J9, Thisanayagam U9, Greenhawt M10.

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Correction. [J Allergy Clin Immunol Pract. 2017]

Abstract

BACKGROUND:

It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.

OBJECTIVES:

The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.

METHODS:

In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.

RESULTS:

The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.

CONCLUSIONS:

The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings.