Ethical, Legal and Social Issues (ELSI) - Genome editing [NEW TOPIC PAGE]

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The CRISPR-baby scandal: what’s next for human gene-editing As concerns surge after a bombshell revelation, here are four questions about this fast-moving field.
Gene Editing and Ethics B McIntosh, Harvard Magazine, Spring 2019
What we risk as humans if we allow gene-edited babies: a philosopher’s view  J Thompson, The Conversation, February 18, 2019
A framework for responsibility Nature Medicine, February 6, 2019
Should Scientists Toy With the Secret to Life? The gene-editing technology Crispr has the power to remake life as we know it. Questions about how to use it concern everyone.  New York Times Editorial Board, January 28, 2019
Perspectives on gene editing The Harvard Gazette, January 9, 2019
Human genome editing: ask whether, not how. Hurlbut J Benjamin et al. Nature 2019 565(7738) 135 Similar articles in PubMed
Experiments that led to the first gene-edited babies: the ethical failings and the urgent need for better governance. Li Jing-Ru et al. Journal of Zhejiang University. Science. B 20(1) 32-38 Similar articles in PubMed
A CRISPR focus on attitudes and beliefs toward somatic genome editing from stakeholders within the sickle cell disease community. Persaud Anitra et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Dec Similar articles in PubMed
Can the Thought of Teilhard de Chardin Carry Us Past Current Contentious Discussions of Gene Editing Technologies? Šuleková Mária et al. Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees 2019 Jan 28(1) 62-75 Similar articles in PubMed
Human genome editing: ask whether, not how JB Hurlbut, Nature, January 2, 2019
Human genome editing – the issues explored Sanger Institute, December 20, 2018
Wake-up call from Hong Kong VJ Dzau et al, Science, December 14, 2018
Scientists Say Gene-Edited Babies Claim Is 'Wake-Up Call' For World R Stein, NPR, December 13, 2018
Baby gene edits could affect a range of traits D Cyranoski, Nature News, December 12, 2018
Ethical issues plagued newly surfaced paper by ‘CRISPR babies’ scientist S Begley, Stat News, December 10, 2018
The Ethics of Heritable Genome Editing-New Considerations in a Controversial Area Adashi EY et al, JAMA,December 3, 2018
How to respond to CRISPR babies- The claims from He Jiankui that he has used gene editing to produce twin girls demand action. A new registry of research is a good start Nature editorial, December 5, 2018
Why Are Scientists So Upset About the First Crispr Babies? G Kolata et al, New York Times, December 5, 2018
We need a temporary moratorium on using gene editing to create babies P Knoepfler, Stat News, November 3, 2018
Beyond safety questions, gene editing will force us to deal with a moral quandary J Johston, Stat News, November 2018
Genetically Modified People Are Walking Among Us C Zimmer, NY Times, December 2, 2018
First CRISPR babies: 6 questions that remain D Cyranoski, Nature, November 30, 2018
NIH director says there’s work to do on regulating genome editing globally L Fatcher, Stat News, November 29, 2018
The era of human gene-editing may have begun. Why that is worrying The Economist, December 1, 2018
After such knowledge D Lowe, Science, November 28, 2018
Statement on Claim of First Gene-Edited Babies by Chinese Researcher NIH director, November 28, 2018
The Implications of CRISPR-Cas9 Genome Editing for IR. Perkons Nicholas R et al. Journal of vascular and interventional radiology : JVIR 2018 29(9) 1264-1267.e1 Similar articles in PubMed
How the genome-edited babies revelation will affect research D Cyranoski, Nature, November 27, 2018
Facing Backlash, Chinese Scientist Defends Gene-Editing Research On Babies R Stein, NPR, Morning Edition, November 28, 2018
Sparse public data on CRISPR’d embryos leave many questions unanswered S Begley et al, Stat News, November 27, 2018
The Implications of Experimenting with Genetically Edited Babies M Specter, New Yorker, November 27, 2018
Editing Babies? We Need to Learn a Lot More First E Topol, NY Times, November 27, 2018
Genome-edited baby claim provokes international outcry D Cyranoski, Nature, November 26, 2018
Use the patent system to regulate gene editing S. Parthasaraty, Nature, October 23, 2018
Ethical Issues Regarding CRISPR Mediated Genome Editing. Shinwari Zabta Khan et al. Current issues in molecular biology 2018 26103-110 Similar articles in PubMed
Science and Bioethics of CRISPR-Cas9 Gene Editing: An Analysis Towards Separating Facts and Fiction. Cribbs Adam P et al. The Yale journal of biology and medicine 2017 90(4) 625-634 Similar articles in PubMed
The Human Genome Editing Race: Loosening Regulatory Standards for Commercial Advantage? Cathomen Toni et al. Trends in biotechnology 2018 Jul Similar articles in PubMed
Broad societal debate should inform the use of genome editing in reproduction S Griffin, BMJ, July 23, 2018
Genome editing and human reproduction: social and ethical issues Nuffield Council on Bioethics, July 2018
Genome Editing in Humans Wellcome Sanger Institute
Human genome editing is not unethical, says Nuffield Council N Hawkes, BMJ, July 17, 2018
FDA’s New Efforts to Advance Biotechnology Innovation S Gotlieb et al, FDA Blog, June 6, 2018
CRISPR ethics: Moral considerations for applications of a powerful tool. Brokowski Carolyn et al. Journal of molecular biology 2018 Jun Similar articles in PubMed
Interested in responsible gene editing? Join the (new) club M Enserink, Science Magazine, Mar 28, 2018
Gene Editing in Humans: Towards a Global and Inclusive Debate for Responsible Research . de Lecuona Itziar et al. The Yale journal of biology and medicine 2017 Dec 90(4) 673-681 Similar articles in PubMed
Ethics and Genetics: Examining a Crossroads in Nursing Through a Case Study . Curr Beamer Laura Curr et al. Clinical journal of oncology nursing 2017 Dec 21(6) 730-737 Similar articles in PubMed
The ethics of genome editing in the clinic: A dose of realism for healthcare leaders. Bubela Tania et al. Healthcare management forum 2017 May 30(3) 159-163 Similar articles in PubMed
Take stock of research ethics in human genome editing. Nature 2017 0 0. (7672) 307.Nature 2017 0 0. (7672) 307 Similar articles in PubMed
Genome editing: science, ethics, and public engagement Lancet, August 11, 2017
U.S. attitudes on human genome editing. Scheufele Dietram A et al. Science (New York, N.Y.) 2017 Aug 357(6351) 553-554 Similar articles in PubMed
Genome Editing National Human Genome Research Institute, 2017
Genome editing: Bioethics shows the way. Neuhaus Carolyn P et al. PLoS biology 2017 Mar 15(3) e2001934 Similar articles in PubMed
The ethics of genome editing: where now? L Blackburn, PHG Foundation, October 2016
Ethical and regulatory aspects of genome editing. Kohn Donald B et al. Blood 2016 Apr Similar articles in PubMed
Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement. Chan Sarah et al. The American journal of bioethics : AJOB 2015 Dec 15(12) 42-7 Similar articles in PubMed
Germ line genome editing in clinics: the approaches, objectives and global society. Ishii Tetsuya et al. Briefings in functional genomics 2015 Nov Similar articles in PubMed
Human Genome Editing and Ethical Considerations. Krishan Kewal et al. Sci Eng Ethics 2015 Jul 8. Similar articles in PubMed
Germline genome-editing research and its socioethical implications. Ishii Tetsuya et al. Trends Mol Med 2015 Jun 9. Similar articles in PubMed