Two Treatments for Major Depressive Disorder Are Equally Effective When Used in Community Mental Health Settings
An AHRQ-funded study found that two mental health treatments --short-term dynamic psychotherapy and cognitive therapy -- were equally effective in decreasing symptoms of major depressive disorder among patients receiving services in a community mental health center. The study was based on about 240 patients with major depressive disorder who received 16 outpatient sessions of either intervention between 2010 and 2014. Short-term dynamic psychotherapy aims to help patients understand reasons for their relationship conflicts, while cognitive therapy helps patients identify thoughts and behavior that led to their depression. This randomized clinical trial was designed to determine whether short-term dynamic therapy, a widely used treatment that lacks a robust evidence base, is not inferior to cognitive therapy, a treatment with well-documented effectiveness. The treatments were found to be equivalent based on clinical evaluators’ blind ratings of participants’ symptoms. The study, “Comparative Effectiveness of Cognitive Therapy and Dynamic Psychotherapy for Major Depressive Disorder in a Community Mental Health Setting: A Randomized Clinical Noninferiority Trial,” and abstract appeared Sept. 1 in JAMA Psychiatry.
JAMA Psychiatry. 2016 Sep 1;73(9):904-11. doi: 10.1001/jamapsychiatry.2016.1720.
Comparative Effectiveness of Cognitive Therapy and Dynamic Psychotherapy for Major Depressive Disorder in a Community Mental Health Setting: A Randomized Clinical Noninferiority Trial.
Connolly Gibbons MB1, Gallop R1, Thompson D2, Luther D2, Crits-Christoph K1, Jacobs J1, Yin S1, Crits-Christoph P1.
DESIGN, SETTING, AND PARTICIPANTS:
MAIN OUTCOMES AND MEASURES:
CONCLUSIONS AND RELEVANCE:
clinicaltrials.gov Identifier: NCT01207271.