Genomics|Update|Current ► Severe Combined Immunodeficiency: Newborn Screening Saves Lives

Genomics|Update|Current

Severe Combined Immunodeficiency: Newborn Screening Saves Lives

What is SCID?  Severe combined immunodeficiency is a group of genetic disorders characterized by little or no immune response. SCID is sometimes known as "bubble boy" disease. Patients are susceptible to recurrent infections. New treatments can save many SCID patients. From the National Center Biotechnology Information, NIH

Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.
Antonia Kwan, et al. JAMA, August 20, 2014

Editorial: Newborn screening for severe combined immunodeficiency:  Progress and challenges.
Neil A. Holtzman. JAMA. 2014;312(7):701-702.  

Transplantation outcomes for severe combined immunodeficiency, 2000–2009
Sung-Yun Pai, et al. New England Journal Medicine, July 30, 2014

CDC information: Newborn screening: Saving Lives for 50 Years - CDC recently helped put into practice a newborn screening blood test for Severe Combined Immune Deficiency (SCID).

CDC funds Georgia, Oklahoma, and Virginia to screen for SCID (2013) 

The long quest for neonatal screening for SCID
R Buckley, J Allergy Immunology Infectious Diseases (2012)