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1. Danish Evaluation of Your Heart Forecast (DANY): study protocol for a cluster randomised controlled trial on an interactive risk-communication tool aimed at improving adherence of patients with high blood pressure

   Authors:Anders Elkær Jensen, Jens Søndergaard, Niels Kristian Kjær, Rod Jackson and Jesper Bo Nielsen

   Content type:Study protocol

   3 January 2020

2. Estimating dose-response for time to remission with instrumental variable adjustment: the obscuring effects of drug titration in Genome Based Therapeutic Drugs for Depression Trial (GENDEP): clinical trial data

   Authors:Jennifer Hellier, Richard Emsley and Andrew Pickles

   Content type:Methodology

   3 January 2020

3. Behavioral Economics Incentives to Support HIV Treatment Adherence (BEST): Protocol for a randomized controlled trial in Uganda

   Authors:Sebastian Linnemayr, Chad Stecher, Uzaib Saya, Sarah MacCarthy, Zachary Wagner, Larissa Jennings and Barbara Mukasa

   Content type:Study protocol

   3 January 2020

4. Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial

   Authors:Yaseen M. Arabi, Ayed Y. Asiri, Abdullah M. Assiri, Hani A. Aziz Jokhdar, Adel Alothman, Hanan H. Balkhy, Sameera AlJohani, Shmeylan Al Harbi, Suleiman Kojan, Majed Al Jeraisy, Ahmad M. Deeb, Ziad A. Memish, Sameeh Ghazal, Sarah Al Faraj, Fahad Al-Hameed, Asim AlSaedi…

   Content type:Update

   3 January 2020

   The Study protocol to this article has been published in Trials 2018 19:81

5. Pre-operative anxiolysis in children through a combined pharmacological therapy with hydroxyzine and a non-pharmacological distraction technique with a clown (SONRISA): study protocol for randomised double-blind clinical trial

   Authors:Esther Aleo Luján, Amanda Lopez-Picado, Ana Rivas, Belén Joyanes Abancens, Marina Laura Rodríguez Rojo, Patricia Fernández García, Carmen Soto Beauregard, Jaime Rodríguez Alarcón, Carlos González Perrino, Borja San Pedro de Urquiza, Eva Arias, Diamelis Rodriguez, Carmen Esteban Polonio and Maria José Torrejón

   Content type:Study protocol

   2 January 2020