Impact of interactions between drugs and laboratory test results on diagnostic test interpretation—a systematic review.

van Balveren JA, Verboeket-van de Venne WPHG, Erdem-Eraslan L, et al; Dutch Society for Clinical Chemistry and Laboratory Medicine, Task Group 'SMILE': Signaling Medication Interactions and Laboratory test Expert system. Clin Chem Lab Med. 2018;56:2004-2009.

This review article describes drug–laboratory test interactions, in which medications can affect test results and impede diagnosis. Although the quality of studies varies, researchers identified a potential benefit of clinical decision support to inform ordering clinicians about these potential interactions.

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