How to Build Bioinformatic Pipelines Using Galaxy
A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses
August 1, 2016|
© ISTOCK.COM/VASJAKOMANHuge swaths of modern biomedical science run on high-throughput DNA sequencers. These instruments can pump out data at an astonishing clip, producing gigabytes or more a day. But the end of the sequencing run is not even close to the end of the experiment. Researchers must somehow convert all those As, Cs, Gs, and Ts into knowledge by filtering, assembling, and interpreting the raw data to create a coherent biological picture.
That’s the role of bioinformaticians, and for labs lucky enough to have one on staff, data analysis is just an email request away. Many labs, though, aren’t so lucky. It’s not a lack of tools that is the problem: most popular bioinformatics software is free and open source. But downloading and installing those tools isn’t necessarily easy. Nor, for that matter, is using them. (See “Learning Bioinformatics,” The Scientist, July 2016.)