- 02 Apr 2017 Ebola update (13): news, treatment, research, funding
- 02 Apr 2017 Lassa fever - West Africa (14): Nigeria
- 02 Apr 2017 Chikungunya - Nepal
- 02 Apr 2017 Botulism - USA: (CA) wound, non-drug-related
- 02 Apr 2017 Typhoid fever - Zimbabwe (02): (HA)
- 02 Apr 2017 Undiagnosed deaths, illnesses, canine - UK: (DB)
- 02 Apr 2017 Hepatitis A - Portugal: (LI) MSM
- 02 Apr 2017 Cholera, diarrhea & dysentery update (11): Africa, Asia
- 02 Apr 2017 MERS-CoV (19): Saudi Arabia (SH, QS)
- 02 Apr 2017 Foodborne illness - India: (KL) police, fish curry, RFI
- 02 Apr 2017 Meningitis, meningococcal - Nigeria (03): fatal, more states, vaccine short, RFI
- 02 Apr 2017 Japanese encephalitis & other - India (02): (BR)
- 02 Apr 2017 Filariasis - Marshall Islands: elimination
- 02 Apr 2017 Avian influenza, human (40): Egypt (FY), H5N1, comments
- 02 Apr 2017 Bovine tuberculosis - USA (06): (SD): new strain from Mexico
- 02 Apr 2017 Streptococcus, group A - Canada: (ON) fatal, homeless shelter, RFI
- 02 Apr 2017 Yellow fever - Americas (35): Brazil, vaccine, monkeys
- 02 Apr 2017 Foodborne illness - Lebanon: (BA) schoolchildren, RFI
- 01 Apr 2017 E. coli EHEC - USA (05): O157, soynut butter, CDC update
- 01 Apr 2017 E. coli EHEC - Canada (05): O121, flour
- 01 Apr 2017 Measles update (16)
- 31 Mar 2017 Avian influenza (87): Viet Nam, backyard, HPAI H5N1, H5N6, control
- 31 Mar 2017 MERS-CoV (18): Africa, animal reservoir, camels, 2015, research
- 31 Mar 2017 Avian influenza, human (39): China, H7N9
- 31 Mar 2017 Foot & mouth disease - Algeria (02): (RE) bovine, st A, new strain, OIE
- 31 Mar 2017 Leishmaniasis, visceral - Egypt (02): (BH) prison inmate
- 30 Mar 2017 Pink snow mould, wheat - USA: (WA)
- 30 Mar 2017 Yellow fever - The Netherlands: ex Suriname, WHO
- 30 Mar 2017 Foot & mouth disease - Algeria: (RE) bovine, susp, RFI
- 30 Mar 2017 Infectious salmon anemia - Faroe Islands (02): (NO) st HPR-deleted, OIE
- 30 Mar 2017 Kyasanur Forest disease - India (06): (KA) new cases
- 30 Mar 2017 Undiagnosed deaths, avian - UK: (Scotland) 2014, toxin found
- 30 Mar 2017 Rabies (16): Asia (Philippines) animal, human
- 30 Mar 2017 Bovine tuberculosis - USA (05): (MI) bovine
- 30 Mar 2017 Mumps update (14): Australia (QL), USA
- 30 Mar 2017 Lead poisoning - USA: (CA) children
- 30 Mar 2017 Syphilis - USA: (NC) increased incidence, ocular, HIV-coinfection
- 30 Mar 2017 Mosaic disease, cassava - Malawi
- 29 Mar 2017 Infectious salmon anemia - Faroe Islands: (NO)
- 29 Mar 2017 Measles update (15)
- 29 Mar 2017 Rabbit hemorrhagic disease - Australia: (AC) wild, RHDV1 K5, new strain, OIE
- 29 Mar 2017 Glanders, equine - India (02): (RJ)
- 29 Mar 2017 E. coli EHEC - Canada (04): O121, flour
- 29 Mar 2017 Meningitis, meningococcal - Cameroon: (Yaounde) fatal, sg W
- 29 Mar 2017 Bluetongue - Botswana: (KG) not typed, ovine, OIE
- 28 Mar 2017 Avian influenza (86): USA (GA) poultry, LPAI H7
- 28 Mar 2017 Toxic algae - UK: (England) warning
- 28 Mar 2017 Leptospirosis - USA (04): (NJ) canine
- 28 Mar 2017 Lumpy skin disease - Europe (02): Greece (PW) bovine, 1st 2017 outbreak, OIE
- 28 Mar 2017 Lassa fever - West Africa (13): update
- 28 Mar 2017 Botulism, avian - New Zealand: (WK) waterfowl
- 28 Mar 2017 Avian influenza (85): Europe, HPAI H5N8, poultry, international trade
- 28 Mar 2017 Legionellosis - Japan: (HS) hot spring bath
- 28 Mar 2017 Undiagnosed deaths, reptile - USA: (TN) zoo
- 28 Mar 2017 Undiagnosed deaths, avian - Japan: (Tokyo) crow
- 28 Mar 2017 Equine herpesvirus - North America (13): USA (OR) equine
- 28 Mar 2017 Beef thyroid hormone, dog food - North America (02): recall
- 28 Mar 2017 African swine fever - Europe (08): Moldova, Russia, domestic swine, OIE
- 28 Mar 2017 Leishmaniasis, visceral - Egypt: (Cairo) RFI
- 27 Mar 2017 MERS-CoV (17): Saudi Arabia (RI)
- 27 Mar 2017 Duck viral enteritis - USA: (OK) wild ducks
- 27 Mar 2017 Chikungunya (09): Asia (Pakistan)
- 27 Mar 2017 Lassa fever - West Africa (12): Nigeria
- 27 Mar 2017 Avian influenza, human (38): China, H7N9
- 27 Mar 2017 Rabies (15): Americas (USA, Canada)
- 27 Mar 2017 Anthrax - India (04): (OR) human, livestock susp
- 27 Mar 2017 Bacterial leaf blight, rice - Philippines: (NS)
- 26 Mar 2017 Varicella - India: (WB)
- 26 Mar 2017 Zika virus (05): Americas, Pacific, Asia, research, observations
- 26 Mar 2017 Avian influenza (84): USA, poultry, LPAI H7N9, HPAI H7N9
- 26 Mar 2017 Ebola update (12): news, research, vaccine
- 26 Mar 2017 Botulism - Romania: (BZ) canned food
- 26 Mar 2017 Yellow fever - Americas (34): Brazil
- 26 Mar 2017 Mumps update (13): Portugal, Canada, USA, analysis
- 25 Mar 2017 Meningitis, meningococcal - Nigeria (02): fatal, emergence sg C, WHO
- 25 Mar 2017 Undiagnosed rash - Cameroon (03): (EN) fatalities, commentary
- 25 Mar 2017 Tetanus - Australia: (NSW) unimmunized child
- 25 Mar 2017 Measles update (14)
- 25 Mar 2017 Norovirus - Canada (02): (BC)
- 25 Mar 2017 Avian influenza (83): Belgium (LI) wildfowl, HPAI H5N8, OIE
- 24 Mar 2017 Avian influenza (82): China (Hunan) HPAI H7N9, poultry, OIE
- 24 Mar 2017 Brucellosis - USA (02): (NY) swine, human, 2016
- 24 Mar 2017 Foodborne illness - Egypt (04): schoolchildren
- 24 Mar 2017 Hepatitis A - USA: (MI) increased incidence
- 24 Mar 2017 Avian influenza, human (37): China, H7N9, WHO update, control, genetics
- 24 Mar 2017 Crimean-Congo hem. fever - Namibia (03): (OH)
- 24 Mar 2017 New World screwworm - USA (02): (FL) successfully eradicated
- 24 Mar 2017 Sporotrichosis - Brazil: (RJ) feline-human zoonosis
- 24 Mar 2017 Mumps update (12): Canada (ON) USA (IL,AR)
- 24 Mar 2017 Lethal necrosis, maize - Malawi: alert
- 23 Mar 2017 Pigeon rotavirus - Australia: emerging, OIE
- 23 Mar 2017 Yellow fever - Americas (33): PAHO/WHO, Brazil
- 23 Mar 2017 Yellow fever - Americas (32): Brazil, monkey
- 23 Mar 2017 Cholera, diarrhea & dysentery update (10): Africa
- 23 Mar 2017 Yellow fever: vaccination comment
- 23 Mar 2017 Crimean-Congo hem. fever - Oman: case numbers
- 23 Mar 2017 Tetanus, obstetric - USA: (KY) unvaccinated woman
- 23 Mar 2017 Foodborne illness - Egypt (03): schoolchildren, RFI
- 23 Mar 2017 Canine distemper, wildlife - USA (02): (VI) raccoon, skunk, fox, susp.
- 23 Mar 2017 E. coli EHEC - Canada (03): O121
- 23 Mar 2017 Influenza (09): WHO global update
- 23 Mar 2017 Avian influenza (81): USA, poultry, LPAI H7N9, HPAI H7N9, RFI
- 23 Mar 2017 Hantavirus - Americas (23): Chile (LL)
- 23 Mar 2017 Undiagnosed rash - Cameroon (02): (EN) fatalities, commentary
- 23 Mar 2017 Pentobarbital, dog food - USA (03): recall
- 23 Mar 2017 Avian influenza (71): USA (WI): turkey, HPAI H7N9 NOT, LPAI H5N2 corr
- 22 Mar 2017 Murray Valley encephalitis - Australia: (WA), alert
- 22 Mar 2017 MERS-CoV (16): Qatar, Saudi Arabia (SH, MD, RI)
- 22 Mar 2017 Anthrax - Russia: (YN) reindeer vaccination programme
- 21 Mar 2017 Yellow fever - Americas (31): PAHO/WHO, Brazil
- 21 Mar 2017 Rabies (14): Europe (Hungary) caprine, OIE
- 21 Mar 2017 Brucellosis - Mexico: (ZA) unpasteurized cheese
- 21 Mar 2017 Malaria - South Africa, Botswana: high alert
- 21 Mar 2017 E. coli EHEC - Canada (02): O121, RFI
- 21 Mar 2017 Undiagnosed rash - Cameroon: (EN) fatalities, RFI
- 21 Mar 2017 Hepatitis - India: (KA) waterborne, RFI
- 21 Mar 2017 Brucellosis - USA: (NY) swine, human, 2016
- 21 Mar 2017 Cryptosporidiosis - Australia: (NS)
- 20 Mar 2017 Flavescence doree, grapevine - Switzerland: (VD)
- 20 Mar 2017 Distemper, canine - India: (KA)
- 20 Mar 2017 Dengue/DHF update (03): Asia, Pacific
- 20 Mar 2017 White nose syndrome, bats - North America (03): (NE) 1st report
- 20 Mar 2017 Anthrax - India (03): (OR) human, livestock susp
- 20 Mar 2017 Zika virus (04): Americas, Asia Europe, research, observations
- 20 Mar 2017 Anthrax - Australia (06): (VI) livestock, vaccination progress
- 20 Mar 2017 Avian influenza, human (36): China, H7N9
- 19 Mar 2017 Anthrax - India (02): (OR) human
- 19 Mar 2017 Rabies (13): Americas, El Salvador (CA) feline, OIE
- 19 Mar 2017 Mumps update (11): USA
- 19 Mar 2017 Lassa fever - West Africa (11): Nigeria
- 19 Mar 2017 Cryptosporidiosis - USA: (PA) petting farm
- 19 Mar 2017 Simian malaria - Brazil: (RJ) human cases
- 19 Mar 2017 Tick-borne encephalitis virus - Netherlands: (OV)
- 19 Mar 2017 Norovirus - USA (02): (CA)
- 19 Mar 2017 Measles update (13)
- 18 Mar 2017 Plague, animal - USA (02): (CO) prairie dog, alert
- 18 Mar 2017 Yellow fever - Americas (30): PAHO/WHO, Brazil, Netherlands ex Suriname
- 18 Mar 2017 Lead poisoning, shipyard workers - USA: (MN, WI)
- 18 Mar 2017 Cyanide poisoning - USA (ID): dog, child
- 18 Mar 2017 Beef thyroid hormone, dog food - North America: recall
- 18 Mar 2017 Bovine tuberculosis - USA (04): (SD) new strain from Mexico
- 18 Mar 2017 Salmonellosis - Denmark: fatalities, microwavable food
- 18 Mar 2017 Orthopoxvirus infection - USA: (AK)
- 18 Mar 2017 Meningitis, meningococcal - Nigeria: (SO, ZA) fatal, new sg.susp., RFI
- 18 Mar 2017 Avian influenza (80): Croatia (KZ), poultry HPAI H5N5, new strain, OIE
- 17 Mar 2017 Chemical weapons - Iraq: sulfur mustard, chlorine, 2016
- 17 Mar 2017 Murine typhus - USA: (TX) increase cases, geographic expansion, 2003-2013
- 17 Mar 2017 Undiagnosed virus - Egypt (02): comment, RFI
- 17 Mar 2017 Avian influenza (79): USA (TN): poultry, HPAI H7N9
- 17 Mar 2017 Undiagnosed poisoning - India: fatalities
- 17 Mar 2017 Anthrax - Philippines: (AB) human, bovine, susp
- 17 Mar 2017 Brainworm - USA: (MI) elk
- 17 Mar 2017 Salmonellosis, st Enteritidis - USA: restaurant chain, truffle oil, 2015
- 17 Mar 2017 Avian influenza, human (35): China, H7N9, WHO updates
- 17 Mar 2017 Strangles, equine - USA: (CO) alert
- 17 Mar 2017 Crimean-Congo hem. fever - Pakistan (02): (PB)
- 17 Mar 2017 Hantavirus update - Americas (22): Chile (AR)
- 17 Mar 2017 Avian influenza (78): USA poultry, (AL) H7, (TN) H7N9, both LPAI
- 17 Mar 2017 Avian influenza (77): USA (WI) turkey, LPAI H5N2
- 17 Mar 2017 Bovine tuberculosis - USA (03): (MI)
- 17 Mar 2017 Plum pox virus, peach - South Korea: 1st rep
- 17 Mar 2017 Canine distemper, wildlife - USA: (TX) raccoon
- 16 Mar 2017 Poliomyelitis update (03): Pakistan (GB, IS, PB), environmental samples, global
- 16 Mar 2017 White spot syndrome, prawn - Australia (03): (QL) update
- 16 Mar 2017 Anthracnose, soursop - Puerto Rico
- 16 Mar 2017 Hand, foot & mouth disease update (03): Pakistan (PB), comment
- 16 Mar 2017 Hepatitis A - EU: MSM
- 16 Mar 2017 Foodborne illness - Egypt (02): (SJ) schoolchildren
- 16 Mar 2017 Crimean-Congo hem. fever - Pakistan: (IS) susp, not
- 16 Mar 2017 Chikungunya (08): Asia (Pakistan)
- 16 Mar 2017 Foot & mouth disease - Palestinian Auth (02): (GZ) bovine, st O, spread
- 16 Mar 2017 Malaria - Namibia (02): (northern regions)
- 16 Mar 2017 Avian influenza, human (34): China (JX,CQ) H7N9
- 15 Mar 2017 Undiagnosed virus - Egypt: RFI
- 15 Mar 2017 Citrus tristeza virus - Malta ex Italy
- 15 Mar 2017 Monkeypox - Republic of Congo
- 15 Mar 2017 Pertussis update (01): Viet Nam, New Zealand
- 15 Mar 2017 Foodborne illness - Egypt: (SJ) schoolchildren, RFI
- 15 Mar 2017 Malaria - South Africa (03): (GT, NW) comment
- 15 Mar 2017 E. coli EHEC - USA (04): (OR) O157, soynut butter, preschool
- 15 Mar 2017 Anthrax - Australia (05): (VI) ovine, new outbreaks
- 15 Mar 2017 Legionellosis - Lithuania: (Vilnius) fatal
- 15 Mar 2017 White nose syndrome, bats - North America (02): (MN) population declines
- 15 Mar 2017 Hantavirus update - Americas (21): USA (WA) automobile air system susp
- 15 Mar 2017 Avian influenza (76): UK (Wales) wildfowl, HPAI H5N8, OIE
- 15 Mar 2017 Avian influenza, human (33): Indonesia (JR) H5 susp, RFI
- 14 Mar 2017 Hantavirus update - Americas (20): Chile (RM) susp.
- 14 Mar 2017 Undiagnosed disease - Colombia (02): (CE) fatal
- 14 Mar 2017 Poliomyelitis update (02): Pakistan (GB) WPV1
- 14 Mar 2017 Mumps update (10)
- 14 Mar 2017 Measles update (12)
- 14 Mar 2017 Foot & mouth disease - Jordan: multiple species, st. O, OIE
- 14 Mar 2017 Poliomyelitis update (01): Pakistan (GB) global, RFI
- 14 Mar 2017 Malaria - Burundi: national epidemic declared
- 14 Mar 2017 Malaria - Venezuela: (NE) autochthonous, extension of national epidemic
- 14 Mar 2017 Foodborne illness - South Africa: (EC) nursing home, fatal, RFI
- 14 Mar 2017 Cutaneous & renal glomerular vasculopathy, canine - UK (02): (England)
- 13 Mar 2017 Cholera, diarrhea & dysentery update (09): Africa
- 13 Mar 2017 Avian influenza (75): Nepal (ON) H5N8 poultry, H5N1 captive bird, OIE
- 13 Mar 2017 Avian influenza (74): Viet Nam (CB, HT) backyard, HPAI H5N1, H5N6, spread
- 13 Mar 2017 Anthrax - Australia (04): (VI) ovine, new outbreak
- 13 Mar 2017 Malaria - South Africa (02): (GT,NW)
- 13 Mar 2017 Devil facial tumor, Tasmanian devil - Tasmania: possible cure
- 13 Mar 2017 Yellow fever - Americas (29): PAHO/WHO, Brazil (RJ)
- 12 Mar 2017 Lassa fever - West Africa (10): Benin, Togo, Burkina Faso
- 12 Mar 2017 Ebola update (11): news, vaccine, research
- 12 Mar 2017 Listeriosis - USA (02): fatal, unpast soft cheese, aged 60 days, recall
- 12 Mar 2017 Mumps update (09)
- 12 Mar 2017 Candida auris - USA
- 12 Mar 2017 Herpes simplex type 1, genital - USA: (NYC) circumcision
- 12 Mar 2017 Salmonellosis, st Typhimurium - Spain: (MD) playground sand, 2016
- 12 Mar 2017 Crimean-Congo hem. fever - Namibia (02): (OH)
- 12 Mar 2017 Equine coronavirus - USA: (CA)
- 12 Mar 2017 Anthrax - Tanzania: (KL) bovine, human
- 12 Mar 2017 Anthrax - Australia (03): (VI) bovine, susp
- 12 Mar 2017 Toxic tea, aconitine - USA: (CA)
- 12 Mar 2017 MERS-CoV (15): Saudi Arabia (RI, MK) nosocomial outbreak, WHO, RFI
- 12 Mar 2017 Glanders, equine - India: (MP)
- 11 Mar 2017 Avian influenza (73): Taiwan (TA) poultry, HPAI, H5N2, H5N6, H5N8, spread
- 11 Mar 2017 African swine fever - Europe (07): Moldova (SO) domestic swine, OIE
- 11 Mar 2017 Avian influenza (72): USA (TN) poultry, LPAI H7N9, OIE
- 11 Mar 2017 BSE, bovine - Spain: (CL) atypical L-type, OIE
- 11 Mar 2017 Avian influenza (71): USA (WI) turkey, HPAI H7N9
- 11 Mar 2017 Listeriosis - USA: fatal, unpast soft cheese, recall
- 10 Mar 2017 Rabies (12): Europe (Hungary) fox, OIE
- 10 Mar 2017 Malaria - South Africa: (GT)
- 10 Mar 2017 Avian influenza, human (32): China, H7N9
- 09 Mar 2017 Measles update (11)
- 09 Mar 2017 Hepatitis C - USA (02): (TX) reused saline flush syringes, 2015
- 09 Mar 2017 Coronavirus - China: (HK) OC43 outbreak
- 09 Mar 2017 Peste des petits ruminants - Mongolia (03): (HD) saiga antelope
- 09 Mar 2017 Avian influenza (70): Malaysia (KN) H5N1, poultry, OIE
- 09 Mar 2017 Undiagnosed disease - Colombia: (CE) fatal, RFI
- 09 Mar 2017 Avian influenza (69): USA (TN) poultry, HPAI H7N9
- 09 Mar 2017 Zika virus (03): Americas, research
- 08 Mar 2017 Cholera, diarrhea & dysentery update (08): Asia (Yemen)
- 08 Mar 2017 E. coli EHEC - USA (03): O157, soynut butter, more cases, recall
- 08 Mar 2017 Avian influenza, human (31): Russia (MS) H5N8 susp, RFI
- 08 Mar 2017 New in IJID (03): March 2017. TB issue
- 08 Mar 2017 Bovine tuberculosis - UK: (England) canine, camelid
- 08 Mar 2017 Foot & mouth disease - South Africa: (MP) bovine, st pending, OIE
- 08 Mar 2017 Undiagnosed illness - Nigeria: (ZA) fatal, RFI
- 07 Mar 2017 Avian influenza, human (30): China, H7N9
- 07 Mar 2017 Ross River virus - Australia (05): (NS)
- 07 Mar 2017 Avian influenza (68): USA (WI) poultry, LPAI H5N2, OIE
- 07 Mar 2017 Anthrax - Australia (02): (QL) bovine
- 07 Mar 2017 Yellow fever - Americas (28): Brazil (ES) WHO, travel advice
- 07 Mar 2017 Newcastle disease - Pakistan: (SD) peacock
- 07 Mar 2017 E. coli EHEC - USA (02): O157, soynut butter
- 07 Mar 2017 Kyasanur Forest disease - India (05): (GA,MH) monkey
- 07 Mar 2017 Avian influenza (67): USA (TN) poultry, HPAI H7, OIE
- 06 Mar 2017 Blast disease, wheat - India: 1st rep (WB)
- 06 Mar 2017 Hemorrhagic septicemia - Israel: (HZ) bovine, OIE
- 06 Mar 2017 MERS-CoV (14): Saudi Arabia
- 06 Mar 2017 Anthrax - Australia: (VI) ovine, human exp
- 06 Mar 2017 Kyasanur Forest disease - India (04): (GA) vaccine impact
- 05 Mar 2017 Avian influenza (66): USA (TN) poultry, HPAI, H7
- 05 Mar 2017 Meningitis, meningococcal - USA: (OR) college, sg B, sg B vaccine, RFI
- 05 Mar 2017 Ebola update (10): news, research
- 05 Mar 2017 Chemical weapons - Syria: chlorine, sarin gas, blistering agent
- 05 Mar 2017 Undiagnosed respiratory disease (03): China (Hong Kong) comment, RFI
- 05 Mar 2017 Mumps update (08): Canada, USA, comment
- 05 Mar 2017 Avian influenza (65): Greece (EM) poultry, HPAI H5N6, clarification
- 05 Mar 2017 Ross River virus - Australia (04): (WA)
- 05 Mar 2017 Bovine tuberculosis - USA (02): (SD)
- 04 Mar 2017 Yellow fever - Americas (27): Peru (AY)
- 04 Mar 2017 American foulbrood, apis - USA: (HI)
- 04 Mar 2017 Avian influenza (64): (Europe) HPAI H5N8, poultry, wildfowl, EU update
- 04 Mar 2017 Avian influenza, human (29): China (SH, Mainland), H7N9, WHO assessment
- 04 Mar 2017 Undiagnosed respiratory disease (02): China (Hong Kong) comment
- 04 Mar 2017 Yellow fever - Americas (26): PAHO/WHO
- 04 Mar 2017 Avian influenza (63): Greece,Bosnia/Herzegovina poultry,birds HPAI H5N8 H5N6 OIE
- 03 Mar 2017 Quick & slow wilts, black pepper - Viet Nam: (DO) susp
- 03 Mar 2017 Mumps update (07): Canada, USA
- 03 Mar 2017 Hand, foot & mouth disease update (02): Thailand, Viet Nam
- 03 Mar 2017 Measles update (10)
- 03 Mar 2017 Undiagnosed respiratory disease: China (Hong Kong) RFI
Published Date: 2017-04-02 22:18:48
Subject: PRO/AH/EDR> Ebola update (13): news, treatment, research, funding
Archive Number: 20170402.4943034
Subject: PRO/AH/EDR> Ebola update (13): news, treatment, research, funding
Archive Number: 20170402.4943034
EBOLA UPDATE (13): NEWS, TREATMENT, RESEARCH, FUNDING
*****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this update:
News
Documentary
Treatment
Convalescent plasma
Research
Chimpanzee vaccine
Funding
Sierra Leone
******
30 Mar 2017: Survivors remember Ebola epidemic as Samaritan's Purse releases documentary
http://www.deseretnews.com/article/865676776/Survivors-remember-Ebola-epidemic-as-Samaritan7s-Purse-releases-documentary.html
[Rev. Franklin Graham recounts the story in "Facing Darkness," a documentary produced by Samaritan's Purse recounting its fight to save the 1st American doctor diagnosed with Ebola [Ebola virus disease (EVD)] during the epidemic in West Africa. The film debuts in select theaters on Thursday [30 Mar 2017] and will return for encore showings on 10 Apr 2017.]
[This doctor, KB, was director of the Ebola treatment unit at ELWA (Eternal Love Winning Africa) Hospital when he was infected with the virus. - Mod.LK]
Treatment
----------
Citation. Burnouf T, Dhe JM, Abayomi A (30 Mar 2017). Convalescent Plasma and the Dose of Ebola Virus Antibodies. N Engl J Med 2017; 376:1296-1297 DOI: 10.1056/NEJMc1700090
[Letter to the editor:
After the clinical evaluation of convalescent plasma for Ebola virus (EBOV) disease in Guinea, van Griensven and colleagues [van Griensven J, Edwards T, de Lamballerie X, et al. Evaluation of convalescent plasma for Ebola virus disease in Guinea. N Engl J Med 2016;374:33-42] now provide additional data showing that the dose of neutralizing antibodies in the donations was low and that there was no apparent association between the dose of neutralizing antibodies and human survival. [van Griensven J, Edwards T, Baize S. Efficacy of convalescent plasma in relation to dose of Ebola virus antibodies. N Engl J Med 2016;375:2307-2309]. In our opinion, it is essential that the authors clarify precisely the stage of the procedure at which samples for neutralizing antibodies were taken. Was it at the time of plasma donation, after pathogen-inactivation treatment, or at the time of transfusion (after 40 days of storage, a delay that may possibly affect the efficacy of antibodies)? This information is critical because there is no publicly accessible documentation regarding the estimated effect that handling convalescent plasma processes have on the stability and activity of neutralizing EBOV antibodies. It is also important that the authors document how samples for antibody assessment were handled. This will help in defining standards required for handling convalescent plasma against emerging infectious agents in regions with limited available technology.
Reply by the author and colleagues: We thank Burnouf et al. for the pertinent questions. Donor samples sent to France for EBOV antibody testing were peripheral-blood samples collected on the day that donors came for automated plasma collection. These blood samples had not undergone pathogen reduction, because this process was applied only to the plasma bags collected for administration. The blood samples were stored at -30 deg C [-22 deg F] in Guinea, shipped on dry ice to the biosafety level 4 laboratory in France, and stored at 80 deg C [-112 deg F]. Samples had been thawed twice when antibody testing was done. Most of the plasma used in the trial was administered shortly after collection; the median time of plasma storage before administration was 8 days (interquartile range, 4 to 15). Plasma was stored for clinical use at 2 to 8 deg C [36 to 46 deg F] for up to 40 days and frozen at -30 deg C [-22 deg F] after that. We used a pathogen-reduction process, because when this study was conducted, there were many gaps in our knowledge of EBOV persistence and the presence of other transfusion-transmissible infections that could not be excluded under field conditions. Recently, Geisen et al. reported in a single donor that levels of IgG protein, EBOV IgG, and neutralizing antibodies were only slightly reduced after pathogen-reduction treatment with S59 amotosalen-ultraviolet A. We agree that more research is needed on the potential effect of pathogen reduction on the stability and activity of anti-EBOV neutralizing antibodies. (J van Griensven, P Gallian, X de Lamballerie for the Ebola-Tx Consortium)]
[See full report with references at DOI cited above. - Mod.LK]
[Information on the pathogen inactivator S59 amotosalen can be found here: https://www.ncbi.nlm.nih.gov/pubmed/12534321 - Mod.JH]
Research
------
2 Apr 2017 The trick to saving chimps from Ebola
https://www.thestar.com/news/insight/2017/04/02/the-trick-to-saving-chimps-from-ebola.html
[A new study has shown great promise for an oral Ebola vaccine for chimpanzees and gorillas. But limits on testing are hampering the effort. The Ebola vaccine for chimps is made of a weakened rabies virus -- used in oral vaccines for animals -- with an added gene for the main surface glycoprotein from the Ebola virus. The vaccine was invented by Prof. Matthias Schnell's lab at Thomas Jefferson University in Philadelphia. The trial, consisting of oral and injected vaccines on 10 captive chimpanzees at a research centre at the University of Louisiana Lafayette, showed promising results for both. The chimpanzees developed immunity for Ebola, and suffered no side effects, said Dr. Peter Walsh, a biological anthropologist at the University of Cambridge who conducted the trials. However, the problem lies in recent changes in U.S. law stating that biomedical testing on chimpanzees is no longer legal.]
[The restrictions on medical testing on chimps in the wild need to be weighed on a case by case basis. A vaccine trial in this situation shows promise of benefiting them, as well as gorillas, as the chimps in this study would not be experimental subjects for humans, but rather they are being evaluated for a vaccine that shows strong potential to protect their species as soon as possible. - Mod.LK]
Funding
-----
28 Mar 2017 Sierra Leone: IMF considers possible finance for Sierra Leone as economy goes into reverse
[The economy of Sierra Leone is now going through its toughest phase, since the end of the Ebola [Ebola virus disease (EVD) epidemic. The government has run out of cash; donor funds have declined massively; inflation is rising out of control, unemployment remains chronically high; the taxation base has declined; public sector workers are going without pay; public services are facing huge financial constraints, and government contractors are not getting paid. The government has now realized that without private sector investments, it cannot diversify the economy and expand growth. Yet, public sector borrowing is rising fast, now standing at over USD 2 billion.]
[The Ebola outbreak in West Africa continues to have serious effects, not only on physical and psychological recovery of infected individuals but equally on the economy of the affected countries. - Mod.LK]
[Compiled by: Celeste Whitlow <whitlow.celeste@gmail.com>]
--
Communicated by:
ProMED-mail
<promed@promedmail.org>
[ProMED HealthMaps:
Liberia: http://healthmap.org/promed/p/54
Guinea: http://healthmap.org/promed/p/45
Sierra Leone: http://healthmap.org/promed/p/46]
*****************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org
In this update:
News
Documentary
Treatment
Convalescent plasma
Research
Chimpanzee vaccine
Funding
Sierra Leone
******
30 Mar 2017: Survivors remember Ebola epidemic as Samaritan's Purse releases documentary
http://www.deseretnews.com/article/865676776/Survivors-remember-Ebola-epidemic-as-Samaritan7s-Purse-releases-documentary.html
[Rev. Franklin Graham recounts the story in "Facing Darkness," a documentary produced by Samaritan's Purse recounting its fight to save the 1st American doctor diagnosed with Ebola [Ebola virus disease (EVD)] during the epidemic in West Africa. The film debuts in select theaters on Thursday [30 Mar 2017] and will return for encore showings on 10 Apr 2017.]
[This doctor, KB, was director of the Ebola treatment unit at ELWA (Eternal Love Winning Africa) Hospital when he was infected with the virus. - Mod.LK]
Treatment
----------
Citation. Burnouf T, Dhe JM, Abayomi A (30 Mar 2017). Convalescent Plasma and the Dose of Ebola Virus Antibodies. N Engl J Med 2017; 376:1296-1297 DOI: 10.1056/NEJMc1700090
[Letter to the editor:
After the clinical evaluation of convalescent plasma for Ebola virus (EBOV) disease in Guinea, van Griensven and colleagues [van Griensven J, Edwards T, de Lamballerie X, et al. Evaluation of convalescent plasma for Ebola virus disease in Guinea. N Engl J Med 2016;374:33-42] now provide additional data showing that the dose of neutralizing antibodies in the donations was low and that there was no apparent association between the dose of neutralizing antibodies and human survival. [van Griensven J, Edwards T, Baize S. Efficacy of convalescent plasma in relation to dose of Ebola virus antibodies. N Engl J Med 2016;375:2307-2309]. In our opinion, it is essential that the authors clarify precisely the stage of the procedure at which samples for neutralizing antibodies were taken. Was it at the time of plasma donation, after pathogen-inactivation treatment, or at the time of transfusion (after 40 days of storage, a delay that may possibly affect the efficacy of antibodies)? This information is critical because there is no publicly accessible documentation regarding the estimated effect that handling convalescent plasma processes have on the stability and activity of neutralizing EBOV antibodies. It is also important that the authors document how samples for antibody assessment were handled. This will help in defining standards required for handling convalescent plasma against emerging infectious agents in regions with limited available technology.
Reply by the author and colleagues: We thank Burnouf et al. for the pertinent questions. Donor samples sent to France for EBOV antibody testing were peripheral-blood samples collected on the day that donors came for automated plasma collection. These blood samples had not undergone pathogen reduction, because this process was applied only to the plasma bags collected for administration. The blood samples were stored at -30 deg C [-22 deg F] in Guinea, shipped on dry ice to the biosafety level 4 laboratory in France, and stored at 80 deg C [-112 deg F]. Samples had been thawed twice when antibody testing was done. Most of the plasma used in the trial was administered shortly after collection; the median time of plasma storage before administration was 8 days (interquartile range, 4 to 15). Plasma was stored for clinical use at 2 to 8 deg C [36 to 46 deg F] for up to 40 days and frozen at -30 deg C [-22 deg F] after that. We used a pathogen-reduction process, because when this study was conducted, there were many gaps in our knowledge of EBOV persistence and the presence of other transfusion-transmissible infections that could not be excluded under field conditions. Recently, Geisen et al. reported in a single donor that levels of IgG protein, EBOV IgG, and neutralizing antibodies were only slightly reduced after pathogen-reduction treatment with S59 amotosalen-ultraviolet A. We agree that more research is needed on the potential effect of pathogen reduction on the stability and activity of anti-EBOV neutralizing antibodies. (J van Griensven, P Gallian, X de Lamballerie for the Ebola-Tx Consortium)]
[See full report with references at DOI cited above. - Mod.LK]
[Information on the pathogen inactivator S59 amotosalen can be found here: https://www.ncbi.nlm.nih.gov/pubmed/12534321 - Mod.JH]
Research
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2 Apr 2017 The trick to saving chimps from Ebola
https://www.thestar.com/news/insight/2017/04/02/the-trick-to-saving-chimps-from-ebola.html
[A new study has shown great promise for an oral Ebola vaccine for chimpanzees and gorillas. But limits on testing are hampering the effort. The Ebola vaccine for chimps is made of a weakened rabies virus -- used in oral vaccines for animals -- with an added gene for the main surface glycoprotein from the Ebola virus. The vaccine was invented by Prof. Matthias Schnell's lab at Thomas Jefferson University in Philadelphia. The trial, consisting of oral and injected vaccines on 10 captive chimpanzees at a research centre at the University of Louisiana Lafayette, showed promising results for both. The chimpanzees developed immunity for Ebola, and suffered no side effects, said Dr. Peter Walsh, a biological anthropologist at the University of Cambridge who conducted the trials. However, the problem lies in recent changes in U.S. law stating that biomedical testing on chimpanzees is no longer legal.]
[The restrictions on medical testing on chimps in the wild need to be weighed on a case by case basis. A vaccine trial in this situation shows promise of benefiting them, as well as gorillas, as the chimps in this study would not be experimental subjects for humans, but rather they are being evaluated for a vaccine that shows strong potential to protect their species as soon as possible. - Mod.LK]
Funding
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28 Mar 2017 Sierra Leone: IMF considers possible finance for Sierra Leone as economy goes into reverse
[The economy of Sierra Leone is now going through its toughest phase, since the end of the Ebola [Ebola virus disease (EVD) epidemic. The government has run out of cash; donor funds have declined massively; inflation is rising out of control, unemployment remains chronically high; the taxation base has declined; public sector workers are going without pay; public services are facing huge financial constraints, and government contractors are not getting paid. The government has now realized that without private sector investments, it cannot diversify the economy and expand growth. Yet, public sector borrowing is rising fast, now standing at over USD 2 billion.]
[The Ebola outbreak in West Africa continues to have serious effects, not only on physical and psychological recovery of infected individuals but equally on the economy of the affected countries. - Mod.LK]
[Compiled by: Celeste Whitlow <whitlow.celeste@gmail.com>]
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Communicated by:
ProMED-mail
<promed@promedmail.org>
[ProMED HealthMaps:
Liberia: http://healthmap.org/promed/p/54
Guinea: http://healthmap.org/promed/p/45
Sierra Leone: http://healthmap.org/promed/p/46]
See Also
Ebola update (12): news, research, vaccine 20170326.4927435Ebola update (11): news, vaccine, research 20170312.4896304
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Ebola update (05): news, vaccine, funding, documentary films 20170129.4801064
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Ebola update (02): news, research, vaccine, comment 20170108.4750411
Ebola update (01): News, research, vaccine 20170103.4738060
2016
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Ebola update (32): Liberia, Guinea, support 20160410.4150454
Ebola update (31): Liberia, Guinea re-emergence, research, funding 20160406.4142990
Ebola update (30): Liberia re-emergence, Uganda NOT, RFI 20160404.4136987
Ebola update (29): Liberia re-emergence, Guinea contacts, news, RFI 20160402.4134878
Ebola update (28): news, research, vaccine 20160330.4128527
Ebola update (27): Ebola Reston virulence, Africa suspicious deaths RFI, news 20160327.4121931
Ebola update (26): Guinea flare-up, Liberia 20160324.4114807
Ebola update (25): Guinea flare-up, Liberia, Sierra Leone, research 20160320.4107350
Ebola update (24): Guinea, confirmed 20160317.4101955
Ebola update (23): comment, pregnant women, news, research 20160316.4098040
Ebola update (22): long-term sequelae, news, research 20160313.4090091
Ebola update (21): Sierra Leone, herd immunity, possible new drug 20160310.4081498
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