NCTR Centers of Excellence > Bioinformatics

Bioinformatics

The Center for Bioinformatics conducts research in bioinformatics and chemoinformatics, and develops and coordinates informatics capabilities within NCTR, across FDA Centers, and in the larger toxicology community. The goal of the toxicoinformatics group is to develop methods for the analysis and integration of omics (genomic, transcriptomic, proteomic, and metabolomic) databases with the objective of knowledge discovery and the elucidation of mechanisms of toxicity.

Some of NCTR's toxicoinformatics projects and tools include:


>> ArrayTrack
ArrayTrack™
DNA microarray data management, mining, analysis, and interpretation software

>> Decision Forest
Decision Forest
A novel pattern recognition method for analysis of data from microarray experiments, proteomics research, and predictive toxicology

>> Endocrine Disruptor Knowledge Base (EDKB)
Endocrine Disruptor Knowledge Base
Scientific resources to predict estrogen and androgen activity

>> MicroArray Quality Control (MAQC) Project
MicroArray Quality Control (MAQC)
Development of microarray quality control metrics and thresholds

>> Mold2
Mold2
Generate molecular descriptors from two-dimensional structures


Contact Information

For more information, please contact Dr. Weida Tong at 870-543-7142 or weida.tong@fda.hhs.gov.

NCTR Centers of Excellence > Bioinformatics