Final Recommendation Statement: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication - US Preventive Services Task Force

Final Recommendation Statement: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication - US Preventive Services Task Force

Final Recommendation Statement:

Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults

Final Recommendation Statement: Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults The U.S. Preventive Services Task Force released today a final recommendation statement on vitamin D, calcium, or combined supplementation for the primary prevention of fractures in community-dwelling adults. The Task Force found insufficient evidence to recommend for or against vitamin D and calcium supplementation to prevent fractures in most adults at higher doses and recommends against them at lower doses. To view the recommendation and the evidence on which it is based, please go here. The final recommendation statement can also be found in the April 17 online issue of JAMA. The Final Recommendation Statement Is Available

FINAL RECOMMENDATION SUMMARY See the full statement

Population Recommendation Grade Men and premenopausal women The USPSTF concludes that the current evidence is insufficient to assess the balance of the benefits and harms of vitamin D and calcium supplementation, alone or combined, for the primary prevention of fractures in men and premenopausal women. I Postmenopausal women The USPSTF concludes that the current evidence is insufficient to assess the balance of the benefits and harms of daily supplementation with doses greater than 400 IU of vitamin D and greater than 1000 mg of calcium for the primary prevention of fractures in community-dwelling, postmenopausal women. I Postmenopausal women The USPSTF recommends against daily supplementation with 400 IU or less of vitamin D and 1000 mg or less of calcium for the primary prevention of fractures in community-dwelling, postmenopausal women. D

WHY THIS MATTERS

“We found that taking low doses of vitamin D and calcium does not prevent women who have gone through menopause from getting fractures. We need more research to understand if taking higher doses of vitamin D or calcium helps to prevent fractures in women who have gone through menopause—or at any dose for men or younger women.” – Task Force member Carol Mangione, M.D., M.S.P.H.

WHERE WE ARE IN THE PROCESS

Draft Research Plan Final Research Plan Draft Recommendation / Draft Evidence Review  Final Recommendation / Evidence Summary