Biobanks and Electronic Medical Records: Enabling Cost-Effective Research

Sci Transl Med 30 April 2014: 
Vol. 6, Issue 234, p. 234cm3 
Sci. Transl. Med. DOI: 10.1126/scitranslmed.3008604

• COMMENTARY

PHARMACOGENOMICS

Biobanks and Electronic Medical Records: Enabling Cost-Effective Research

1. Erica Bowton1,*, 
2. Julie R. Field1, 
3. Sunny Wang1, 
4. Jonathan S. Schildcrout2, 
5. Sara L. Van Driest3,
6. Jessica T. Delaney4, 
7. James Cowan1, 
8. Peter Weeke4, 
9. Jonathan D. Mosley4, 
10. Quinn S. Wells4,
11. Jason H. Karnes4, 
12. Christian Shaffer4, 
13. Josh F. Peterson4,5, 
14. Joshua C. Denny4,5, 
15. Dan M. Roden4,6 and
16. Jill M. Pulley7

+Author Affiliations

1. ¹Institute for Clinical and Translational Research, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
2. ²Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
3. ³Department of Pediatrics, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
4. ⁴Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
5. ⁵Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
6. ⁶Department of Clinical Pharmacology, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
7. ⁷Department of Medical Administration, School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.

1. ↵*Corresponding author. E-mail: erica.bowton@vanderbilt.edu

Abstract

The use of electronic medical record data linked to biological specimens in health care settings is expected to enable cost-effective and rapid genomic analyses. Here, we present a model that highlights potential advantages for genomic discovery and describe the operational infrastructure that facilitated multiple simultaneous discovery efforts.

• Copyright © 2014, American Association for the Advancement of Science

Citation: E. Bowton, J. R. Field, S. Wang, J. S. Schildcrout, S. L. Van Driest, J. T. Delaney, J. Cowan, P. Weeke, J. D. Mosley, Q. S. Wells, J. H. Karnes, C. Shaffer, J. F. Peterson, J. C. Denny, D. M. Roden, J. M. Pulley, Biobanks and Electronic Medical Records: Enabling Cost-Effective Research. Sci. Transl. Med. 6, 234cm3 (2014).

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