To address prescription opioid abuse, U.S. Surgeon General Vivek H. Murthy, M.D., M.B.A, launched the “Turn the Tide” initiativeand sent a letter to more than 2.3 million health care practitioners and public health leaders asking for their help in addressing opioid addiction. To augment efforts to reduce opioid abuse, AHRQ recently announced a series of grants to research how to support rural primary care practices in delivering medication-assisted treatment (MAT) for people addicted to opioids, as well as how to overcome barriers to MAT in rural communities. AHRQ is investing approximately $9 million over three years to help rural primary care practices provide access to treatment to more than 20,000 people with opioid addiction. AHRQ’s initiative supports practices through the use of in-person practice facilitation as well as technologies, including patient-controlled smart phone apps, remote training and use of Project ECHO, a program that links primary care clinicians in rural communities with specialist care teams at university medical centers. Visit AHRQ’s National Center for Excellence in Primary Care Research to learn more.