Advanced Molecular Detection Clips
Spotlight
The Problem of Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae Detection. The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) is a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE detection. There is no single detection method that is ideal for all situations.
Advanced Molecular Detection Clips Content
NEWS
- Cepheid, USAID to Partner on Multidrug-Resistant TB National Action Plan
GenomeWeb, Jan 7, 2016. - New NIH awards will support development of therapeutic alternatives to traditional antibiotics
NIH, Jan 12, 2016. - Renaissance
Announcing a new journal, Nature Microbiology, Jan 8, 2016. - Tainted medical scopes have sickened hundreds in U.S., Europe, Senate investigation finds
Dennis B. Washington Post, Jan 13, 2016. - A Billion in Pandemic Prevention Is Worth a Trillion in Cure
Tozzi J. Bloomberg News, Jan 13, 2016. - Western diets damage gut microbiota over generations, in ways hard to reverse
Healy M. Los Angeles Times, Jan 14, 2016. - Hunt for Ebola’s wild hideout takes off as epidemic wanes
Callaway E. Nature, Jan 12, 2016. - C.D.C. May Warn Pregnant Women Against Travel to Countries With Zika Virus
McNeil DG. New York Times, Jan 13, 2016. - First Zika Virus Case in Continental United States Confirmed in Texas
Kelly JC. Medscape, Jan 11, 2016. - Iceman’s H. pylori Genome Hints at Ancient Migrations to Europe
Eck A. PBS.org, Jan 7, 2016. - Study: Melioidosis Underreported
Offord C. The Scientist, Jan 12, 2016.
EVENTS / TRAINING / WEB RESOURCES
- Nature Microbiology Community
(news and discussion) Launched Jan 8, 2016, by Nature Microbiology.
POLICY
- Defining antibiotic effectiveness and resistance: how a private party may soon rule judgments over susceptibility testing.
Doshi Peter et al. BMJ (Clinical research ed.) 2016 h6849 - FDA recommends nucleic acid testing to reduce HBV transmission
Healio, Jan 11, 2016. - Mapping Investments and Published Outputs in Norovirus Research: A Systematic Analysis of Research Funded in the United States and United Kingdom During 1997-2013.
Head Michael G et al. The Journal of infectious diseases 2016 Feb S3-7 - An assessment of US microbiome research
Stulberg E, et al. Nat Microbiol, Jan 11, 2016.
CONCEPTS / COMMENTS
- Phages Fight Back: Inactivation of the CRISPR-Cas Bacterial Immune System by Anti-CRISPR Proteins.
Maxwell Karen L et al. PLoS pathogens 2016 Jan (1) e1005282 - Come together
(editorial) Nature, Jan 6, 2016. - Forecasting Ecological Genomics: High-Tech Animal Instrumentation Meets High-Throughput Sequencing.
Shafer Aaron B A et al. PLoS biology 2016 Jan (1) e1002350 - Microbiome: Ecology of stable gut communities
McNally L, Brown SP. Nat Microbiol, Jan 14, 2016.
METHODS / TOOLS
- Integrated, Multi-cohort Analysis Identifies Conserved Transcriptional Signatures across Multiple Respiratory Viruses.
Andres-Terre Marta et al. Immunity 2015 Dec (6) 1199-211 - LAF: Logic Alignment Free and its application to bacterial genomes classification.
Weitschek Emanuel et al. BioData mining 2015 39
EVOLUTION / ECOLOGY / POPULATIONS
- Multilocus sequence typing of 102 Burkholderia pseudomallei strains isolated from China.
Fang Y et al. Epidemiology and infection 2016 Jan 1-7 - Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species.
Mosquera-Rendón Jeanneth et al. BMC genomics 2016 (1) 45 - Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus
Bos KI, et al. bioRxiv, Jan 12, 2016. - Identification and antimicrobial resistance prevalence of pathogenic Escherichia coli strains from treated wastewater effluents in Eastern Cape, South Africa.
Adefisoye Martins A et al. MicrobiologyOpen 2016 Jan - Uncovering the Potential Pan Proteomes Encoded by Genomic Strand RNAs of Influenza A Viruses.
Yang Chu-Wen et al. PloS one (1) e0146936 - Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection.
Raghwani Jayna et al. PLoS computational biology 2016 Jan (1) e1004694
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires
Burstein D, et al. Nat Genet, Jan 11, 2016. - Emergent and evolving antimicrobial resistance cassettes in community-associated fusidic acid and meticillin-resistant Staphylococcus aureus.
Ellington Matthew J et al. International journal of antimicrobial agents 2015 May (5) 477-84 - Whole genome sequencing of diverse Shiga toxin-producing and non-producing Escherichia coli strains reveals a variety of virulence and novel antibiotic resistance plasmids.
Losada Liliana et al. Plasmid 2015 Dec - Persistent Infections by Non-Typhoidal Salmonella in Humans: Epidemiology and Genetics.
Marzel Alex et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Jan - Global comparison of drug resistance mutations following first line antiretroviral therapy across HIV-1 subtypes
Huang A, et al. Open Forum Infect Dis, Nov 3, 2015. - Cryptococcus: from environmental saprophyte to global pathogen.
May Robin C et al. Nature reviews. Microbiology 2015 Dec
DETECTION / DIAGNOSIS
- Recent development of mass spectrometry and proteomics applications in identification and typing of bacteria.
Cheng Keding et al. Proteomics. Clinical applications 2016 Jan - Integrating Rapid Diagnostics and Antimicrobial Stewardship in Two Community Hospitals Improved Process Measures and Antibiotic Adjustment Time.
Lockwood Ashley M et al. Infection control and hospital epidemiology 2016 Jan 1-8 - The Problem of Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae Detection.
Lutgring Joseph D et al. Journal of clinical microbiology 2016 Jan (CDC Author) - Optimized MOL-PCR for Characterization of Microbial Pathogens.
Wuyts Véronique et al. Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2016 13.15.1-13.15.15 - Impact of rapid identification of Acinetobacter Baumannii via matrix-assisted laser desorption ionization time-of-flight mass spectrometry combined with antimicrobial stewardship in patients with pneumonia and/or bacteremia.
Wenzler Eric et al. Diagnostic microbiology and infectious disease 2016 Jan (1) 63-8 - Performance and Verification of a Real-time PCR Assay Targeting gyrA Gene for Prediction of Ciprofloxacin Resistance in Neisseria gonorrhoeae.
Hemarajata P et al. Journal of clinical microbiology 2016 Jan - Whole-genome sequencing for the diagnosis of drug-resistant tuberculosis.
Javid Babak et al. The Lancet. Infectious diseases 2016 Jan (1) 17 - Quantifying Next Generation Sequencing Sample Pre-Processing Bias in HIV-1 Complete Genome Sequencing.
Vrancken Bram et al. Viruses 2016 (1) - A Cost-Effectiveness Analysis of Multiplex PCR with Magnetic Resonance Detection versus Empiric or Blood Culture Directed Therapy for the Management of Suspected Candidemia.
Walker Brandon et al. Journal of clinical microbiology 2016 Jan
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- Whole-genome sequencing reveals transmission of vancomycin-resistant Enterococcus faecium in a healthcare network.
Brodrick Hayley J et al. Genome medicine 2016 (1) 4 - Diagnosis of Tuberculosis in Three Zoo Elephants and a Human Contact - Oregon, 2013.
Zlot Amy et al. MMWR. Morbidity and mortality weekly report 2016 (52) 1398-402 - High Proportion of Asymptomatic Infections in an Outbreak of Hepatitis E Associated With a Spit-Roasted Piglet, France, 2013.
Guillois Yvonnick et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Feb (3) 351-7
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa.
Guo Qiaoyun et al. Scientific reports 2016 19141 - Characterization of invasive Neisseria meningitidis from Atlantic Canada, 2009 to 2013: With special reference to the nonpolysaccharide vaccine targets (PorA, factor H binding protein, Neisseria heparin-binding antigen and Neisseria adhesin A).
Tsang Raymond Sw et al. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie me´dicale / AMMI Canada (6) 299-304 - Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial.
Lee Christine H et al. JAMA 2016 Jan (2) 142-149 - Prevalence of K65R in patients treated with tenofovir disoproxil fumarate: recommendations based on the Frankfurt HIV Cohort Study Resistance Database (FHCS-RD).
Reinheimer Claudia et al. Medical microbiology and immunology 2016 Jan - Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures.
Nakaya Helder I et al. Immunity 2015 Dec (6) 1186-98 - Dynamics of hepatitis B virus quasispecies heterogeneity in association with nucleos(t)ide analogue treatment determined by MALDI-TOF MS.
Rybicka M et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2015 Mar (3) 288.e1-4
HOST-MICROBE INTERACTIONS
- Revised estimates for the number of human and bacteria cells in the body
Sender R, et al. bioRxiv, Jan 6, 2016. - Systemic sclerosis is associated with a unique colonic microbial consortium.
Volkmann Elizabeth R et al. Arthritis & rheumatology (Hoboken, N.J.) 2016 Jan - Human milk microbiota profiles in relation to birthing method, gestation and infant gender.
Urbaniak Camilla et al. Microbiome 2016 (1) 1 - SFRP1 variations influence susceptibility and immune response to Mycobacterium tuberculosis in a Chinese Han population.
Zhao Zhenzhen et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jan 259-65 - IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals.
Machmach K et al. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2015 Mar (3) 289.e1-4 - Biological implications and therapeutic significance of DNA methylation regulated genes in cervical cancer.
Bhat Samatha et al. Biochimie 2015 Dec - Environmental correlation analysis for genes associated with protection against malaria.
Mackinnon Margaret J et al. Molecular biology and evolution 2016 Jan - Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria.
Shah Shivang S et al. Malaria journal 2016 (1) 13
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