Genomics|Update|Current ► Primary Immunodeficiency Disorders: Genetics & Public Health

Genomics|Update|Current

Primary Immunodeficiency Disorders: Genetics & Public Health

CDC paper Prevalence and morbidity of primary immunodeficiency diseases, United States 2001–2007. 
Kobrynski L, Waltenburg Powell R, Bowen S J Clin Immunol. 2014 Sep 26.  

CDC information: Newborn Screening: Severe Combined Immunodeficiency (SCID)

CDC Flickr album: Newborn Screening: Family Stories includes stories from families with children affected by SCID

CDC Flickr album: Newborn Screening: Public Health Stories CDC scientist Robert Vogt talks about his work on newborn screening for SCID

Primary immunodeficiency disorders, mostly inherited, weaken the immune system, allowing repeated infections and other health problems to occur more easily, from the Mayo Clinic

Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery
Vicki Modell, et al. Immunologic Research March 2014

The 10 warning signs of primary immunodeficiency disorders 

Applying public health strategies to primary immunodeficiency diseases: A potential approach to genetic disorders 
MMWR (2004)

The use of databases in primary immunodeficiencies.
Kindle G, et al. Curr Opin Allergy Clin Immunol. 2014 Sep 15.

Contribution of high-throughput DNA sequencing to the study of primary immunodeficiencies.
Picard C, et al. Eur J Immunol. 2014 Oct;44(10):2854-61.

Utility of next generation sequencing in clinical primary immunodeficiencies.
Raje N, et al. Curr Allergy Asthma Rep. 2014 Oct;14(10):468.

Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.
Kwan A, et al. JAMA. 2014 Aug 20;312(7):729-38.

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies 
Casanova JL, et al. J Exp Med 2014 Oct

Increased safety of gene therapy for X-linked SCID, by Rebecca Burbidge, PHG Foundation, Oct 13