About Advanced Molecular Detection Clips
Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in infectious disease public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged. Items marked I&E address aspects of implementation or evaluation in clinical or public health practice.
Advanced Molecular Detection Clips Content
NEWS
- Team Shows Proof of Concept for Mobile Phone-Enabled Mutation Analysis, Targeted Sequencing
Heger M. GenomeWeb, Jan 17, 2017. - Next Generation: Mobile Microscope Detects DNA Sequences
Olena A. The Scientist, Jan 17, 2017. - A Drug-Resistant Superbug May Be Stealthily Spreading
Kwon D. The Scientist, Jan 18, 2017. - Molecule shows ability to thwart pathogens' genetic resistance to antibiotic
phys.org, Jan 18, 2017. - Scientists Needn't Get A Patient's Consent To Study Blood Or DNA
Stein R. NPR, Jan 18, 2017. - Retroviruses Are Some 500 Million Years Old, Phylogenetic Analysis Shows
GenomeWeb, Jan 10, 2017.
EVENTS / TRAINING / WEB RESOURCES
- NLM Seeks Partners to Evaluate Malaria Screener’s Efficacy
NLM in Focus, Jan 13, 2017.
CONCEPTS / COMMENTS
- Delivering on Antimicrobial Resistance Agenda Not Possible without Improving Fungal Diagnostic Capabilities.
Denning David W et al. Emerging infectious diseases 2017 Feb (2) 177-183 - New Vaccines against Epidemic Infectious Diseases
Rottingen JA, et al. New Engl J Med, Jan 18, 2017.
METHODS / TOOLS
- Targeted DNA sequencing and in situ mutation analysis using mobile phone microscopy
Kuhnemund M, et al. Nat Comm 2016:13913 - Examining Sources of Error in PCR by Single-Molecule Sequencing.
Potapov Vladimir et al. PloS one 2017 (1) e0169774 - Evaluation of Oxford Nanopore MinION Sequencing for 16S rRNA Microbiome Characterization
Ma X, et al. bioRxiv, Jan 12, 2017. - FASTdoop: A Versatile and Efficient Library for the Input of FASTA and FASTQ Files for MapReduce Hadoop Bioinformatics Applications.
Ferraro Petrillo Umberto et al. Bioinformatics (Oxford, England) 2017 Jan - Top considerations for creating bioinformatics software documentation.
Karimzadeh Mehran et al. Briefings in bioinformatics 2017 Jan - Bayesian nonparametric clustering in phylogenetics: modeling antigenic evolution in influenza.
Cybis Gabriela B et al. Statistics in medicine 2017 Jan - Comparison of Collection Methods for Fecal Samples in Microbiome Studies.
Vogtmann Emily et al. American journal of epidemiology 2016 Dec - Evaluation of Methods for the Concentration and Extraction of Viruses from Sewage in the Context of Metagenomic Sequencing.
Hjelmsø Mathis Hjort et al. PloS one 2017 (1) e0170199
EVOLUTION / ECOLOGY / POPULATIONS
- Evolution of Variable Number Tandem Repeats and Its Relationship with Genomic Diversity in Salmonella Typhimurium.
Fu Songzhe et al. Frontiers in microbiology 2016 2002 - Sensitive next generation sequencing method reveals deep genetic diversity of HIV-1 in the Democratic Republic of the Congo.
Rodgers M A et al. Journal of virology 2017 Jan - Novel G9 rotavirus strains co-circulate in children and pigs, Taiwan.
Wu Fang-Tzy et al. Scientific reports 2017 Jan 40731 - Possible roles of new mutations shared by Asian and American Zika viruses.
Yokoyama Shozo et al. Molecular biology and evolution 2017 Jan - Comparative analysis of variation and selection in the HCV genome.
Patiño-Galindo Juan Ángel et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Jan - Microbial rRNA sequencing analysis of evaporative cooler indoor environments located in the Great Basin Desert region of the United States.
Lemons Angela R et al. Environmental science. Processes & impacts 2017 Jan
- MLST-Based Population Genetic Analysis in a Global Context Reveals Clonality amongst Cryptococcus neoformans var. grubii VNI Isolates from HIV Patients in Southeastern Brazil.
Ferreira-Paim Kennio et al. PLoS neglected tropical diseases 2017 Jan (1) e0005223 - Molecular Epidemiology of Ascaris Infection Among Pigs in Iowa.
Jesudoss Chelladurai Jeba et al. The Journal of infectious diseases 2017 Jan (1) 131-138
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.
Cerqueira Gustavo C et al. Proceedings of the National Academy of Sciences of the United States of America 2017 Jan - Transient In Vivo Resistance Mechanisms of Burkholderia pseudomallei to Ceftazidime and Molecular Markers for Monitoring Treatment Response.
Cummings Jason E et al. PLoS neglected tropical diseases 2017 Jan (1) e0005209 - Changing antimalarial drug resistance patterns identified by surveillance at three sites in Uganda.
Tumwebaze Patrick et al. The Journal of infectious diseases 2016 Dec - Genome-wide SNP analysis using 2b-RAD sequencing identifies the candidate genes putatively associated with resistance to ivermectin in Haemonchus contortus.
Luo Xiaoping et al. Parasites & vectors 2017 Jan (1) 31
DETECTION / DIAGNOSIS
- Whole-genome Sequencing for Surveillance of Invasive Pneumococcal Diseases in Ontario, Canada: Rapid Prediction of Genotype, Antibiotic Resistance and Characterization of Emerging Serotype 22F.
Deng Xianding et al. Frontiers in microbiology 2016 2099 - Microbial genomics and antimicrobial susceptibility testing.
Dunne W Michael et al. Expert review of molecular diagnostics 2017 Jan - Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing.
Eriksen Helle Brander et al. Emerging infectious diseases 2017 Feb (2) 320-323 - Emergence of Rare Species of Nontuberculous Mycobacteria as Potential Pathogens in Saudi Arabian Clinical Setting.
Varghese Bright et al. PLoS neglected tropical diseases 2017 Jan (1) e0005288 - A Pan-Lyssavirus Taqman Real-Time RT-PCR Assay for the Detection of Highly Variable Rabies virus and Other Lyssaviruses.
Wadhwa Ashutosh et al. PLoS neglected tropical diseases 2017 Jan (1) e0005258 - Miniaturized devices for point of care molecular detection of HIV.
Mauk Michael et al. Lab on a chip 2017 Jan - A novel quantitative PCR detects Babesia infection in patients not identified by currently available non-nucleic acid amplification tests.
Akoolo Lavoisier et al. BMC microbiology 2017 Jan (1) 16 - Molecular identification and genotyping of Trypanosoma cruzi DNA in autochthonous Chagas disease patients from Texas, USA.
Garcia Melissa N et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Jan
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- Genetic source tracking of an anthrax outbreak in Shaanxi province, China.
Liu Dong-Li et al. Infectious diseases of poverty 2017 Jan (1) 14 - Whole genome SNP typing to investigate methicillin-resistant Staphylococcus aureus carriage in a health-care provider as the source of multiple surgical site infections.
Roe Chandler C et al. Hereditas 2016 11 - Transmission of Extensively Drug-Resistant Tuberculosis in South Africa.
Shah N Sarita et al. The New England journal of medicine 2017 Jan (3) 243-253 - Population dynamics of HCV subtypes in injecting drug-users on methadone maintenance treatment in China associated with economic and health reform.
Zhou Sheng et al. Journal of viral hepatitis 2017 Jan - Molecular phylogeny of a novel human adenovirus type 8 strain causing a prolonged, multi-state keratoconjunctivitis epidemic in Germany.
Hage Elias et al. Scientific reports 2017 Jan 40680
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- The nucleotide changes within HBV core promoter/precore during the first 12weeks of nucleos(t)ide treatment might be associated with a better virological response.
Peng Yaqin et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Jan
HOST-MICROBE INTERACTIONS
- Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients.
Boutin Sébastien et al. Molecular and cellular pediatrics 2017 Dec (1) 1 - Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort.
Hill Cian J et al. Microbiome 2017 Jan (1) 4 - The Composition of Human Milk and Infant Faecal Microbiota Over the First Three Months of Life: A Pilot Study.
Murphy Kiera et al. Scientific reports 2017 Jan 40597 - Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer
Gagniere A, et al. Nat Rev Microbiol, Jan 3, 2017.
Note:
indicates that at least one CDC-affiliated author; 
indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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