domingo, 7 de agosto de 2016

Clinical experience of unexpected findings in prenatal array testing. - PubMed - NCBI

Clinical experience of unexpected findings in prenatal array testing. - PubMed - NCBI

 2016 Aug;10(8):831-40. doi: 10.2217/bmm-2016-0054. Epub 2016 Jul 14.

Clinical experience of unexpected findings in prenatal array testing.

Abstract

AIM:

The aim of this study was to evaluate whether unexpected diagnoses (UD) made by prenatal array testing contribute to pregnancy management.

PATIENTS & METHODS:

In 2010-2015 in 19/4043 (0.5%) pregnancies an UD was made. The clinical usefulness of UDs was assessed based on the couple's responses during post-test counseling and their decisions.

RESULTS:

In 16/19 cases, the UD was helpful either for the couples in making a decision about the course of their pregnancy, for perinatal management or family genetic counseling.

CONCLUSION:

The majority of the pregnant couples found the UDs relevant for pregnancy management and genetic counseling. This adds another motive for offering whole genome array during pregnancy in patients who wish broad testing of their fetus.

KEYWORDS:

array; incidental findings; post-test counseling; prenatal diagnosis; pretest counseling; unexpected diagnosis

[PubMed - in process]


Public Health Genomics Knowledge Base (v1.2)

Genomics & Health Impact Update banner with DNA in background

August 4-11, 2016 

 genetic counseling

GENETIC COUNSELING


Last Updated: Aug 04, 2016

CDC Resources with and image of DNA

Seletced Insights & Reviews with various images of researchers in labortory environments

Epidemiology with an image of a crowd of people with a double helix

Translational Research with two images of people talking to a genetic counselor and an image of a hand with wrapped sequecing around it

Evidence Synthesis with an image of sequencing and a double helix

Practice & Implementation with images of people taking to a doctor and a nurse examining a child

Relevant Resources

No hay comentarios: