Patients With Comorbid Conditions Have Greater Risk of Hospital-Onset C. difficile Infection
A recent AHRQ-funded study found that adult hospital patients were at greater risk for acquiring Clostridium difficile infection if they were older, had received certain medications or had comorbid conditions including weight loss, certain blood disorders, renal failure or certain neurological disorders. Clostridium difficile, or C. diff, is a healthcare-associated intestinal infection that results in approximately 15,000 deaths per year. Using ICD-10 codes, researchers examined electronic health record data on patients admitted to the University of Maryland Medical Center between November 2015 and May 2017, and captured the presence of comorbid conditions using the AHRQ Elixhauser Comorbidity Index. They concluded that increased Elixhauser scores are associated with increased Clostridium difficileinfection risk, and that the use of methods such as the Elixhauser Comorbidity Index should be considered for risk-adjustment of Clostridium difficile infection rates. Access the abstract of the study, published in Infection Control and Hospital Epidemiology.
Infect Control Hosp Epidemiol. 2018 Mar;39(3):297-301. doi: 10.1017/ice.2018.10. Epub 2018 Feb 5.
Electronically Available Comorbid Conditions for Risk Prediction of Healthcare-Associated Clostridium difficile Infection.
Harris AD1, Sbarra AN2, Leekha S1, Jackson SS1, Johnson JK1, Pineles L1, Thom KA1.
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