Genet Med. 2017 Dec 14. doi: 10.1038/gim.2017.211. [Epub ahead of print]
From public health genomics to precision public health: a 20-year journey.
Khoury MJ1, Bowen MS1, Clyne M2, Dotson WD1, Gwinn ML3, Green RF1, Kolor K1, Rodriguez JL4, Wulf A1, Yu W1.
Abstract
In this paper, we review the evolution of the field of public health genomics in the United States in the past two decades. Public health genomics focuses on effective and responsible translation of genomic science into population health benefits. We discuss the relationship of the field to the core public health functions and essential services, review its evidentiary foundation, and provide examples of current US public health priorities and applications. We cite examples of publications to illustrate how Genetics in Medicine reflected the evolution of the field. We also reflect on how public-health genomics is contributing to the emergence of "precision public health" with near-term opportunities offered by the US Precision Medicine (AllofUs) Initiative.GENETICS in MEDICINE advance online publication, 14 December 2017; doi:10.1038/gim.2017.211.
- PMID:
- 29240076
- DOI:
- 10.1038/gim.2017.211
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