Extending evidence-based medicine

Extending evidence-based medicine

Edited by: Prof Trisha Greenhalgh

The science of evidence-based medicine (EBM) is more than 20 years old. Unsurprisingly the movement has produced both an established orthodoxy and dissenting voices. This series of papers, whose authors include both ‘orthodox’ and ‘dissenting’ perspectives, considers how EBM might be extended beyond the epidemiological focus of its founding fathers. We invite comments from readers and anticipate that this series will provoke an important contemporary debate on what EBM is and what it should become.

Collection published in: Trials, BMC Medicine, BMC Medical Ethics.

1. Content Type:Debate

   The importance of values in evidence-based medicine

   Evidence-based medicine (EBM) has always required integration of patient values with ‘best’ clinical evidence. It is widely recognized that scientific practices and discoveries, including those of EBM, are val...

   Authors:Michael P. Kelly, Iona Heath, Jeremy Howick and Trisha Greenhalgh

   Citation:BMC Medical Ethics 2015 16:69

   Published on: 12 October 2015

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2. Content Type:Review

   Randomised trials in context: practical problems and social aspects of evidence-based medicine and policy

   Randomised trials can provide excellent evidence of treatment benefit in medicine. Over the last 50 years, they have been cemented in the regulatory requirements for the approval of new treatments. Randomised ...

   Authors:Warren Pearce, Sujatha Raman and Andrew Turner

   Citation:Trials 2015 16:394

   Published on: 1 September 2015

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3. Content Type:Debate

   Six ‘biases’ against patients and carers in evidence-based medicine

   Evidence-based medicine (EBM) is maturing from its early focus on epidemiology to embrace a wider range of disciplines and methodologies. At the heart of EBM is the patient, whose informed choices have long be...

   Authors:Trisha Greenhalgh, Rosamund Snow, Sara Ryan, Sian Rees and Helen Salisbury

   Citation:BMC Medicine 2015 13:200

   Published on: 1 September 2015

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4. Content Type:Opinion

   Trustworthy guidelines – excellent; customized care tools – even better

   The ability to do online searches for health information has led to concerns that patients find the results confusing and that they often lead to expectations for treatments that have little supportive evidenc...

   Authors:Glyn Elwyn, Casey Quinlan, Albert Mulley, Thomas Agoritsas, Per Olav Vandvik and Gordon Guyatt

   Citation:BMC Medicine 2015 13:199

   Published on: 1 September 2015

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