miércoles, 6 de febrero de 2019

Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial. | Anesthesiology | JAMA | JAMA Network

Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major Surgery: The ENGAGES Randomized Clinical Trial. | Anesthesiology | JAMA | JAMA Network

Morning Rounds

Megan Thielking



Meticulous monitoring doesn't curb risk of post-surgery delirium

One in four older adults experience delirium in the days after they undergo big surgeries. Doctors had hoped that keeping a close watch on brain activity during surgery and tweaking anesthesia levels could reduce that risk — but a new study suggests that isn’t the case. Researchers randomly assigned more than 1,200 older surgical patients at a St. Louis hospital to one of two groups: standard care or meticulous brain monitoring and minimizing anesthesia levels as needed. There wasn’t any difference in delirium rates between the two groups. But there were fewer deaths in the first month after surgery in the close monitoring group, an area the researchers say warrants more research.

Effect of Electroencephalography-Guided Anesthetic Administration on Postoperative Delirium Among Older Adults Undergoing Major SurgeryThe ENGAGES Randomized Clinical Trial

JAMA. 2019;321(5):473-483. doi:10.1001/jama.2018.22005

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