Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force recommendation statement.

LeFevre ML; U.S. Preventive Services Task Force.

Abstract

DESCRIPTION:

Update of the 1996 U.S. Preventive Services Task Force (USPSTF) recommendation on aspirin prophylaxis in pregnancy.

METHODS:

The USPSTF reviewed the evidence on the effectiveness of low-dose aspirin in preventing preeclampsia in women at increased risk and in decreasing adverse maternal and perinatal health outcomes, and assessed the maternal and fetal harms of low-dose aspirin during pregnancy.

POPULATION:

This recommendation applies to asymptomatic pregnant women who are at increased risk for preeclampsia and who have no prior adverse effects with or contraindications to low-dose aspirin.

RECOMMENDATION:

The USPSTF recommends the use of low-dose aspirin (81 mg/d) as preventive medication after 12 weeks of gestation in women who are at high risk for preeclampsia. (B recommendation).

Comment in

Pre-eclampsia: low-dose aspirin for pre-eclampsia. [Nat Rev Nephrol. 2014]
Therapy: Low-dose aspirin to reduce the risk of pre-eclampsia? [Nat Rev Endocrinol. 2015]

PMID:: 25200125; [PubMed - in process]

----

full-text ►

National Guideline Clearinghouse | Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force recommendation statement.

U.S. Preventive Services Task Force

Guideline Title

Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force recommendation statement.

Bibliographic Source(s)

U.S. Preventive Services Task Force. Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014 Dec 2;161(11):819-26. [18 references]PubMed External Web Site Policy

Guideline Status

This is the current release of the guideline.

This guideline updates a previous version: U.S. Preventive Services Task Force. Guide to clinical preventive services. 2nd ed. Baltimore (MD): Williams & Wilkins; 1996. Chapter 70, Aspirin prophylaxis in pregnancy. p. 853-59. [31 references].

This guideline meets NGC's 2013 (revised) inclusion criteria.