sábado, 19 de noviembre de 2011

Translational bioinformatics: ... [J Am Med Inform Assoc. 2011 Jul-Aug] - PubMed - NCBI

J Am Med Inform Assoc. 2011 Jul-Aug;18(4):354-7. Epub 2011 May 10.

Translational bioinformatics: linking knowledge across biological and clinical realms.

Source

Center for Clinical and Translational Science, University of Vermont, Burlington, Vermont 05405, USA. neil.sarkar@uvm.edu

Abstract

Nearly a decade since the completion of the first draft of the human genome, the biomedical community is positioned to usher in a new era of scientific inquiry that links fundamental biological insights with clinical knowledge. Accordingly, holistic approaches are needed to develop and assess hypotheses that incorporate genotypic, phenotypic, and environmental knowledge. This perspective presents translational bioinformatics as a discipline that builds on the successes of bioinformatics and health informatics for the study of complex diseases. The early successes of translational bioinformatics are indicative of the potential to achieve the promise of the Human Genome Project for gaining deeper insights to the genetic underpinnings of disease and progress toward the development of a new generation of therapies.

PMID:
21561873
[PubMed - indexed for MEDLINE]
PMCID: PMC3128415
Free PMC Article
Translational bioinformatics: ... [J Am Med Inform Assoc. 2011 Jul-Aug] - PubMed - NCBI

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