BMC Bioinformatics
VOLUME 17 SUPPLEMENT 14
Proceedings of the 14th Annual Research in Computational Molecular Biology (RECOMB) Comparative Genomics Satellite Workshop: bioinformatics
Research
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.
Montreal, Canada
11-14 October 2016
Related articles have been published in a supplement to BMC Genomics.
- RESEARCH
Fast ancestral gene order reconstruction of genomes with unequal gene content
During evolution, genomes are modified by large scale structural events, such as rearrangements, deletions or insertions of large blocks of DNA. Of particular interest, in order to better understand how this t...BMC Bioinformatics 2016 17(Suppl 14):413Published on: 11 November 2016 - RESEARCH
Reconstructing ancestral gene orders with duplications guided by synteny level genome reconstruction
Reconstructing ancestral gene orders in the presence of duplications is important for a better understanding of genome evolution. Current methods for ancestral reconstruction are limited by either computationa...BMC Bioinformatics 2016 17(Suppl 14):414Published on: 11 November 2016 - RESEARCH
Comparative genomics meets topology: a novel view on genome median and halving problems
Genome median and genome halving are combinatorial optimization problems that aim at reconstruction of ancestral genomes by minimizing the number of evolutionary events between them and genomes of the extant s...BMC Bioinformatics 2016 17(Suppl 14):418Published on: 11 November 2016 - RESEARCH
Genome rearrangements with indels in intergenes restrict the scenario space
Given two genomes that have diverged by a series of rearrangements, we infer minimum Double Cut-and-Join (DCJ) scenarios to explain their organization differences, coupled with indel scenarios to explain their...BMC Bioinformatics 2016 17(Suppl 14):426Published on: 11 November 2016 - RESEARCH
A continuous analog of run length distributions reflecting accumulated fractionation events
We propose a new, continuous model of the fractionation process (duplicate gene deletion after polyploidization) on the real line. The aim is to infer how much DNA is deleted at a time, based on segment length...BMC Bioinformatics 2016 17(Suppl 14):412Published on: 11 November 2016 - RESEARCH
An analytical upper bound on the number of loci required for all splits of a species tree to appear in a set of gene trees
Many methods for species tree inference require data from a sufficiently large sample of genomic loci in order to produce accurate estimates. However, few studies have attempted to use analytical theory to qua...BMC Bioinformatics 2016 17(Suppl 14):417Published on: 11 November 2016 - RESEARCH
On the consistency of orthology relationships
Orthologs inference is the starting point of most comparative genomics studies, and a plethora of methods have been designed in the last decade to address this challenging task. In this paper we focus on the p...BMC Bioinformatics 2016 17(Suppl 14):416Published on: 11 November 2016 - RESEARCH
Probabilistic inference of lateral gene transfer events
Lateral gene transfer (LGT) is an evolutionary process that has an important role in biology. It challenges the traditional binary tree-like evolution of species and is attracting increasing attention of the m...BMC Bioinformatics 2016 17(Suppl 14):431Published on: 11 November 2016 - RESEARCH
In the light of deep coalescence: revisiting trees within networks
Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and a...BMC Bioinformatics 2016 17(Suppl 14):415Published on: 11 November 2016
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