The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention | BMC Pharmacology and Toxicology | Full Text

The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention | BMC Pharmacology and Toxicology | Full Text

The impact of cytochrome 450 and Paraoxonase polymorphisms on clopidogrel resistance and major adverse cardiac events in coronary heart disease patients after percutaneous coronary intervention

Clopidogrel is an inactive prodrug, it catalyzed into its active form by Cytochrome 450 and Paraoxonase-1(PON-1). polymorphisms of genes encoding these enzymes will affect the efficacy of Clopidogrel. The main...

Authors:Zhaowei Zhang, Mingxiao Chen, Long Zhang and Qiang Zhao

Citation:BMC Pharmacology and Toxicology 2020 21:1

Content type:Research article

Published on: 3 January 2020

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